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S100A4
| Symbol: | S100A4 | | Name(s): | S100 calcium binding protein A4 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17497677 |
Pathways of signaling by S100A4, by its interaction with and sequestration of p53, and by Notch also seem differentially operational in the induction of apoptosis |
| 18154362 |
Localized activation of S100A4 at the cell periphery was observed in fibroblasts during random migration and following stimulation with lysophosphatidic acid, a known activator of cell motility and proliferation. |
| 17673926 |
Hypomethylation is an important mechanism of regulating the expression of the S100A4 gene in endometrial carcinomas. |
| 17565747 |
Results show that S100A4 is expressed preferentially by various cell types present in the tumor microenvironment (macrophages, fibroblasts, activated lymphocytes), rather than by the tumor cells themselves. |
| 17550972 |
Results suggest that CTGF plays a crucial role in migratory/invasive processes in human breast cancer by a mechanism involving activation of the integrin-alphavbeta3-ERK1/2-S100A4 pathway. |
| 16243835 |
S100A4 is a mediator of metastasis [review] |
| 14640694 |
MTS1 regulates nonmuscle myosin IIA assembly by monomer sequestration and is able to regulate cell shape and motility through the modulation of myosin-IIA function. |
| 17504119 |
Review of implications of S11A4 involvement with and binding to its targets sheds additional light on the role of S100A4 in the control of tumor cell motility and migration. |
| 12645008 |
S100A4 showed the weakest expression of 3 S100 proteins (including S100A5 and S100A13) in the cells and fibers of the hippocampus and the temporal cortex at all stages examined (from 12 to 33 weeks of gestation). |
| 16265347 |
overexpression of S100A4 is associated with thyroid tumour invasion and metastasis and it may be a potential target for therapeutic intervention | →View more information from publications. |
Recent Publications on S100A4: |  |
Grafted neural progenitors migrate and form neurons after experimental traumatic brain injury.
PURPOSE: Neural stem and progenitor cells (NSPC) generate neurons and... | 30th October, 2009
| Department of Medical Biochemistry and Microbiology, Uppsala University,
| Restor Neurol Neurosci. 2009;27(4):323-34.
DOI Direct Link |
Epidermal growth factor receptor ligands as new extracellular targets for the metastasis-promoting S100A4 protein.
The function of S100A4, a member of the calcium-binding S100 protein... | 21st October, 2009
| Department of Molecular Cancer Biology, Institute of Cancer Biology,
| FEBS J. 2009 Oct;276(20):5936-48. Epub 2009 Sep 9.
DOI Direct Link |
Human tissue-engineered bone produced in clinically relevant amounts using a semi-automated perfusion bioreactor system: a preliminary study.
The aim of this study was to evaluate a semi-automated perfusion... | 17th October, 2009
| Institute for Biomedical Technology, University of Twente, 3720 AB
| J Tissue Eng Regen Med. 2009 Oct 15.
DOI Direct Link |
The metastasis-associated anterior gradient 2 protein is correlated with poor survival of breast cancer patients.
The secreted metastasis-inducing protein, human anterior gradient 2... | 17th October, 2009
| Cancer Tissue Bank Research Centre, University of Liverpool, UK.
| Am J Pathol. 2009 Nov;175(5):1848-57. Epub 2009 Oct 15.
DOI Direct Link |
Metastasis-inducing S100A4 protein is associated with the disease activity of rheumatoid arthritis.
Objectives. To evaluate the association between metastasis-inducing... | 16th October, 2009
| Department of Rheumatology of the First Faculty of Medicine, Institute of
| Rheumatology (Oxford). 2009 Oct 14.
DOI Direct Link |
→View more research publications. |
S100A4 results (if any) from reagent suppliers | 
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S100A4 antibody, prediluted (ab27427) | Abcam
Rabbit polyclonal to S100A4, prediluted. S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an ...
http://www.abcam.com/S100A4-antibody-prediluted-ab27427.html...
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S100A4 monoclonal antibody (M01)
Abgent develops powerful tools to profile posttranslational modifications related to cellular function and disease. Abgent antibodies target protein
kinases ...
http://www.abgent.com/products/catalog_no/AT3757a_S100A4_mon...
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S100A4 antibodies: Cardiovascular > Heart > Cardiogenesis ...
S100A4 antibodies. ... S100A4 antibody [NJ4F3]. Flow Cyt, cELISA, ELISA. Images. Mouse monoclonal. Reacts with: Hu. ab75550 · S100A4 antibody, prediluted ...
http://www.abcam.com/index.html?t=130236&pt=1&c=4447&ei=&mu=...
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monoclonal antibody template
S100A4 is 101 amino acids (aa) in length and contains two ... S100A4 is involved in regulating the metastatic behavior of tumor cells. It is ubiquitously ...
http://www.rndsystems.com/pdf/MAB4138.pdf...
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S100A4 peptide (ab41530) | Abcam
S100A4 peptide. S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain ...
http://www.abcam.com/S100A4-peptide-ab41530.html...
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S100A4
DATA SHEET. Rev 120904B. S100A4. Rabbit Polyclonal Antibody. Cat. #RB-9411-P0, - P1, or -P (0.1ml, 0.5ml, or 1.0ml at 200痢/ml) (Purified Ab with BSA and ...
http://www.labvision.com/pdf/9411.pdf...
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Anti-S100A4
Antibodies , Primary Antibodies , Neuroscience , Anti-S100A4; Host: rabbit polyclonal; Species Reactivity: human; Application: IHC-P.
http://www.anaspec.com/products/product.asp?id=46914...
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