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SLC2A3


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Gene DB Home
Symbol:SLC2A3
Name(s):solute carrier family 2 (facilitated glucose transporter), member 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLJ90380, GLUT3
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17920708 IGF-1 plays a role in maintaining muscle GLUT3 expression and basal glucose uptake via the transcriptional factor Sp1.
17559076 Regulation of GLUT3 and glucose uptake by the cAMP signallling pathway in the breast cancer cell line ZR-75 is reported.
17611657 Findings suggest that characteristic differences in the patterns of glucose uptake can exist according to the histological type and that GLUT1, GLUT3 and GLUT4 could be related to tumor angiogenesis in epithelial ovarian carcinoma.
17442736 During trophoblast hypoxia glucose transporters (GLUT1/3) are upregulated via HIF-1 alpha pathway.
16125330 We present an alternative hypothesis centring on presumed deficits in membrane bound glucose transporter proteins GLUT 1 and GLUT 3, either in absolute numbers or functional capacity.
16049004 in platelets glucose transport through GLUT3 is regulated by changes in surface expression and affinity modulation, which are both under control of PKB
14757434 Differentiation of THP-1 monocytes into macrophages was associated with marked induction of GLUT 3 and GLUT 5 protein expression, and high levels of GLUT 1, GLUT 3, and GLUT 5 were maintained after transformation to foam cells.
12112827 glucose transporter 1 and 3 in the placenta
12397394 Restricted to regenerating muscle fibres and nerves in adult human muscle. GLUT3 may be important for glucose supply in fetal muscle fibres and regenerating adult muscle fibres.
16136514 This review presents a model incorporating hypoxia responsive facilitative GLUT1 and GLUT3 as putative components of the glucose sensing apparatus in chondrocytes

View more information from publications.

Recent Publications on SLC2A3:

Pubmed Logo
First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children.
Dyslexia is one of the most common learning disorders affecting about 5%...
30th September, 2009
Max-Planck Institute of Psychiatry, Munich, Germany. Mol Psychiatry. 2009 Sep 29.
DOI Direct Link
Essential role of glucose transporter GLUT3 for post-implantation embryonic development.
Deletion of glucose transporter gene Slc2a3 (GLUT3) has previously been...
31st July, 2009
Department of Pharmacology Toxicology, German Institute of Human J Endocrinol. 2009 Jan;200(1):23-33. Epub 2008 Oct 23.
DOI Direct Link
Type-2 diabetes down-regulates glucose transporter proteins and genes of the human blood leukocytes.
OBJECTIVE: White blood cells are essential in mediating immune and...
8th July, 2009
Department of Biochemistry, Akdeniz University, Medical Faculty, Antalya, Scand J Clin Lab Invest. 2009;69(3):350-8.
DOI Direct Link
Studies of insulin resistance in patients with clinical and subclinical hypothyroidism.
OBJECTIVE: Although clinical hypothyroidism (HO) is associated with...
19th May, 2009
Hellenic National Center for Research, Prevention and Treatment of Eur J Endocrinol. 2009 May;160(5):785-90. Epub 2009 Jan 13.
DOI Direct Link
Vitamin C enters mouse T cells as dehydroascorbic acid in vitro and does not recapitulate in vivo vitamin C effects.
Vitamin C is an essential micronutrient, which has been implicated in...
8th May, 2009
Department of Anatomy and Tumor Immunity Medical Research Center, Seoul Immunobiology. 2009;214(4):311-20. Epub 2008 Oct 23.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
7171311 Methods of assigning treatment to breast cancer patients
7183057 Tape stripping methods for analysis of skin disease and pathological skin state
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

View more patents.

SLC2A3 results (if any) from reagent suppliers

Google CSE Logo
Glut3 (G-5) Antibody sc-74399
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, SLC2A3, 6515, 12p13.31, NM_006931 ...
http://www.scbt.com/datasheet-74399-glut3-g-5-antibody.html...

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Glut3 (I-14) Antibody sc-31838
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Mouse, Slc2a3, 20527, 6 F2, P32037 ...
http://www.scbt.com/datasheet-31838-glut3-i-14-antibody.html...

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