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IFIH1


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Gene DB Home
Symbol:IFIH1
Name(s):interferon induced with helicase C domain 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:Hlcd, IDDM19, MDA-5, MDA5, MGC133047
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18285833 Observational study of gene-disease association. (HuGE Navigator)
16699517 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
17442111 Observational study of gene-disease association. (HuGE Navigator)
17535987 Observational study of gene-disease association. (HuGE Navigator)
18026693 Observational study of gene-disease association. (HuGE Navigator)
18071670 Observational study of gene-disease association. (HuGE Navigator)
18026693 An association of A946T polymorphism of the IFIH1 gene with the development of Graves' disease in a Chinese population was not apparent.
17442111 IFIH1 is upregulated in RA but that the A946T variant does not contribute significantly to the genetic background of RA
17541283 The putative dsRNA receptor MDA-5 may not play a pivotal role in the dsRNA-stimulated expression of inflammatory chemokines in airway epithelial cells.
17535987 we confirm a significant contribution of the IFIH1 polymorphism to organ-specific autoimmune diseases, extending the range of conditions associated with this variant to include Graves' disease

View more information from publications.

Patents:

Patents logo
US Patent No.Title
7608256 Methods to increase transgene expression from bacterial-based delivery systems by co-expressing suppressors of the eukaryotic type I interferon response
7604939 Methods of identifying active BRM expression-promoting HDAC inhibitors

IFIH1 results (if any) from reagent suppliers

Google CSE Logo
MAVS antibody, Rabbit anti VISA (Middle) Antibody, Rabbit ...
Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced ... The CARD domain is responsible for interaction with DDX58 and IFIH1
. ...
http://www.genwaybio.com/product_info.php?products_id=244362...

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MB-MN
SAB2500624, Anti-MDA5/IFIH1 antibody produced in goat New, (polyclonal), affinity isolated antibody, human ... IFIH1(64135), human, ELISA (i), IHC,
pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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MDA5 Antibody (IN) Melanoma differentiation-associated protein 5
Additional Names. MDA5 (IN), Melanoma differentiation-associated protein 5, Interferon-induced with helicase C domain protein 1, IFIH1 ...
http://www.prosci-inc.com/shop/catalog1/MDA5-Antibody-p-6487...

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MDA-5 (R470) Antibody #4110
MDA-5 (16,17), also named Ifih1 (interferon induced with helicase C domain 1), RH116 (RNA helicase-DEAD box protein 116) (18), and Helicard (19) is found to
...
http://www.cellsignal.com/products/4110.html...

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MDA5 Antibody
C domain protein 1, IFIH1. CATALOG No.:4037. BACKGROUND: The innate immune system detects viral infection by recognizing various viral components and ...
http://www.prosci-inc.com/shop/pdf/4037.pdf...

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Enzo Life Sciences: Monoclonal Antibody to Cardif (human) (Adri-1)
RIG-I (retinoic acid-inducible gene I; Ddx58) and MDA5 (melanoma differentiation -associated gene 5, also known as Ifih1 or Helicard) are proteins that sense ...
http://www.enzolifesciences.com/ALX-804-847/monoclonal-antib...

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MDA5 (C-16) Antibody sc-48031
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, IFIH1, 64135, 2q24.2, NM_022168 ...
http://www.scbt.com/ko/datasheet-48031-mda5-c-16-antibody.ht...

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