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SLC1A2
| Symbol: | SLC1A2 | | Name(s): | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | EAAT2, GLT-1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 11204345 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15296513 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16766085 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17920768 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17684493 |
The regulation of EAAT2 mRNA and protein isoforms and concludes with a summary of studies showing dysregulation of EAAT2 in psychiatric and neurological disorders. |
| 17920768 |
the -181 A/C polymorphism in the EAAT2 gene promoter affects the personality trait of reward dependence in healthy subjects |
| 12408226 |
Alzheimer disease-related neurodegeneration is associated with the expression of the glutamate transporter EAAT-2 in altered neurons. |
| 15048885 |
Despite increases in truncated splice variant EAAT2b immunostaining of astrocytes and neurons in amyotrophic lateral sclerosis motor cortex, functional transporter studies demonstrate a large loss of EAAT2 function. |
| 17311293 |
In conclusion, the idea is put forward of an epigenetic mode of EAAT2 regulation based on the differential methylation of the gene promoter. |
| 17311320 |
Transient expression of EAAT2 occurs during the window of peak vulnerability for periventricular leukomalacia, suggesting that this transporter may be a major source of extracellular glutamate in ischemic injury to the cerebral white matter. | →View more information from publications. |
Recent Publications on SLC1A2: |  |
No genetic association between the SLC1A2 gene and Japanese patients with schizophrenia.
Glutamatergic dysfunction may be a pathophysiological feature in the... | 8th August, 2009
| Juntendo University School of Medicine, Tokyo, Japan.
| Neurosci Lett. 2009 Oct 9;463(3):223-7. Epub 2009 Aug 4.
DOI Direct Link |
Select nutrients in the ovine uterine lumen. IV. Expression of neutral and acidic amino acid transporters in ovine uteri and peri-implantation conceptuses.
The availability of specific neutral and acidic amino acids in the uterine... | 31st July, 2009
| Center for Animal Biotechnology and Genomics, Department of Animal
| Biol Reprod. 2009 Jun;80(6):1196-208. Epub 2009 Jan 28.
DOI Direct Link |
Haploinsufficiency of glutamine synthetase increases susceptibility to experimental febrile seizures.
Glutamine synthetase (GS) is a pivotal glial enzyme in the... | 15th July, 2009
| Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of
| Genes Brain Behav. 2009 Apr;8(3):290-5. Epub 2008 Dec 17.
DOI Direct Link |
Expression of EAAT-1 distinguishes choroid plexus tumors from normal and reactive choroid plexus epithelium.
Microscopic distinction of normal choroid plexus (CP) from choroid plexus... | 19th June, 2009
| Institute for Brain Research, Eberhard-Karls-University, Tubingen,
| Acta Neuropathol. 2009 Jun;117(6):667-75. Epub 2009 Mar 13.
DOI Direct Link |
Association analysis between canine behavioural traits and genetic polymorphisms in the Shiba Inu breed.
The relationships between behavioural trait data and the genotype of 15... | 29th April, 2009
| Laboratory of Veterinary Ethology, The University of Tokyo, 1-1-1 Yayoi,
| Anim Genet. 2009 Oct;40(5):616-22. Epub 2009 Apr 20.
DOI Direct Link |
→View more research publications. |
SLC1A2 results (if any) from reagent suppliers | 
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SLC1A2 monoclonal antibody (M07)
SLC1A2 (NP_004162, 160 a.a. ~ 240 a.a) partial recombinant protein with GST tag. ... Detection limit for recombinant GST tagged SLC1A2 is approximately ...
http://www.abgent.com/products/catalog_no/AT3905a_SLC1A2_mon...
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EAAT2 (N-19) Antibody sc-7760
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, SLC1A2, 6506, 11p13, NM_004171 ...
http://www.scbt.com/datasheet-7760-eaat2-n-19-antibody.html...
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Abgent - Neurosciences Antibodies
AT3905aNEW, SLC1A2 monoclonal antibody (M07), ELISA,WB-Ce,WB-Re, H. AT3906aNEW, SLC1A2 monoclonal antibody (M10), ELISA,S-ELISA,WB-Re, H ...
http://www.abgent.com/products/category/neurosciences...
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EAAT Antibody / EAAT Antibodies
제품명, 카탈로그 번호, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. EAAT1 (C-19) Antibody, sc-7757, goat IgG, C-terminus (h), WB, IF, ELISA, m, r, h, dog ...
http://www.scbt.com/ko/table-eaat.html...
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