Monday November 23 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

BLM


Suggest Content
Advertise Here
Gene DB Home
Symbol:BLM
Name(s):Bloom syndrome
Type:protein-coding
Organism:Homo sapiens
Synonyms:BS, MGC126616, MGC131618, MGC131620, RECQ2, RECQL2, RECQL3
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16412221 if a DNA oligomer complementary to one strand of the DNA substrate to be unwound is added during the helicase reaction, both WRN and BLM unwinding is enhanced, presumably by preventing protein-mediated re-annealing
17984114 BLM enhances the interaction and co-localization between 53BP1 and RAD51 during replication arrest
18264947 Observational study of genotype prevalence. (HuGE Navigator)
18270339 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
11876000 Observational study of genotype prevalence. (HuGE Navigator)
12702560 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15726604 Observational study of genotype prevalence. (HuGE Navigator)
15959913 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17961633 human SUV3 protein interacts with human BLM helicase.
17943968 Loss of function suppresses mismatch repair mutator mechanism.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDBLMtumor protein p53--Pubmed
HPRDBLMWerner syndrome protein--Pubmed
HPRDBLMmyxovirus resistance protein 1--Pubmed
HPRDBLMRAD51 homolog protein isoform 1--Pubmed
HPRDBLMRAD51-like 3 isoform 1--Pubmed
HPRDRecQ protein like 3RAD51-like 3 isoform 1--Pubmed
HPRDBLMtopoisomerase III alpha--Pubmed
HPRDBLMtelomeric repeat binding factor 2--Pubmed
HPRDBloom syndrome proteinTopoisomerase DNA III alpha--Pubmed
HPRDBloom syndrome proteinRAD51--Pubmed

Recent Publications on BLM:

Pubmed Logo
[Effect of Huzhang on expression of lung fibroblasts' MMP-2/TIMP-1mRNA in pulmonary fibrosis rats]
OBJECTIVE: To observe the effect of Huzhang on the progress of pulmonary...
14th October, 2009
The Second Hospital, College of Medicine, Zhejiang University, Hangzhou Zhongguo Zhong Yao Za Zhi. 2009 Jun;34(12):1574-7.
Spontaneous and bleomycin-induced chromosome damage in non cancer thyroid patients.
Eur J Clin Invest 2009Abstract Background Presence of chromosome damage in...
8th October, 2009
University of Pisa, Pisa, Italy. Eur J Clin Invest. 2009 Oct 6.
DOI Direct Link
Free-Standing Lipid Bilayers in Silicon Chips-Membrane Stabilization Based on Microfabricated Apertures with a Nanometer-Scale Smoothness.
In the present study, we propose a method for preparing stable...
6th October, 2009
Graduate School of Biomedical Engineering, Tohoku University, 6-6 Aoba, Langmuir. 2009 Oct 2.
DOI Direct Link
Inhibition of renal Na+-ATPase activity by inosine is mediated by A1 receptor-induced inhibition of the cAMP signaling pathway.
We have previously demonstrated that adenosine is deaminated to inosine in...
30th September, 2009
Instituto de Biofisica Carlos Chagas Filho, Universidade Federal do Rio de Arch Biochem Biophys. 2009 Sep;489(1-2):76-81. Epub 2009 Jul 12.
DOI Direct Link
PKC{alpha}{beta}{gamma}- and PKC{delta}-dependent endocytosis of NBCe1-A and NBCe1-B in salivary parotid acinar cells.
We examined membrane trafficking of NBCe1-A and NBCe1-B variants of the...
29th September, 2009
1University of Colorado and Denver Health Sciences Center. Am J Physiol Cell Physiol. 2009 Sep 30.
DOI Direct Link

View more research publications.

Press Releases on BLM:

BioPortfolio Logo
Aptilon Announces Acquisition of Direct Medical Data, LLC and BLM Incorporated and Concurrent Private Placements 18th September, 2009 APTILON CORPORATION

MONTREAL, Sept. 18 /PRNewswire-FirstCall/ - Aptilon Corporation ("Aptilon" or the "Corporation") (TSX-V: APZ), a leading provider of physician access through its innovative

BioNews Results for BLM

: RSS Logo
BioPortfolio Logo
New cancer gene therapy research has been reported by H. Maeda et al
Pharmacy Choice:  Oct 12 2009 9:47PM Matching: blm

Clinical Trials:

Clinical Trials Logo
Japan Phase 2/3 Clinical Study With BLM-240 (Desflurane)

Patents:

Patents logo
US Patent No.Title
7544358 Treatment of acute lung injury, fibrosis and metastasis with antagonists of .alpha.v.beta.6
7554859 Nonvolatile memory system and associated programming methods
7558148 Memory controller
7560320 Nonvolatile semiconductor memory and a fabrication method for the same
7560724 Storage device with reversible resistance change elements

View more patents.

BLM results (if any) from reagent suppliers

Google CSE Logo
BLM Antibody / BLM Antibodies
The gene responsible for Bloom's syndrome, BLM, encodes a protein homologous to the RecQ helicase of E. coli and is mutated in most Bloom's syndrome ...
http://www.scbt.com/table-blm.html...

Thumbshot
BLM Antibody #2742
BLM, a member of the RecQ family of DNA helicases, is part of the BRCA1- associated genome surveillance complex (BASC) that responds to DNA damage, ...
http://www.cellsignal.com/products/2742.html...

Thumbshot
Blooms Syndrome Protein Blm antibody (ab476) | Abcam
Rabbit polyclonal to Blooms Syndrome Protein Blm (phospho T99) (ab62206) .... Contact Abcam with a Technical Enquiry about Blooms Syndrome Protein Blm ...
http://www.abcam.com/Blooms-Syndrome-Protein-Blm-antibody-ab...

Thumbshot
BLM Antibody
phorylation of BLM helicase at Thr99 and Thr122 occurs in response to genotoxic stress (4), ... in BLM helicase are responsible for development of Bloom ...
http://www.cellsignal.com/pdf/2742.pdf...

Thumbshot
Blooms Syndrome Protein Blm antibody (ab476) reviews | Abcam
In western blot the BLM protein was also well visible although there was quite a lot of ... The Blm antibody worked well for western blotting, where ...
http://www.abcam.com/index.html?pageconfig=reviews&intAbID=4...

Thumbshot
BLM (C-18) Antibody sc-7790
See how others have used BLM (C-18): sc-7790 antibody and or BLM (C-18) antibody conjugates ... The Bloom's syndrome helicase (BLM) interacts physically and ...
http://www.scbt.com/datasheet-7790-blm-c-18-antibody.html...

Thumbshot
Blooms Syndrome Protein Blm antibody [BFL-103] (ab5409) | Abcam
Mouse monoclonal [BFL-103] to Blooms Syndrome Protein Blm. The Bloom's syndrome (BS) gene, BLM, plays an important role in the maintenance of genomic ...
http://www.abcam.com/Blooms-Syndrome-Protein-Blm-antibody-BF...

Thumbshot

Search Bioportfolio and other Life Science Sites for BLM, or search for BLM on BioPortfolio's antibody search engine.
This page has been viewed 238 times
Recent Search Terms used to find this page:
bloom s syndrome genotype | oregon thr122 | 293T and bloom syndrome protein BLM | BLM Bloom | BLM bloom syndrome | BLM shRNA | bloom syndrome genotype | bloom thr99 ab | BLM siRNA | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.