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S100A11


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Symbol:S100A11
Name(s):S100 calcium binding protein A11
Type:protein-coding
Organism:Homo sapiens
Synonyms:MLN70, S100C
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17932043 Ca(2+)-dependent binding of S100A11 to ANXA1 facilitated the binding of the latter to cPLA(2), resulting in inhibition of cPLA(2) activity
17476473 S100C/A11-mediated pathway is at least partly involved in conferring upon human squamous cell cancers resistant to TGFbeta-induced growth suppression
17537172 The results indicated that the upregulation of S100A11 expression in non-small cell lung cancer tissues was significantly associated with higher tumor-node-metastasis stage (P = 0.001) and positive lymph node status
17624315 Proteomic mapping using a selective subcellular extraction kit revealed S100A11 as a new member of the S100 protein family modulated by glucocorticoids in keratinocytes.
15241500 Of several tested, only an N-terminal peptide with 19 amino acid residues induces apoptosis in human keratinocyte and squamous-cell carcinoma cell lines
14962086 that redistribution along microtubules is a mechanism whereby S100A11 is positioned at the cell periphery in preparation for transglutaminase-dependent crosslinking.
17000675 Expression of S100A11, a putative tumor suppressor gene, is increased in the early stage of pancreatic carcinogenesis and decreased during subsequent progression to cancer.
15138568 Up-regulation of S100A11 was associated with the development of lymph node metastases in gastric cancer
11873942 S100C is a new tumor marker protein, the expression of which significantly decreases after malignant transformation of human tissues.
15322223 findings suggest that S100A11 has an anti-apoptotic function and is related to the process of growth of human uterine leiomyoma

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDannexin IS100 calcium binding protein A11--Pubmed
HPRDannexin IS100 calcium binding protein A11--Pubmed
HPRDnucleolinS100 calcium binding protein A11--Pubmed
HPRDnucleolinS100 calcium binding protein A11--Pubmed
HPRDS100 calcium binding protein A11S100 calcium binding protein A11--Pubmed
BINDS100 calcium binding protein A11S100 calcium binding protein A11S100A11 interacts with itself.-Pubmed
HPRDS100 calcium binding protein A11S100 calcium-binding protein, beta--Pubmed
BINDS100 calcium binding protein A11S100 calcium-binding protein, betaS100A11 interacts with S100B.-Pubmed

Recent Publications on S100A11:

Pubmed Logo
Proteomics-based identification of two novel direct targets of hypoxia-inducible factor-1 and their potential roles in migration/invasion of cancer cells.
Hypoxia-inducible factor-1 (HIF-1), consisting of oxygen-sensitive...
29th October, 2009
Institute of Health Sciences, Chinese Academy of Sciences/Shanghai Proteomics. 2009 Aug;9(15):3901-12.
DOI Direct Link
Annexin I and annexin II N-terminal peptides binding to S100 protein family members: specificity and thermodynamic characterization.
The S100 proteins make up a family of dimeric calcium binding proteins...
23rd October, 2009
Department of Biology, Rensselaer Polytechnic Institute, Troy, New York Biochemistry. 2009 Mar 31;48(12):2788-98.
DOI Direct Link
Expression patterns of S100 proteins in melanocytes and melanocytic lesions.
S100 proteins are differentially expressed in tumours of epithelial...
16th October, 2009
Departments of Clinical Genetics, Sahlgrenska University Hospital, Melanoma Res. 2009 Aug;19(4):215-25.
DOI Direct Link
Proteomic analysis of the triglyceride-rich lipoprotein-laden foam cells.
In hypertriglyceridaemic individuals, atherosclerogenesis is associated...
17th September, 2009
Department of Biochemistry and Molecular Biology, Tongji Medical College, Mol Cells. 2009 Sep 7.
DOI Direct Link
Inhibition of S100A11 gene expression impairs keratinocyte response against vaccinia virus through downregulation of the IL-10 receptor 2 chain.
BACKGROUND: The mechanism that predisposes patients with atopic dermatitis...
9th September, 2009
Department of Pediatrics, National Jewish Health, Denver, Colo 80206, USA. J Allergy Clin Immunol. 2009 Aug;124(2):270-7, 277.e1. Epub 2009 Jul 3.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7611839 Methods for diagnosing RCC and other solid tumors
6998232 Methods of diagnosing bladder cancer
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
7112668 Polypeptides and nucleic acids encoded thereby
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

View more patents.

S100A11 results (if any) from reagent suppliers

Google CSE Logo
Phospho-S100A11-pY32 Antibody
Dot blot analysis of anti-Phospho-S100A11-pY32 Antibody (Cat.#AP3601a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot
...
http://www.abgent.com/products/catalog_no/AP3601a_Phospho_S1...

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monoclonal antibody template
29 Jul 2008 ... treatment or calcium-induced S100A11 serine phosphorylation induces nuclear ... of S100A11 and subsequent growth inhibition in normal cells. ...
http://www.rndsystems.com/pdf/MAB5167.pdf...

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S100A11 protein (His tag) (ab55569) | Abcam
S100A11 protein (His tag). S100A11 (EMAP (endothelial monocyte-activating polypeptide), Calgizzarin) is a calcium-binding polypeptide with cytokine ...
http://www.abcam.com/S100A11-protein-His-tag-ab55569.html...

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S100A11 - R&D Systems
S100A11, also called calgizzarin or S100C, is an antiproliferative 10 kDa protein that is a member of the S100 family of EF-hand calcium binding proteins.
...
http://www.rndsystems.com/molecule_detail.aspx?m=3935...

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S100B antibody, S-100 (beta-beta) Antibody, Mouse Monoclonal Antibody
S-100 (beta-beta) interacts with S100A11, IgG (GenWay Catalog #: 20-511-240186). S-100 (beta-beta) interacts with S100A11, IgG (GenWay Catalog ...
http://www.genwaybio.com/product_info.php?products_id=240186...

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Abgent - Phosphospecific Antibody
AP3630aNEW, Phospho-S100A11-pS6 Antibody, DB, E, H. AP3601aNEW, Phospho-S100A11- pY32 Antibody, DB, E, H. AP3247a, Phospho-SEPARIN-S1126 Antibody, IHC, DB, E ...
http://www.abgent.com/products/category/phosphospecific...

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S100 antibody, S100 [4C4.9] Antibody, Mouse Monoclonal Antibody
S100A11 Human, Protein · S100P Human, Protein. PRODUCT INTERACTIONS: S100 [4C4.9 ] interacts with S100b Human, Protein (GenWay Catalog #: 20-272-192567). ...
http://www.genwaybio.com/product_info.php?products_id=192567...

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