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SERPINB3
| Symbol: | SERPINB3 | | Name(s): | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, T4-A | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 14970861 |
SCCA variants are overexpressed in hepatocellular carcinoma independently of tumour etiology; a novel SCCA1 variant has been identified in one third of liver tumours |
| 16701102 |
SCC-Ag mRNA levels in the peripheral blood are the best predictive factor for recurrence in patients with esophageal squamous cell carcinoma who undergo curative resection. |
| 15902720 |
the hydrophobicity of the reactive site loop of SCCA1 may play an important role in hepatitis B virus binding to cells |
| 16681421 |
squamous cell carcinoma antigen is expressed in peripheral blood of cancer patients |
| 12773976 |
concentration and the positivity rate significantly elevated with esophageal squamous cell tumor progression; differences depended on tumor size, tumor depth, lymph node status, and distant metastasis |
| 14654899 |
Findings suggest that genetic diagnosis by RT-PCR based on SCCA mRNA expression may be clinically useful for detecting occult tumor cells in cervical lymph nodes. |
| 15733534 |
Single nucleotide polymorphism of SCCA2 indicated that this polymorphism may underlie the difference in promoter activity between SCCA1 and SCCA2. |
| 17523076 |
The expression pattern of SCCA1 in esophageal dysplasia and squamous cell carcinmoma was studied. |
| 12975381 |
transfection of SCCA1 into mammalian cells (both hepatocyte-derived and of non-hepatocyte origin) results in increased HBV binding |
| 14719077 |
E-cadherin mediated cell-cell adhesion maintains SCCA production through PI 3-kinase in squamous cell carcinoma. | →View more information from publications. |
Recent Publications on SERPINB3: |  |
The nutrigenomics of asthma: molecular mechanisms of airway neutrophilia following dietary antioxidant withdrawal.
Depletion of antioxidants through consumption of a low antioxidant diet... | 1st September, 2009
| Priority Research Centre for Asthma and Respiratory Diseases, University
| OMICS. 2009 Oct;13(5):355-65.
DOI Direct Link |
STAT6 activation by Toxoplasma gondii infection induces the expression of Th2 C-C chemokine ligands and B clade serine protease inhibitors in macrophage.
Toxoplasma gondii provoked rapid and sustained nuclear translocation of... | 6th August, 2009
| Department of Parasitology and the Catholic Institute of Parasitic
| Parasitol Res. 2009 Oct;105(5):1445-53. Epub 2009 Aug 5.
DOI Direct Link |
Squamous cell carcinoma antigen-1 (SERPINB3) polymorphism in chronic liver disease.
BACKGROUND: The serpin squamous cell carcinoma antigen (SCCA, SERPINB3)... | 29th May, 2009
| Department of Clinical and Experimental Medicine, University of Padua,
| Dig Liver Dis. 2009 Mar;41(3):212-6. Epub 2008 Jul 25.
DOI Direct Link |
SERPINB3, apoptosis and autoimmunity.
SERPINB3 (Squamous Cell Carcinoma Antigen, SCCA1) is a member of the... | 1st April, 2009
| Clinica Medica 5, Department of Clinical and Experimental Medicine,
| Autoimmun Rev. 2009 Dec;9(2):108-12. Epub 2009 Mar 27.
DOI Direct Link |
Comparison of expression profiles induced by dust mite in airway epithelia reveals a common pathway.
BACKGROUND: Airway epithelial cells have shown to be active participants... | 16th April, 2008
| Department of Otorhinolaryngology, Academic Medical Center, Amsterdam, The
| Allergy. 2008 Apr;63(4):461-7.
DOI Direct Link |
→View more research publications. |
SERPINB3 results (if any) from reagent suppliers |
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SerpinB3 antibody (ab55733) | Abcam
Mouse monoclonal to SerpinB3. SerpinB3 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins. It was first discovered as a protein ...
http://www.abcam.com/SerpinB3-antibody-ab55733.html...
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SCCA1 (8H11) Antibody sc-21767
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, SERPINB3, 6317, 18q21.33, NM_006919 ...
http://www.scbt.com/datasheet-21767-scca1-8h11-antibody.html...
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SerpinB3 antibody - Amino end mature SCCA-1 (ab47726) | Abcam
Rabbit polyclonal to SerpinB3 - Amino end mature SCCA-1. SerpinB3 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins.
http://www.abcam.com/SerpinB3-antibody-Amino-end-mature-SCCA...
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SPB3 Antibody (N-term)
Serpin B3; Squamous cell carcinoma antigen 1; SCCA-1; Protein T4-A; SCCA1; SCCA; SERPINB3. Application Data: Calculated MW: 44565 Da ...
http://www.abgent.com/products/catalog_no/AP6579a_SPB3_Antib...
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SCCA1 (8H11) Antibody sc-21767
... Numéro d'accès d´isoforme d´ARNm, Numéro d'accès de la protéine, Numéro OMIM ™. Humain, SERPINB3, 6317, 18q21.33, NM_006919 · P29508 ...
http://www.scbt.com/fr/datasheet-21767-scca1-8h11-antibody.h...
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Cell Biology: primary antibodies, proteins, peptides, kits | Abcam
... SERPINI2 proteins and peptides (1) · SerpinB11 antibodies (1) · SerpinB2 antibodies (2) · SerpinB2 proteins and peptides (1) · SerpinB3 antibodies (2) ...
http://www.abcam.com/index.html?cl=246&pageconfig=productmap...
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SCCA1 (8H11) Antibody sc-21767
种属, 基因名称, 基因ID, 染色质位置, 亚型(mRNA)即位号码, 蛋白质即位号码, OMIM™ 号码. 人类, SERPINB3, 6317, 18q21.33, NM_006919 · P29508 ...
http://www.scbt.com/zh/datasheet-21767-scca1-8h11-antibody.h...
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