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XCL1
| Symbol: | XCL1 | | Name(s): | chemokine (C motif) ligand 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCYC1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 12847680 |
Lptn might be a key modulator for T cell trafficking in the pathogenesis of rheumatoid arthritis |
| 12053063 |
lymphotactin, as well as MCP-1, may contribute to leukocyte infiltration and disease progression in IgA nephropathy. |
| 14568926 |
In humans XCL1 expression is mainly a property of CD8+ T cells; the contribution to its synthesis by different T cell receptor alpha beta-expressing T cell subsets, namely CD4+ lymphocytes, is negligible. |
| 12393716 |
Lymphotactin, (MIP)-1alpha, and MIP-1beta chemokines were all rapidly induced by engagement of CD28 and were calcineurin sensitive. |
| 14734774 |
XCL1 activation is positively correlated with HIV-1 Tat expression in human U87.MG astrocytes in vitro. |
| 14707146 |
lymphotactin utilizes highly specific glycosaminoglycan-binding sites |
| 11889129 |
NMR spectra of human lymphotactin (hLtn), obtained under various solution conditions, have revealed that the protein undergoes a major conformational rearrangement dependent on temperature and salt concentration. |
| 16923584 |
description of a lymphotactin-producing monoclonal T-cell lymphoproliferative disorder with extreme lymphocytopenia and progressive leukoencephalopathy [case report] |
Recent Publications on XCL1: |  |
I-TAC is a dominant chemokine in controlling skin intragraft inflammation via recruiting CXCR3(+) cells into the graft.
Chemokines play a critical role in the acute transplant rejection. In... | 31st October, 2009
| Department of Immunology, Institute for Immunobiology, Shanghai Medical
| Cell Immunol. 2009 Sep 11.
DOI Direct Link |
Dendritic cell-based vaccines for pancreatic cancer and melanoma.
Based on leads from our recent animal studies, we are embarking on a... | 24th October, 2009
| Moffitt Cancer
| Ann N Y Acad Sci. 2009 Sep;1174:33-40.
DOI Direct Link |
Expression and Function of the C-Class Chemokine Lymphotactin (XCL1) in Wegener's Granulomatosis.
OBJECTIVE: In Wegener's granulomatosis (WG), vasculitic lesions are... | 3rd October, 2009
| From the Department of Nephrology and Rheumatology, University of
| J Rheumatol. 2009 Oct 1.
DOI Direct Link |
Chapter 3. Lymphotactin structural dynamics.
Lymphotactin/XCL1, the defining member of the C class of chemokines,... | 21st August, 2009
| Department of Biochemistry, Medical College of Wisconsin, Milwaukee,
| Methods Enzymol. 2009;461:51-70.
DOI Direct Link |
miRNA expression profiles in head and neck squamous cell carcinoma and adjacent normal tissue.
BACKGROUND: The expression of miRNA in head and neck squamous cell... | 21st August, 2009
| Department of Experimental Radiation Oncology, The University of Texas MD
| Head Neck. 2009 May;31(5):642-54.
DOI Direct Link |
→View more research publications. |
XCL1 results (if any) from reagent suppliers | 
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mouse XCL1 antibody, Affinity Purified conjugate
eBioscience technical data sheet for product 14-7997 Polyclonal anti-mouse XCL1 (Lymphotactin/SCM-1a) Polyclonal antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_14/14-...
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ORDERING INFORMATION
secondary reagents to detect human XCL1. The detection limit for rhXCL1 is ... XCL1 ELISA in combination with biotinylated, human XCL1 affinity purified ...
http://www.rndsystems.com/pdf/mab6951.pdf...
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Antibodies to Chemokines
Xcl1(16963), mouse, ELISA (i), Neutral, WB, pricing. M256, Anti-Macrophage Inflammatory Protein-1α antibody produced in goat, (polyclonal) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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mouse XCL1/Lymphotactin DuoSet
XCL1/Lymphotactin. Catalog Number: DY486. This DuoSet ELISA Development kit contains the basic components required for the development of ...
http://www.rndsystems.com/pdf/dy486.pdf...
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Anti-Lymphotactin antibody produced in goat (L1165) - Datasheet
Mouse lymphotactin (Lptn)/XCL1 and its human homologue (also named human SCM-1 and ATAC), members of the γ or C subfamily of chemokines, are ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/datashee...
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Recombinant Human XCL1/Lymphotactin
Human lymphotactin (Lptn)/XCL1 (also named human SCM1α and ATAC) and its mouse homologue belong to the C or γ subfamily of chemokines. The ...
http://www.rndsystems.com/pdf/695-lt.pdf...
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MAP-2 (D-19) Antibody sc-5359
Induction of C chemokine XCL1 (lymphotactin/single C motif-1alpha/activation- induced, T cell-derived and chemokine-related cytokine) expression by HIV-1 Tat
...
http://www.scbt.com/datasheet-5359-map-2-d-19-antibody.html...
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