Monday November 23 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

BMP5


Suggest Content
Advertise Here
Gene DB Home
Symbol:BMP5
Name(s):bone morphogenetic protein 5
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC34244
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15861517 To analyze the expression of bone morphogenetic proteins (BMPs) in prostate and breast cancers with established metastasis in bone
15516325 BMP-5 increases the levels of osteopontin, BMP-2, alkaline phosphatase and core binding factor alpha 1 mRNAs in human periodontal (HPL) ligament cells.
16542506 BMP5 is expressed in normal synovial tissue and was decreased in osteoarthritis and rheumatoid arthritis.
11642720 The expression signals of BMP-5 mRNA in malignant schwannoma were relatively lower than in benign lesions
17220169 The differential allelic expression (DAE) of BMP5 in human mesenchymal tissues obtained from 16 donors undergoing joint replacement for treatment of osteoarthritis, was examined.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDBone morphogenetic protein 5noggin precursor--Pubmed
HPRDBone morphogenetic protein 5follistatin isoform FST344 precursor--Pubmed
HPRDbone morphogenetic protein 5 preproproteinFollistatin--Pubmed
HPRDbone morphogenetic protein 5 preproproteinNoggin--Pubmed

Recent Publications on BMP5:

Pubmed Logo
BMPs and Chordin regulate patterning of the directive axis in a sea anemone.
The TGF-beta molecules Dpp/BMP2/4/7 and their antagonist Sog/Chd play a...
17th October, 2009
Sars International Centre for Marine Molecular Biology, University of Proc Natl Acad Sci U S A. 2009 Oct 15.
DOI Direct Link
Bone morphogenetic proteins 2 and 5 are down-regulated in adrenocortical carcinoma and modulate adrenal cell proliferation and steroidogenesis.
Bone morphogenetic proteins (BMP) have been shown to affect tumorigenesis...
26th September, 2009
Departments of Medicine, University Hospital Innenstadt, Ludwig Cancer Res. 2009 Jul 15;69(14):5784-92. Epub 2009 Jul 7.
DOI Direct Link
Shaping skeletal growth by modular regulatory elements in the Bmp5 gene.
Cartilage and bone are formed into a remarkable range of shapes and sizes...
4th April, 2009
Department of Developmental Biology, Stanford University School of PLoS Genet. 2008 Dec;4(12):e1000308. Epub 2008 Dec 19.
DOI Direct Link
Bone morphogenic factor gene dosage abnormalities in prostatic intraepithelial neoplasia and prostate cancer.
Abnormal expression of bone morphogenic proteins (BMP) has been reported...
25th June, 2008
School of Medicine, University of Wales Swansea, Singleton Park, Swansea Cancer Genet Cytogenet. 2007 Jul 15;176(2):161-5.
DOI Direct Link
Dominant negative Bmp5 mutation reveals key role of BMPs in skeletal response to mechanical stimulation.
BACKGROUND: Over a hundred years ago, Wolff originally observed that bone...
6th May, 2008
Department of Developmental Biology and Howard Hughes Medical Institute, BMC Dev Biol. 2008 Apr 1;8:35.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
6972321 Monomeric protein of the TGF-.beta. family
7148036 DNA molecules encoding cartilage-derived morphogenetic proteins
7153684 Pluripotential embryonic stem cells and methods of making same
7160698 Fluorescent and colored proteins, and polynucleotides that encode these proteins
7186689 Mutants of bone morphogenetic proteins

View more patents.

BMP5 results (if any) from reagent suppliers

Google CSE Logo
BMP5 Antibody BMP5
BMP5 antibody was raised against a synthetic peptide of BMP5.,
http://www.prosci-inc.com/shop/catalog1/BMP5-Antibody-p-2771...

Thumbshot
BMP-5 (N-19) Antibody sc-7405
See how others have used BMP-5 (N-19): sc-7405 antibody and or BMP-5 (N-19) ... A new role for BMP5 during limb development acting through the synergic ...
http://www.scbt.com/datasheet-7405-bmp-5-n-19-antibody.html...

Thumbshot
Human BMP-5 Biotinylated Mab (Clone 78201)
and read the corresponding human BMP-5 concentration. If samples have been diluted, the concentration read from the standard curve must ...
http://www.rndsystems.com/pdf/bam7152.pdf...

Thumbshot
BMP5 antibodies: Stem Cells > Signaling Pathways > TGF beta ...
BMP5 antibodies. ... Image Abreview Publication. ab10858 · BMP5 antibody. IHC-P, WB, Inhib, ELISA, IHC-Fr. Goat polyclonal ...
http://www.abcam.com/index.html?t=8590&pt=1&c=3516&ei=&mu=ra...

Thumbshot
Anti-Bone Morphogenetic Protein 5 antibody produced in goat (B3805 ...
are incubated with the primary antibody (anti-BMP-5) at concentrations of at least 5 to 10 µg/ml. ... floating sections, anti-BMP-5 should be diluted to at
...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...

Thumbshot
Bone morphogenetic protein 5 (BMP5) polyclonal antibody - Orbigen ...
KLH conjugated synthetic peptide comprised of amino acids 31 - 46 [ DNHVHSSFIYRRLRNH] of the human bone morphogenetic protein 5 (BMP5) protein. ...
http://www.orbigen.com/commerce/catalog/product.jsp?product_...

Thumbshot
BMP-5 - R&D Systems
BMP-5. BMPs are secreted signaling molecules that comprise a subfamily of the TGF-beta superfamily and were originally identified as regulators of cartilage
...
http://www.rndsystems.com/molecule_detail.aspx?m=1115...

Thumbshot

Search Bioportfolio and other Life Science Sites for BMP5, or search for BMP5 on BioPortfolio's antibody search engine.
This page has been viewed 407 times
Recent Search Terms used to find this page:
Bone Morphogenic medical coding | shwanoma BMP | BMP5 | bmp5 expression osteoarthritis | bmp5 | Cancer Genet Cytogenet. 2007 Jul 15 176 2 161-5 | HPL-H44 | BMP5 | Bmp5 and prostate cancer | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.