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S100A9
| Symbol: | S100A9 | | Name(s): | S100 calcium binding protein A9 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | 60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF, P14 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18060880 |
These data indicate that S100A8/A9-induced cell death involves Bak, selective release of Smac/DIABLO and Omi/HtrA2 from mitochondria, and modulation of the balance between pro- and anti-apoptotic proteins. |
| 17636430 |
Report showed S100A9 was expressed human bone and cartilage cells and may contribute to calcification of the cartilage matrix and its replacement with trabecular bone, and to regulation of redox in bone resorption. |
| 17787039 |
Data suggest that S100 proteins calprotectin and S100A12 are related to radiographic changes rather than disease activity in psoriatic arthritis with low disease activity. |
| 17936757 |
The homo-oligomeric forms of S100A8 and S100A9 are readily degraded by proteases, and the preferred hetero-oligomeric S100A8/A9 complex displays a high resistance even against proteinase K degradation. |
| 17852869 |
Serum calprotectin (S100A8/S100A9)and S100A12 are increased in children with inflammatory bowel disease and indicate disease activity. |
| 17895549 |
MRP8/14 may be involved in the pathogenesis of sarcoid granulomas. The measurement of serum MRP8/14 levels is useful for the diagnosis of sarcoidosis. |
| 13130482 |
Since MRP-8/MRP-14 exhibit direct effects on leukocyte adhesion to the vascular endothelium, their extensive expression in the epidermis indicates an active role for these S-100 proteins in the initial phase of this systemic autoimmune disease. |
| 17126494 |
Authors hypothesize that L1AG might become internalized nonspecifically into target cells, perhaps by pinocytosis. This predicts cell survival of cultured stomach tumor cells as a function of L1AG concentration. |
| 12645005 |
plays a prominent role in leukocyte trafficking and arachidonic acid metabolism; elevated levels of S100A9 and S100A8 in body fluids of inflamed tissues strengthen the view that these molecules are important players in fighting inflammation [review] |
| 12137245 |
These data indicate that calprotectin (MRP8 and MRP14) has higher specific activity to induce apoptosis than the individual subunits, and that the mechanism is exclusion of zinc from target cells. | →View more information from publications. |
Recent Publications on S100A9: |  |
S100A8 and S100A9 expression is a crucial factor for dedifferentiation in thyroid carcinoma.
BACKGROUND: S100A8 plays a role in various functions of myeloid cells by... | 23rd October, 2009
| Department of Surgery, Kuma Hospital, 8-2-35, Shimoyamate-dori, Chuo-ku,
| Anticancer Res. 2009 Oct;29(10):4157-61.
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S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis.
The nuclear factor-kappaB (NF-kappaB) signaling pathway has been recently... | 21st October, 2009
| Division of Signal Transduction and Growth Control (A100), German Cancer
| Hepatology. 2009 Oct;50(4):1251-62.
DOI Direct Link |
Mrp-8 and -14 mediate CNS injury in focal cerebral ischemia.
Several reports have recently demonstrated a detrimental role of Toll-like... | 20th October, 2009
| Max-Planck-Institute for Molecular Genetics, Ihnestr.73, 14195 Berlin,
| Biochim Biophys Acta. 2009 Oct 14.
DOI Direct Link |
Calprotectin--a novel marker of obesity.
BACKGROUND: The two inflammatory molecules, S100A8 and S100A9, form a... | 14th October, 2009
| The Centre of Inflammation and Metabolism, Department of Infectious
| PLoS One. 2009 Oct 12;4(10):e7419.
DOI Direct Link |
Complicated urinary tract infection is associated with uroepithelial expression of proinflammatory protein S100A8.
F344 rats chronically infected with Ureaplasma parvum develop two distinct... | 14th October, 2009
| University of Florida, College of Veterinary Medicine, Department of
| Infect Immun. 2009 Oct;77(10):4265-74. Epub 2009 Aug 10.
DOI Direct Link |
→View more research publications. |
S100A9 results (if any) from reagent suppliers | 
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S100A9 antibody (ab75478) | Abcam
Rabbit polyclonal to S100A9. S100A9 is a member of the S100 family of proteins. S100A9, together with S100A8 forms a heterodimeric protein complex, ...
http://www.abcam.com/S100A9-antibody-ab75478.html...
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S100A9 monoclonal antibody (M01)
Immunofluorescence of monoclonal antibody to S100A9 (AT3764a) on MCF-7 cell . ... Western Blot analysis of S100A9 expression in transfected 293T cell line ...
http://www.abgent.com/products/catalog_no/AT3764a_S100A9_mon...
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S100A9 antibodies: Immunology > Innate Immunity > Macrophage ...
S100A9 antibodies. ... S100A9 antibody [NO.134]. ELISA, sELISA. Mouse monoclonal ... S100A9 antibody [S32.2]. Flow Cyt, IHC-FoFr, ELISA, IHC-P ...
http://www.abcam.com/index.html?t=270942&pt=1&c=480&ei=&mu=r...
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Monoclonal Antibody To Human MRP14 (S100A9)
protein complex, also called S100A9 or Calgranulin B. It is useful for the characterization of circulating granulocytes or inflammatory infiltrates of the
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http://www.bma.ch/n2n/upload/product/t-1028.pdf...
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S100A9/MRP-14, Clone 1H9, Human mAb
the S100A9 (MRP-14) protein. The calcium-binding, migration inhibitory ... In inflammatory conditions small venueles stain with both anti-S100A8 and S100A9.
...
http://www.cellsciences.com/PDF/HM2176.pdf...
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ORDERING INFORMATION
Mouse S100A9 specific IgG was purified by mouse S100A9 affinity chromatography. S100A9, also known as calgranulin B, migration inhibitory ...
http://www.rndsystems.com/pdf/af2065.pdf...
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MONOCLONAL ANTIBODY TO HUMAN S100A8/A9 (MRP-8/MRP-14), CALPROTECTIN
Hessian, P et al; The heterodimeric complex of MRP-8 (S100A8) and MRP-14 (S100A9 ) – Antibody recognition, epitope definition and the implications for ...
http://www.hbt.nl/HM2156.pdf...
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