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SAA2


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Gene DB Home
Symbol:SAA2
Name(s):serum amyloid A2
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15170927 Observational study of gene-disease association. (HuGE Navigator)
16152805 Observational study of genotype prevalence. (HuGE Navigator)
15170927 SAA1a/a genotype is one genetic factor that confers a significant risk for amyloidosis in the Turkish FMF population but neither SAA1 nor SAA2 genotypes had a significant effect on SAA level.
16737350 Increased expression of SAA2 by adipocytes in obesity may play a critical role in local and systemic inflammation and free fatty acid production and could be a direct link between obesity and its comorbidities.
14871291 saa2 is regulated by tumor necrosis factor-alpha, interleukin-6, and glucocorticoids in hepatic and epithelial cells.
12077270 The glucocorticoid response element of the SAA2 promoter is dysfunctional compared to that of SAA1, hence glucocorticoids are unable to enhance the cytokine-driven transcriptional activity of SAA2.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDserum amyloid A2serum amyloid A2--Pubmed

Recent Publications on SAA2:

Pubmed Logo
Gene and protein expression pilot profiling and biomarkers in an experimental mouse model of hypertensive glaucoma.
Glaucoma is a group of genetically heterogeneous neurodegenerative...
11th September, 2009
Duke University Medical Center, Erwin Rd, DUEC 3802, Durham, NC 27710, Exp Biol Med (Maywood). 2009 Aug;234(8):918-30. Epub 2009 Jun 2.
DOI Direct Link
Plasma biomarkers in a mouse model of preterm labor.
Preterm labor (PTL) is frequently associated with inflammation. We...
10th September, 2009
Department of Pediatrics, Stanford University, Stanford, CA 94305, USA. Pediatr Res. 2009 Jul;66(1):11-6.
DOI Direct Link
Association of genetic variation in serum amyloid-A with cardiovascular disease and interactions with IL6, IL1RN, IL1beta and TNF genes in the Cardiovascular Health Study.
AIM: Since inflammation is an important contributor to atherosclerosis,...
5th September, 2009
Department of Epidemiology, University of Washington, WA, USA. J Atheroscler Thromb. 2009 Aug;16(4):419-30. Epub 2009 Sep 3.
Resistance exercise-induced changes of inflammatory gene expression within human skeletal muscle.
Aberrant local inflammatory signaling within skeletal muscle is now...
12th August, 2009
Division of Medicine, Department of Aging and Geriatric Research, Eur J Appl Physiol. 2009 Nov;107(4):463-71. Epub 2009 Aug 11.
DOI Direct Link
Identification in milk of a serum amyloid A peptide chemoattractant for B lymphoblasts.
BACKGROUND: Normal mammary gland contains an extravascular population of B...
13th March, 2009
Institut National de la Recherche Agronomique, UR1282, Infectiologie BMC Immunol. 2009 Jan 23;10:4.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
5151583 Focus adjustment device having restricting means for restricting a selecting action according to the degree of nearness of a distance measurement
6194163 Method for the quantitative measurement of human acute phase serum amyloid A protein; recombinant protein; specific antibody
6198151 Semiconductor device, semiconductor integrated circuit device, and method of manufacturing same
6233195 Multi-bank DRAM suitable for integration with processor on common semiconductor chip
6314045 Semiconductor memory device with a plurality of memory blocks

View more patents.

SAA2 results (if any) from reagent suppliers

Google CSE Logo
SAA (H-84) Antibody sc-20651
Mouse, Saa2, 20209, 7 B4, P05367, N/A. Mouse, Saa3, 20210, 7 B4, P04918, N/A. Mouse, Saa4, 20211, 7 B4, P31532, N/A. Ordering Information ...
http://www.scbt.com/datasheet-20651-saa-h-84-antibody.html...

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MONOCLONAL ANTIBODY TO HUMAN SERUM AMYLOID A-1 (SAA-1)
phase SAA1 and SAA2, the former being the major component in plasma, and constitutive SAAs (C-. SAAs). Although the liver is the primary site of
synthesis ...
http://www.hbt.nl/HM2100.pdf...

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SAA (SAA15) Antibody sc-52215
Human, SAA2, 6289, 11p15.1, NM_030754 · NP_110381 · 104751. Ordering Information . Product Name, Catalog #, Unit, Price, Qty, Wish List ...
http://www.scbt.com/datasheet-52215-saa-saa15-antibody.html...

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Serum Amyloid A antibody [115] (ab687) | Abcam
The serum amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute phase SAA1 and SAA2, the former being a major component ...
http://www.abcam.com/Serum-Amyloid-A-antibody-115-ab687.html...

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SAA (585) Antibody sc-69669
Human, SAA2, 6289, 11p15.1, NM_030754 · NP_110381 · 104751. Ordering Information . Product Name, Catalog #, Unit, Price, Qty, Wish List. SAA (585), sc-69669 ...
http://www.scbt.com/datasheet-69669-saa-585-antibody.html...

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Human SAA Enzyme Immunoassay
SAA genes are located on chromosome 11p.1 SAA1 and SAA2 are similar genes, which differ by 7 amino acids or more, and encode acute-phase SAA's. SAA3 ...
http://abazyme.com/ELISA_Kits_Abazyme//Human%20SAA%20ELISA%2...

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SAA (H-84) Antibody sc-20651
Souris, Saa2, 20209, 7 B4, P05367, Non disponible. Souris, Saa3, 20210, 7 B4, P04918, Non disponible. Souris, Saa4, 20211, 7 B4, P31532, Non disponible ...
http://www.scbt.com/fr/datasheet-20651-saa-h-84-antibody.htm...

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