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SAG


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Gene DB Home
Symbol:SAG
Name(s):S-antigen; retina and pineal gland (arrestin)
Type:protein-coding
Organism:Homo sapiens
Synonyms:ARRESTIN, DKFZp686I1383
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18175313 two models of interaction for the human S-arrestin/rhodopsin complex
17680991 Arrestin in all conformations binds JNK3 comparably, whereas Mdm2 preferentially binds cone arrestin 'frozen' in the basal state.
15295660 Mutation 926delA of the SAG gene is the main cause of Oguchi disease in Japanese. This mutation appears to have been inherited from a single founder.
16481288 SDS-PAGE showed that the expressed arresten proteins were mainly inclusion bodies and had a molecular weight of 26 kDa. The expressed arresten protein showed evident biological activities.
15713799 studies suggest that IRBP and S-Ag can initiate innate and, in sensitive individuals, adaptive immune response by attracting iDCs and T and B cells expressing CXCR3 and CXCR5
17332750 The tetramer form of arrestin increases the arrestin-binding capacity of microtubules while readily dissociating to supply active monomer when it is needed to quench rhodopsin signaling.
15232620 Rhodopsin-arrestin complexes alter the morphology of endosomal compartments and severely damage receptor-mediated endocytic functions in retinitis pigmentosa.
12824223 The light-dependent translocation of cone arrestin suggests a role in light-dark adaptation of cones.
15234147 The existence of 2 novel mutations of the arrestin gene in 2 unrelated Japanese patients strongly supports the previous data that arrestin gene mutations are associated with Oguchi's disease

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDalpha-1B-adrenergic receptorS-arrestin--Pubmed
HPRDalpha-1B-adrenergic receptorS-arrestin--Pubmed
HPRDcholinergic receptor, muscarinic 2S-arrestin--Pubmed
HPRDcholinergic receptor, muscarinic 2S-arrestin--Pubmed
HPRDRhodopsinS-arrestin--Pubmed
HPRDrhodopsinArrestin--Pubmed

Recent Publications on SAG:

Pubmed Logo
Storage of whole blood overnight in different blood bags preceding preparation of blood components: in vitro effects on red blood cells.
BACKGROUND: Routines for the storage of whole blood (WB) overnight for the...
21st October, 2009
Karolinska University Hospital and Karolinska Institutet, Stockholm, Blood Transfus. 2009 Jul;7(3):210-5.
DOI Direct Link
Microbicides development programme: engaging the community in the standard of care debate in a vaginal microbicide trial in Mwanza, Tanzania.
BACKGROUND: HIV prevention research in resource-limited countries is...
10th October, 2009
London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E BMC Med Ethics. 2009 Oct 9;10:17.
DOI Direct Link
Remarks on identification of amplified fragment length polymorphisms linked to SAG resistance in Leishmania.
BACKGROUND: HIV prevention research in resource-limited countries is...
6th October, 2009
Department of Parasitology, Institute of Tropical Medicine Antwerp, Acta Trop. 2009 Oct 2.
DOI Direct Link
Active optics for high-dynamic variable curvature mirrors.
Variable curvature mirrors of large amplitude are designed by using finite...
2nd October, 2009
Opt Lett. 2009 Oct 1;34(19):3009-11. doi: 10.1364/OL.34.003009.
Interaction between superantigen and T-cell receptor Vbeta element determines levels of superantigen-dependent cell-mediated cytotoxicity of CD8(+) T cells in induction and effector phases.
Specific superantigens activate different T-cell fractions with distinct...
25th September, 2009
Department of Microbiology and Immunology, Tokyo Women's Medical Microbiol Immunol. 2009 Aug;53(8):451-9.
DOI Direct Link

View more research publications.

Press Releases on SAG:

BioPortfolio Logo
New Tools to Assist Military Families and Teens Through Difficult Transitions Launched Today by Partnership for a Drug-Free America 30th September, 2009 Partnership for a Drug-Free America

Senator Claire McCaskill Introduces New Resources at Capitol Hill Briefing

NEW YORK, Sept. 30 /PRNewswire-USNewswire/ -- The Partnership for a Drug-Free America(R),

Partnership for a Drug-Free America to Host 'A Traves Del Cristal Meth' Community Program 9th June, 2009 Partnership for a Drug-Free America

WHAT: Representatives from the Partnership for a Drug-Free America (PDFA) will host a presentation of 'A traves del Cristal Meth' (On the Other Side of Crystal Meth), a Spanish

MetLife Foundation Begins new Phase of Award-Winning Parenting Skills Campaign in Collaboration With the Partnership for a Drug-Free America(R) 13th October, 2008 Partnership for a Drug-Free America

NEW YORK, Oct. 13 /PRNewswire/ -- MetLife Foundation will begin the next phase of its award-winning parenting skills campaign, airing educational messages created in cooperation with the

BioNews Results for SAG

: RSS Logo
BioPortfolio Logo
Agilent's Sagging Q4 Bioanalytical Sales Include 7 Percent Dip in Life Science Revenues
GenomeWeb:  Nov 13 2009 9:54PM Matching: sag
Dermatologists Offer Advice From Head To Toe On What To Expect When You're Aging
Medical News Today:  Nov 11 2009 6:17PM Matching: sag
Knee Splint's Multi-Compartment Technology Speeds Rehabilitation from Injuries -- Cost-Effective PKS Cryo's(TM) Individual Chambers Eliminate Migrati
Yahoo! Canada:  Nov 11 2009 3:56PM Matching: sag
Medical News: Dermatologists Offer Advice From Head To Toe On What To Expect When You're Aging
BioFind:  Nov 11 2009 3:11PM Matching: sag
Tips for treating age-related dermatologic concerns
News-Medical.Net:  Nov 11 2009 8:40AM Matching: sag
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Adefovir Dipivoxil In Compensated Chronic Hepatitis B Patients

Patents:

Patents logo
US Patent No.Title
7601219 Apparatus for ejecting liquid droplet, work to be applied thereto, method of manufacturing electro-optic device, electro-optic device, and electronic equipment
7604775 Fluid collecting and monitoring device
7604783 Reduction of lime consumption when treating refractor gold ores or concentrates
7604832 Film forming method, film forming apparatus, pattern forming method, and manufacturing method of semiconductor apparatus
7605097 Fiber-containing composite and method for making the same

View more patents.

SAG results (if any) from reagent suppliers

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Hep B sAg (1023) Antibody sc-53299
mouse monoclonal IgG1, 200µg/ml; raised against recombinant Hep B sAg ... Hep B sAg (1023): sc-53299. Western blot analysis of recombinant hepatitis B ...
http://www.scbt.com/datasheet-53299-hep-b-sag-1023-antibody....

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Monoclonal Antibodies to Viruses and Microbial Agents - Advanced ...
Plasmodium falciparum S-antigen (Sag), antibody. Description: Plasmodium falciparum S-antigen (Sag), antibody. &n… New ...
http://www.advimmuno.com/monoclonal-antibodies-to-viruses-an...

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Hep B sAg (3E7) Antibody sc-57785
Hep B sAg (3E7) Antibody sc-57785 Hep B sAg (3E7) Antibody sc-57785.
http://www.scbt.com/datasheet-57785-hep-b-sag-3e7-antibody.h...

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SAG - Enzo Life Sciences
SAG,,Signal Transduction,Hedgehog [Hh] Signalling Pathway,
http://www.enzolifesciences.com/ALX-270-426/sag/...

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Hep B sAg (1861) Antibody sc-58142
mouse monoclonal IgG2a, 100µg/ml; raised against Hep B sAg; recommended for detection of subtypes ad and ay of surface antigen of Hep B origin by solid ...
http://www.scbt.com/datasheet-58142-hep-b-sag-1861-antibody....

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Anti-Hepatitis B Virus Surface Antigen Monoclonal Antibody
The MA1-7350 antibody reacts with Hepatitis B virus sAg. probe in viral and infected tissue samples. MA1-7350 has been successfully used in ELISA ...
http://www.bioreagents.com/products/productDetails/productDe...

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Hepatitis B Protein Antibody / Hepatitis B Protein Antibodies
Hep B sAg (1821) Antibody, sc-65455, mouse IgG2a, FL (v), ELISA, Hep B ... Hep B sAg (86C) Antibody, sc-57786, mouse IgG1, FL (v), WB, Hep B ...
http://www.scbt.com/table-hepatitis_b_protein.html...

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