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BMI1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18269588 |
Neither EGFR nor BMI-1 had significant prognostic impact for basal-like phenotype of breast cancer. |
| 17711569 |
Elevated Bmi-1 is associated with breast cancer |
| 17625597 |
Bmi-1 may promote maintenance of suprabasal keratinocyte survival to prevent premature death during differentiation. |
| 17974970 |
Examination of various growth-regulatory pathways suggested that Bmi-1 overexpression together with H-Ras promotes human mammary epithelial cell transformation and breast oncogenesis by deregulation of multiple growth-regulatory pathways. |
| 17145814 |
Bmi1 overexpression was correlated with the malignant grades of human digestive precancerous tissues, which suggests that advanced Bmi1 dysregulation might predict malignant progression. |
| 17145810 |
The oncogenic role of Bmi-1 in human primary breast carcinomas is not determined by its capacity to inhibit INK4a/ARF proteins(p16INK4a, p14ARF, or h-TERT) or to induce telomerase activity. |
| 17597110 |
BMI-1 mediated repression of p16(ink4a) may contribute to an increased aggressive behavior of stem cell-like melanoma cells. |
| 17360938 |
In a cohort of 64 CML patients, the level of BMI1 at diagnosis correlated with time to transformation to blast crisis, and the combination of low BMI1 and high proteinase-3 expression was associated with an improved overall survival |
| 17454639 |
Bmi-1 seems to play a secondary role in chronic myeloid leukemia transformation |
| 17134822 |
PcG protein BMI1 is associated with adverse pathological features and clinical PSA recurrence of prostate cancer. | →View more information from publications. |
Recent Publications on BMI1: |  |
Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.
Hedgehog signaling is aberrantly activated in glioma, medulloblastoma,... | 29th October, 2009
| M & M Medical Bioinformatics, Hongo 113-0033, Japan.
| Curr Mol Med. 2009 Sep;9(7):873-86.
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Knockdown of Bmi-1 impairs growth and invasiveness of human gastric carcinoma cells.
The effect of B cell-specific MLV integration site-1 (Bmi-1) RNA... | 23rd October, 2009
| Department of Gastroenterology and Hubei Provincial Center of Clinical
| Oncol Res. 2009;17(11-12):613-20.
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GSK3beta regulates differentiation and growth arrest in glioblastoma.
Cancers are driven by a population of cells with the stem cell properties... | 14th October, 2009
| Laboratory of Molecular Neuro-Oncology, University Hospital Basel, Basel,
| PLoS One. 2009 Oct 13;4(10):e7443.
DOI Direct Link |
Balancing dormant and self-renewing hematopoietic stem cells.
The mouse hematopoietic stem cell (HSC) is probably the best-understood... | 9th October, 2009
| Ludwig Institute for Cancer Research Ltd., Lausanne Branch, University of
| Curr Opin Genet Dev. 2009 Oct 5.
DOI Direct Link |
Diagnostic importance of overexpression of Bmi-1 mRNA in early breast cancers.
Target molecules for a highly sensitive and specific diagnosis of breast... | 2nd October, 2009
| Department of Clinical Laboratory Medicine, Sapporo Medical University
| Int J Oncol. 2009 Sep;35(3):511-5.
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→View more research publications. |
BMI1 results (if any) from reagent suppliers |
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