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S100A13


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Gene DB Home
Symbol:S100A13
Name(s):S100 calcium binding protein A13
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12645008 detected in both cells and fibers of the hippocampus at 12 weeks gestation, slightly stronger at 20 weeks, and then decreased with age. In the temporal cortex, strong in all cellular layers at 12 to 24 weeks, declined with age from 28 weeks onwards.
12746488 Stress-induced export of IL-1alpha involves the intracellular association with the Cu2+-binding protein, S100A13; the expression of a S100A13 mutant functions as a dominant-negative repressor of IL-1alpha release.
15821778 data show that the expression of endoglin and S100A13 protein corresponds to the activation of the endothelial cells in the process of endometriotic angiogenesis
17077500 Human S100A13 was heterologously expressed in Escherichia coli, purified and crystallized by the hanging-drop vapour-diffusion method.
16773219 In human astrocytic gliomas, S100A13 was significantly up-regulated in high-grade vascularized gliomas. Moreover, S100A13 expression significantly correlated with microvessel density and tumour grading.
15033494 S100A13 protein translocation in response to extracellular S100 is mediated by receptor for advanced glycation endproducts in human endothelial cells
17374362 S100A13 is a homodimer with four EF-hand motifs in an asymmetric unit, displaying a folding pattern similar to other S100 members. S100A13 has the unique structural feature with all alpha-helices being amphiphilic.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDfibroblast growth factor 1 isoform 1 precursorS100 calcium binding protein A13--Pubmed
HPRDfibroblast growth factor 1 isoform 1 precursorS100 calcium binding protein A13--Pubmed
HPRDinterleukin 1, alphaS100 calcium binding protein A13--Pubmed
HPRDinterleukin 1, alphaS100 calcium binding protein A13--Pubmed
HPRDS100 calcium binding protein A13synaptotagmin I--Pubmed
HPRDS100 calcium binding protein A13synaptotagmin I--Pubmed

Recent Publications on S100A13:

Pubmed Logo
A residue-level investigation of the equilibrium unfolding of the C2A domain of synaptotagmin 1.
Fibroblast growth factor (FGF) 1 is known to be released in response to...
31st October, 2009
Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan, Arch Biochem Biophys. 2009 Oct 15;490(2):158-62. Epub 2009 Aug 31.
DOI Direct Link
NMR characterization of copper and lipid interactions of the C2B domain of synaptotagmin I-relevance to the non-classical secretion of the human acidic fibroblast growth factor (hFGF-1).
Human fibroblast growth factor (hFGF-1) is a approximately 17 kDa heparin...
20th October, 2009
Department of Chemistry and Biochemistry, University of Arkansas, Biochim Biophys Acta. 2009 Oct 14.
DOI Direct Link
Calcium-binding protein S100P is highly expressed during the implantation window in human endometrium.
OBJECTIVE: To investigate S100P expression and localization in human...
3rd October, 2009
Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Fertil Steril. 2009 Sep 29.
DOI Direct Link
S100A13-C2A binary complex structure-a key component in the acidic fibroblast growth factor for the non-classical pathway.
Fibroblast growth factors (FGFs) are key regulators of cell proliferation,...
21st April, 2009
Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Biochem Biophys Res Commun. 2009 Mar 13;380(3):514-9. Epub 2009 Jan 29.
DOI Direct Link
Protein folding does not prevent the nonclassical export of FGF1 and S100A13.
Newly synthesized proteins are usually exported through the endoplasmic...
17th April, 2009
Maine Medical Center Research Institute, Scarborough, 81 Research Dr., Biochem Biophys Res Commun. 2009 Apr 10;381(3):350-4. Epub 2009 Feb 20.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
6103497 Human S100 proteins
6117989 Human calcium-binding proteins
6706867 DNA array sequence selection
6998232 Methods of diagnosing bladder cancer

View more patents.

S100A13 results (if any) from reagent suppliers

Google CSE Logo
S100A13 monoclonal antibody (M01)
Immunofluorescence of monoclonal antibody to S100A13 (AT3753a) on HeLa cell . ... Western Blot analysis of S100A13 expression in transfected 293T cell line
...
http://www.abgent.com/products/catalog_no/AT3753a_S100A13_mo...

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Immunohistochemistry : S100A13 - R&D Systems
Detection of S100A13 in cryostat sections of 13 d.p.c. mouse embryo using 15 µg/ mL of R&D Systems goat anti-mouse S100A13 polyclonal antibody (Catalog ...
http://www.rndsystems.com/ihc_molecule_images.aspx?m=3629...

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Human S100A13 | MBL International
The cDNA of human and murine S100A13 was first identified by screening expressed sequence tag data bases. The human S100A13 was shown to neighbor S100A1 on ...
http://www.mblintl.com/product/cy-r2263...

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S100A13 - R&D Systems
S100A13 is an 11 kDa member of the S100 (soluble in 100% saturated ammonium sulfate) family of vertebrate EF-hand Ca2+-binding proteins. ...
http://www.rndsystems.com/molecule_detail.aspx?m=3629...

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Lab Vision Corporation, a part of Thermo Fisher Scientific
Description: The S100A4 protein belongs to the S100 subfamily, now designated S100A1 – S100A13. This antibody does not cross react with other S100 proteins.
...
http://www.labvision.com/abivd.cfm?first=AntiBody&second=180...

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Recombinant Human S100A13
proteins, S100A13 is small and generally acidic, but contains a basic residuerich sequence at the C ... including S100A13, are able to bind the cell
surface ...
http://www.rndsystems.com/pdf/4327-SA.pdf...

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S100 A4 Ab-8
S100A13. This antibody does not cross react with other S100 proteins. Anti- S100A4 labels fibroblasts, neuronal structures, T-lymphocytes, plasma cells and
...
http://www.labvision.com/pdf/1804.pdf...

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