Recent Publications on : |  |
The evolution of gnathostome development: Insight from chondrichthyan embryology.
Chondrichthyans (cartilaginous fishes) represent one of the two lineages...
Direct Link | 3rd November, 2009
| Department of Organismal Biology and Anatomy, University of Chicago,
|
Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway.
The Hedgehog (Hh) signaling pathway plays crucial roles in embryonic...
Direct Link | 3rd November, 2009
| Department of Gene Technology, Tallinn University of Technology, Akadeemia
|
The metalloendopeptidase gene Pitrm1 is regulated by hedgehog signaling in the developing mouse limb and is expressed in muscle progenitors.
Pitrm1 is a zinc metalloendopeptidase that has been implicated in...
Direct Link | 31st October, 2009
| The University of Queensland, Institute for Molecular Bioscience,
|
The molecular basis of oral-facial-digital syndrome, type 1.
Oral-facial-digital syndrome type 1 (OFDI; OFD1; OMIM 311200) is a rare...
Direct Link | 31st October, 2009
|
|
Nuclear factor kappaB-activated monocytes contribute to pancreatic cancer progression through the production of Shh.
Recently, it was reported that Hh signaling is activated in tumor stromal...
Direct Link | 29th October, 2009
| Department of Cancer Therapy and Research, Graduate School of Medical
|
Overexpression of Sonic Hedgehog in the Lung Mimics the Effect of Lung Injury and Compensatory Lung Growth on Pulmonary Sca-1 and CD34 Positive Cells.
Cells localized in the bronchioalveolar duct junction of the murine lung...
Direct Link | 29th October, 2009
| Department of Genetic Medicine, Weill Cornell Medical College, New York,
|
Hedgehog pathway activity is required for the lethality and intestinal phenotypes of mice with hyperactive Wnt signaling.
Several lines of evidence point to the central role of WNT signaling in...
Direct Link | 29th October, 2009
| University of Geneva Medical School Dept. Genetic Medicine and Development
|
| Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.
| 29th October, 2009
| M & M Medical Bioinformatics, Hongo 113-0033, Japan.
|
Distinct expression patterns of hedgehog ligands between cultured and primary colorectal cancers are associated with aberrant methylation of their promoters.
Ligand-dependent activation of the Hedgehog (Hh) pathway in colorectal...
Direct Link | 27th October, 2009
| Department of Gastroenterology, The People's Hospital of Deyang City,
|
Zebrafish zic2a patterns the forebrain through modulation of Hedgehog-activated gene expression.
Holoprosencephaly (HPE) is the most common congenital malformation of the...
Direct Link | 27th October, 2009
| Department of Zoology and Anatomy, University of Wisconsin, Madison, WI
|
A BMP-Shh negative-feedback loop restricts Shh expression during limb development.
Normal patterning of tissues and organs requires the tight restriction of...
Direct Link | 27th October, 2009
| Instituto de Biomedicina y Biotecnologia de Cantabria, Universidad de
|
Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain.
Accumulating evidence suggests that Sonic hedgehog (Shh) signaling plays a...
Direct Link | 27th October, 2009
| Department of Anatomy and Developmental Biology, Yoshida, Sakyo-ku, Kyoto
|
Spatiotemporally separable Shh domains in the midbrain define distinct dopaminergic progenitor pools.
Midbrain dopamine neurons (mDA) are important regulators of diverse...
Direct Link | 24th October, 2009
| Northwestern University Feinberg School of Medicine, Department of
|
Autocrine and paracrine Shh signaling are necessary for tooth morphogenesis, but not tooth replacement in snakes and lizards (Squamata).
Here we study the role of Shh signaling in tooth morphogenesis and...
Direct Link | 24th October, 2009
| Department of Oral Health Sciences, Faculty of Dentistry, University of
|
A specific mutation in the distant sonic hedgehog cis-regulator (ZRS) causes Werner mesomelic syndrome while complete ZRS duplications underlie Haas type polysyndactyly and preaxial polydactyly with or without triphalangeal thumb.
Werner mesomelic syndrome (WMS) is an autosomal dominant disorder with...
Direct Link | 23rd October, 2009
| Institut fur Humangenetik, Universitatsklinikum Essen, Essen, Germany.
|
