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SFTPD


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Symbol:SFTPD
Name(s):surfactant, pulmonary-associated protein D
Type:protein-coding
Organism:Homo sapiens
Synonyms:COLEC7, PSP-D, SFTP4, SP-D
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18251786 In lung of patients with pulmonary alveolar proteinosis, SP-D was localized eoosinophilic large globules surrounded by an SP-A positive fine granular substance.
18226251 Further, we speculate that inhaled steroids may induce SP-D expression and that this mechanism may contribute to their beneficial effects in COPD.
17693780 Serum surfactant-protein D (SP-D) concentrations increased in silica-exposed miners and may associate with pathogenesis of and be a useful biomarker for early diagnosis of silicosis.
17083016 Observational study of gene-disease association. (HuGE Navigator)
12032263 Observational study of gene-disease association. (HuGE Navigator)
13680361 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15102713 Observational study of gene-disease association. (HuGE Navigator)
15700120 Observational study of gene-disease association. (HuGE Navigator)
16426259 Observational study of gene-disease association. (HuGE Navigator)
17264398 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDdecorin isoform a preproproteinsurfactant, pulmonary-associated protein D--Pubmed
HPRDdecorin isoform a preproproteinsurfactant, pulmonary-associated protein D--Pubmed
HPRDdeleted in malignant brain tumors 1 isoform b precursorsurfactant, pulmonary-associated protein D--Pubmed
HPRDdeleted in malignant brain tumors 1 isoform b precursorsurfactant, pulmonary-associated protein D--Pubmed
HPRDMicrofibrillar associated protein 4surfactant, pulmonary-associated protein D--Pubmed
HPRDmicrofibrillar-associated protein 4Pulmonary surfactant associated protein D--Pubmed
HPRDsurfactant, pulmonary-associated protein Dsurfactant, pulmonary-associated protein D--Pubmed

Recent Publications on SFTPD:

Pubmed Logo
Novel strategy to identify genetic risk factors for COPD severity: a genetic isolate.
Studies using genetic isolates with limited genetic variation may be...
3rd October, 2009
University Medical Center Groningen, University of Groningen, Groningen, Eur Respir J. 2009 Sep 24.
DOI Direct Link
Association between single nucleotide polymorphisms of surfactant protein D and allergic rhinitis in Chinese patients.
The development of allergic rhinitis is considered to be determined by the...
11th August, 2009
Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Tissue Antigens. 2009 Jun;73(6):546-52.
DOI Direct Link
Genetic variants in surfactant, pulmonary-associated protein D (SFTPD) and Japanese susceptibility to ulcerative colitis.
BACKGROUND: Identifying culprit genes for a complex trait in a homogeneous...
31st July, 2009
First Department of Internal Medicine, Sapporo Medical University, Inflamm Bowel Dis. 2009 Jun;15(6):918-25.
DOI Direct Link
Surfactant protein-D regulates the postnatal maturation of pulmonary surfactant lipid pool sizes.
Surfactant protein (SP)-D plays an important role in host defense and...
12th June, 2009
Div. of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, J Appl Physiol. 2009 May;106(5):1545-52. Epub 2009 Mar 5.
DOI Direct Link
Association of polymorphisms in the human surfactant protein-D (SFTPD) gene and postnatal pulmonary adaptation in the preterm infant.
BACKGROUND: Surfactant protein-D (SP-D) is a member of the collagenous...
3rd April, 2009
Department of Paediatrics, University of Giessen, Giessen, Germany. Acta Paediatr. 2009 Jan;98(1):112-7. Epub 2008 Sep 9.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7514219 Method for distinguishing between head and neck squamous cell carcinoma and lung squamous cell carcinoma
7386510 System and method for detecting fraudulent calls
7291461 Methods for identifying small molecules that modulate premature translation termination and nonsense mRNA decay

View more patents.

SFTPD results (if any) from reagent suppliers

Google CSE Logo
SP-D (12G5) Antibody sc-80622
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, SFTPD, 6441, 10q22.3, NM_003019 ...
http://www.scbt.com/datasheet-80622-sp-d-12g5-antibody.html...

Thumbshot
3C-3E
Monoclonal Anti-SFTPD antibody produced in mouse clone 3E6, purified immunoglobulin, buffered aqueous solution, 3E6 (monoclonal) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

Thumbshot

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