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ACD


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Symbol:ACD
Name(s):adrenocortical dysplasia homolog (mouse)
Type:protein-coding
Organism:Homo sapiens
Synonyms:PIP1, PTOP, TINT1, TPP1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17466001 Observational study of genotype prevalence. (HuGE Navigator)
17466001 No mutations were identified in ACD in this collection of patients with ACTH resistance phenotypes. However, the newly identified SNPs in ACD should be more closely examined for possible links to disease.
17632522 Tpp1 is required for the protective function of Pot1 proteins.
16504561 Sequencing of ACD in 15 patients with clinical features of IMAGe syndrome, adrenal hypoplasia congenita, or congenital adrenal insufficiency revealed no coding mutations, but three novel SNPs were identified
17373762 REVIEW:TPP1 as a critical mediator of control of telomerase activity
16880378 coordinated interactions among TPP1, TIN2, TRF1, and TRF2 may ensure robust assembly of the telosome, telomere targeting of its subunits, and, ultimately, regulated telomere maintenance
17237767 findings highlight the critical role of TPP1 in telomere maintenance, and support a yin-yang model in which TPP1 and POT1 function as a unit to protect human telomeres, by both positively and negatively regulating telomerase access to telomere DNA
17237768 crystal structure of human TPP1 reveals an oligonucleotide/oligosaccharide-binding fold that is structurally similar to the beta-subunit of the telomere end-binding protein of a ciliated protozoan; TPP1 is the missing beta-subunit of human POT1
17237767 findings highlight the critical role of TPP1 in telomere maintenance, and support a yin-yang model in which TPP1 and POT1 function as a unit to protect human telomeres, by both positively and negatively regulating telomerase access to telomere DNA
17237768 crystal structure of human TPP1 reveals an oligonucleotide/oligosaccharide-binding fold that is structurally similar to the beta-subunit of the telomere end-binding protein of a ciliated protozoan; TPP1 is the missing beta-subunit of human POT1

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDprotection of telomeres 1Homo sapiens POT1 and TIN2 organizing protein mRNA, complete cdsPTOP interacts with POT1.-Pubmed
HPRDprotection of telomeres 1adrenocortical dysplasia homolog--Pubmed
BINDTERF1-interacting nuclear factor 2Homo sapiens POT1 and TIN2 organizing protein mRNA, complete cdsPTOP interacts with TIN2.-Pubmed
HPRDTERF1-interacting nuclear factor 2adrenocortical dysplasia homolog--Pubmed
HPRDTERF1-interacting nuclear factor 2adrenocortical dysplasia homolog--Pubmed

Recent Publications on ACD:

Pubmed Logo
Expression profile of significant immortalization genes in colon cancer.
Cancer is a disease of genomic instability, a multistep process involving...
4th February, 2010
Department of Internal Medicine, Diabetology and Nephrology, Medical Int J Mol Med. 2010 Mar;25(3):321-9.
A novel, rapid method to detect infectious HIV-1 from plasma from persons infected with HIV-1.
Efficient isolation of replication competent virus from plasma of patients...
2nd February, 2010
Infectious Diseases Unit, Alfred Hospital, Melbourne, Victoria, Australia; J Virol Methods. 2010 Jan 28.
DOI Direct Link
Ethanol Modulates Corticotropin Releasing Hormone Release From the Rat Hypothalamus: Does Acetaldehyde Play a Role?
Background and Methods: Ethanol (EtOH) activates...
28th January, 2010
From the Department of Pharmacological Sciences "P. Benigno", University Alcohol Clin Exp Res. 2010 Jan 26.
DOI Direct Link
Quantitative assessment of anterior chamber parameters in pigmentary glaucoma using slit-lamp optical coherence tomography.
Purpose. To quantitatively assess the parameters of anterior chamber and...
26th January, 2010
Ophthalmology Department, Yeditepe University Eye Hospital - Turkey. Eur J Ophthalmol. 2010 Jan 13.
Evaluation of serum transferrin receptor and sTfR ferritin indices in diagnosing and differentiating iron deficiency anemia from anemia of chronic disease.
OBJECTIVE: The present study was conducted to assess the utility of serum...
22nd January, 2010
Department of Pathology, Lady Hardinge Medical College and associated Indian J Pediatr. 2010 Jan 20.
DOI Direct Link

View more research publications.

Press Releases on ACD:

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STAAR Surgical's VISIAN ICL to be Featured on CBS 'Early Show' 7th August, 2008 STAAR Surgical Company

MONROVIA, Calif., Aug. 7 /PRNewswire-FirstCall/ -- STAAR Surgical Company (Nasdaq: STAA), a leading developer, manufacturer and marketer of minimally invasive ophthalmic products, announced

BioNews Results for ACD

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Clinico-allergological pattern of allergic contact dermatitis among 70 Indian children
MDLinx:  Jan 13 2010 11:59AM Matching: acd
Nutrient mix shows potential to improve memory in Alzheimer's patients
News-Medical.Net:  Jan 7 2010 7:07AM Matching: acd
Evaluation of the Lenstar LS 900 non-contact biometer
British Journal of Ophthalmology:  Dec 22 2009 3:06AM Matching: acd
Cancer informatics for the clinician: An interaction database for chemotherapy regimens and antiepileptic drugs
MDLinx:  Dec 21 2009 9:23AM Matching: acd
Spring seminars present unique technology integration for accelerated drug discovery
Drug Discovery Online:  Dec 19 2009 9:20AM Matching: acd
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

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The Impact of Anemia of Chronic Disease on Chronic Obstructive Pulmonary Disease Patients

ACD results from Abnova

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Sponsored Results:

Abnova Logo
ACD monoclonal antibody (M01), clone 1C11-1A7
Mouse monoclonal antibody raised against a full-length recombinant ACD.
Symbol: ACD  Alias: PIP1, PTOP, TINT1, TPP1
http://www.abnova.com/products/products_detail.asp?catalog_id=H00065057-M01
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Abnova Logo
ACD 293T Cell Transient Overexpression Lysate(Denatured)

Symbol: ACD  Alias: 24432,PTOP,Pip1,TINT1
http://www.abnova.com/products/products_detail.asp?catalog_id=H00065057-T01
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Abnova Logo
ACD monoclonal antibody (M02), clone 1D8-1B6
Mouse monoclonal antibody raised against a full length recombinant ACD.
Symbol: ACD  Alias: 24432, PTOP, Pip1, TINT1
http://www.abnova.com/products/products_detail.asp?catalog_id=H00065057-M02
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Abnova Logo
ACD Recombinant Protein (P01)
ACD( AAH16904, 1 a.a. - 545 a.a.) full-length recombinant protein with GST tag.
Symbol: ACD  Alias: 24432, PTOP, Pip1, TINT1
http://www.abnova.com/products/products_detail.asp?catalog_id=H00065057-P01
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Abnova Logo
ACD Pre-design Chimera RNAi
Homo sapiens adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 1, mRNA
Symbol: ACD  Alias: 24432, PTOP, Pip1, TINT1
http://www.abnova.com/products/products_detail.asp?catalog_id=H00065057-R02
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Abnova Logo
ACD monoclonal antibody (M01A), clone 1C11-1A7
Mouse monoclonal antibody raised against a full-length recombinant ACD.
Symbol: ACD  Alias: 24432, PTOP, Pip1, TINT1
http://www.abnova.com/products/products_detail.asp?catalog_id=H00065057-M01A
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Search for ACD products at Abnova.

ACD results (if any) from reagent suppliers

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ACD Antibody / ACD Antibodies
ACD Antibody / ACD Antibodies. ... ACD specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-acd.html...

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ACD monoclonal antibody (M02)
Abgent develops powerful tools to profile posttranslational modifications related to cellular function and disease. Abgent antibodies target protein
kinases ...
http://www.abgent.com/products/catalog_no/AT1023a_ACD_monocl...

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ACD (AA-2) Antibody sc-100597
Western blot analysis of ACD expression in IMR-32 whole cell lysate. ... ACD (AA -2): sc-100597. Immunoperoxidase staining of formalin-fixed, ...
http://www.scbt.com/datasheet-100597-acd-aa-2-antibody.html...

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C3821 Citrate-dextrose solution (ACD) sterile-filtered
Useful for anticoagulation of whole blood; erythrocyte survival.
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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ACD siRNA (h) sc-93019
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: ACD ...
http://www.scbt.com/datasheet-93019-acd-sirna-h.html...

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Z407402 ACD/pKa calculator
ACD/pKa lets you draw any chemical structure with up to 50 ;atoms (including H, C, N, O, F, Cl, Br, I) and obtain predicted acid-base dissociation ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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ACD Antibody / ACD Antibodies
ACD Antibody / ACD Antibodies. ... ACD spezifische siRNA, sHRNA Plasmide und shRNA Lentivirale Partikel Gen Silencer sind ebenfalls erhältlich. ...
http://www.scbt.com/de/table-acd.html...

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