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S100P


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Symbol:S100P
Name(s):S100 calcium binding protein P
Type:protein-coding
Organism:Homo sapiens
Synonyms:MIG9
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18162774 S100P and pVHL are a pair of sensitive and specific markers for identifying primary pancreatic ductal adenocarcinoma and pancreatic intraepithelial neoplasia
17875703 Overexpression of S100P leads to increased expression of another early pancreatic cancer marker, S100A6, as well as the aspartic protease cathepsin D, both of which are involved in cellular invasion.
17486081 Hypomethylation of wingless-related MMTV integration site 5A (WNT5A), S100 calcium-binding protein P (S100P) and cysteine-rich protein 1(CRIP1) was confirmed in the cancer cells by bisulfite sequencing.
17539915 High S100P expression in ovarian neoplasms obtained after chemotherapy characterize the worse prognosis.
17000674 S100P may be an early developmental marker of pancreatic carcinogenesis, and measurement of S100P in pancreatic juice may be useful for early detection of pancreatic cancer or screening of early pancreatic carcinogenesis.
16047742 results suggest that S100P gene expression is independent of human papillomavirus oncogene protein E7 in cervical carcinoma cell lines and that at least in some cases it is subjected to regulation by DNA methylation
14716296 S100P is identified as a novel DNA hypomethylation target in pancreatic neoplasms.
15632002 can be added to the genetic progression model for pancreatic ductal adenocarcinoma.
14617629 data suggest that S100P can act in an autocrine manner via RAGE to stimulate cell proliferation and survival
14672411 Results describe the cloning of the 1297 bp full-length cDNA, and the characterization of the tissue-specific expression of the human S100P gene.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDadvanced glycosylation end product-specific receptor isoform 1 precursorS100 calcium binding protein P--Pubmed
HPRDadvanced glycosylation end product-specific receptor isoform 1 precursorS100 calcium binding protein P--Pubmed
HPRDS100 calcium binding protein Pcalcyclin binding protein isoform 1--Pubmed
HPRDS100 calcium binding protein PSiah1 interacting protein--Pubmed
HPRDS100 calcium binding protein Pezrin--Pubmed
HPRDS100 calcium binding protein Pezrin--Pubmed
HPRDS100 calcium binding protein PS100 calcium binding protein P--Pubmed
HPRDS100 calcium binding protein Psuppressor of S. cerevisiae gcr2--Pubmed
HPRDS100 calcium binding protein PS100 calcium binding protein Z--Pubmed

Recent Publications on S100P:

Pubmed Logo
Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of GSTP1 in human prostate cancer cells.
Epigenetic silencing of gluthathione-S-transferase pi (GSTP1) is...
27th October, 2009
Department of Urology, Case Western Reserve University & University Int J Cancer. 2009 Oct 23.
DOI Direct Link
The metastasis-associated anterior gradient 2 protein is correlated with poor survival of breast cancer patients.
The secreted metastasis-inducing protein, human anterior gradient 2...
17th October, 2009
Cancer Tissue Bank Research Centre, University of Liverpool, UK. Am J Pathol. 2009 Nov;175(5):1848-57. Epub 2009 Oct 15.
DOI Direct Link
Saliva as a tool for oral cancer diagnosis and prognosis.
Saliva testing, a non-invasive alternative to serum testing, may be an...
16th October, 2009
Department of Oral and Maxillofacial Surgery and Oral Biochemistry Oral Oncol. 2009 Oct 12.
DOI Direct Link
Calcium-binding protein S100P is highly expressed during the implantation window in human endometrium.
OBJECTIVE: To investigate S100P expression and localization in human...
3rd October, 2009
Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Fertil Steril. 2009 Sep 29.
DOI Direct Link
Immutable functional attributes of histologic grade revealed by context-independent gene expression in primary breast cancer cells.
Inherent cancer phenotypes that are independent of fluctuating cross-talk...
1st October, 2009
California Pacific Medical Center Research Institute, San Francisco, Cancer Res. 2009 Oct 1;69(19):7826-34. Epub 2009 Sep 29.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7611839 Methods for diagnosing RCC and other solid tumors
6866993 MDA-9 and uses thereof
6750015 Progesterone receptor-regulated gene expression and methods related thereto
6673545 Prostate cancer markers
6566130 Androgen-regulated gene expressed in prostate tissue

View more patents.

S100P results (if any) from reagent suppliers

Google CSE Logo
S100P antibody (ab42288) | Abcam
Rabbit polyclonal to S100P. S100 proteins are low molecular weight calcium- binding proteins containing the EF-hand motif which are apparently involved in
...
http://www.abcam.com/S100P-antibody-ab42288.html...

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Immunohistochemistry : S100P - R&D Systems
This antibody specifically recognizes human S100P. This antibody has not yet been tested in other species. This antibody can be used for ...
http://www.rndsystems.com/ihc_molecule_images.aspx?m=2886...

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S100P antibodies: Cancer > Tumor biomarkers > Other | Abcam
S100P antibodies. ... Image Abreview Publication. ab42288 · S100P antibody. Fast Track. Images. Rabbit polyclonal. Predicted: ...
http://www.abcam.com/index.html?t=176775&pt=1&c=4375&ei=&mu=...

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BioVendor R&D - Molecules \ S100P
S100P was originally described as a placental protein of 95 amino acid residues shares about 50% sequence identity with the brain S100 proteins alpha and ...
http://www.biovendor.com/molecule/s100p...

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S100P - R&D Systems
Human S100P is a 22 kDa, homodimeric member of the S100 family of calcium- binding proteins. The S100 family currently has more than 20 members and belongs
...
http://www.rndsystems.com/molecule_detail.aspx?m=2886...

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S100 antibody, S100 [4C4.9] Antibody, Mouse Monoclonal Antibody
S100 [4C4.9] interacts with S100P Human, Protein (GenWay Catalog #: 20-272- 192567). SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of ...
http://www.genwaybio.com/product_info.php?products_id=192567...

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Cytokeratin 8 antibody [M20] (ab9023) | Abcam
The role of S100P in the invasion of pancreatic cancer cells is mediated through cytoskeletal changes and regulation of cathepsin D. Cancer Res 67:8633-42 ...
http://www.abcam.com/Cytokeratin-8-antibody-M20-ab9023.html...

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