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BMPR1B
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15235019 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 16436528 |
Human granulosa-like tumor cell line KGN expressed BMP type I (BMPR1A and BMPR1B) and type II receptors (BMPR2) and the BMP signaling molecules SMADs (SMAD1 and SMAD5). |
| 14576167 |
BMP-2-induced apoptosis was mediated by BMP-RIB in osteoblasts and occurred independently of BMP-2-induced osteoblast differentiation. |
| 17363346 |
significant shift in the emission maximum from 498 to 510 nm was detected when bis-ANS binds ecBMPR-IB. FRET revealed close proximity between the tyrosine & bis-ANS binding site. |
| 14523231 |
performed linkage analysis in brachydactyly (BD) type A2 and mapped a locus for BD type A2 to 4q21-q25. This interval includes the gene bone morphogenetic protein receptor 1B. |
| 15192043 |
the BMP system is strongly involved in pulmonary artery smooth muscle mitosis through ALK-6, resulting in the progression of vascular remodeling of pulmonary arteries in pulmonary hypertension. |
| 16014698 |
GDF5 is a novel brachydactyly type A2 causing gene involving BMPR1b impaired activity. |
| 17001689 |
Results indicate that increased bone morphogenetic protein receptor (BMPR)-IB by TGF-beta1, FGF-2, and PDGF-AB significantly enhances BMP-2-induced osteogenesis in vitro. |
| 17381068 |
Our results indicated the potential involvement of ALK6 activation by rhTGFbetas in the synergy between rhTGFbetas and rhBMPs. |
| 15897891 |
Anti mullerian hormnoe is a gonadal tumor suppressor which mediates its effects through a specific type II receptor and the bone morphogenetic protein (BMP)-specific Smad proteins. | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Bone morphogenetic protein 2 | bone morphogenetic protein receptor, type IB precursor | - | - | Pubmed |
| HPRD | bone morphogenetic protein 2 preproprotein | Bone morphogenetic protein receptor, type IB | - | - | Pubmed |
| HPRD | Bone morphogenetic protein 4 | bone morphogenetic protein receptor, type IB precursor | - | - | Pubmed |
| HPRD | bone morphogenetic protein 4 preproprotein | Bone morphogenetic protein receptor, type IB | - | - | Pubmed |
| BIND | bone morphogenetic protein 4 preproprotein | bone morphogenetic protein receptor, type IB precursor | BMP4 interacts with BMPR1B (BR). This interaction was modeled on a demonstrated interaction between BMP4 from an unspecified species and BMPR1B from an unspecified species. | - | Pubmed |
| HPRD | Bone morphogenetic protein 6 | bone morphogenetic protein receptor, type IB precursor | - | - | Pubmed |
| HPRD | bone morphogenetic protein 6 preproprotein | Bone morphogenetic protein receptor, type IB | - | - | Pubmed |
| HPRD | Bone morphogenetic protein 7 | bone morphogenetic protein receptor, type IB precursor | - | - | Pubmed |
| HPRD | bone morphogenetic protein 7 precursor | Bone morphogenetic protein receptor, type IB | - | - | Pubmed |
| HPRD | BMP receptor, type IA | bone morphogenetic protein receptor, type IB precursor | - | - | Pubmed |
Recent Publications on BMPR1B: |  |
Six2 activity is required for the formation of the mammalian pyloric sphincter.
The functional activity of Six2, a member of the so/Six family of... | 3rd November, 2009
| Department of Genetics and Tumor Cell Biology, MS 331, St. Jude Children's
| Dev Biol. 2009 Oct 15;334(2):409-17. Epub 2009 Aug 3.
DOI Direct Link |
4q32-q35 and 6q16-q22 are valuable candidate regions for split hand/foot malformation.
On the basis of the Human Cytogenetic Database, a computerized catalog of... | 9th October, 2009
| Institute of Medical Genetics, University of Zurich, Schwerzenbach,
| Eur J Hum Genet. 2009 Aug;17(8):1086-91. Epub 2009 Feb 18.
DOI Direct Link |
A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis.
MicroRNAs regulate diverse cellular processes and play an integral role in... | 8th October, 2009
| Department of Cancer Research and Molecular Medicine, Norwegian University
| Cancer Res. 2009 Sep 15;69(18):7459-65. Epub 2009 Sep 8.
DOI Direct Link |
BMP and BMP receptor expression during murine organogenesis.
Cell-cell communication is critical for regulating embryonic organ growth... | 3rd October, 2009
| Department of Molecular Biology, NA8.300, University of Texas Southwestern
| Gene Expr Patterns. 2009 Jun;9(5):255-65. Epub 2009 Apr 22.
DOI Direct Link |
Evidence against involvement of Bmp receptor 1b signaling in fate specification of the chick mesencephalic alar plate at HH16.
Studies in the developing spinal cord have established that morphogenes... | 24th September, 2009
| Max Planck Institute for Brain Research, Deutschordenstr. 46, 60528
| Neurosci Lett. 2009 Sep 25;461(3):223-8. Epub 2009 Jun 16.
DOI Direct Link |
→View more research publications. |
BMPR1B results (if any) from reagent suppliers | 
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BMPR1B antibodies: Stem Cells > Mesenchymal Stem Cells > Surface ...
BMPR1B antibodies. ... BMPR1B antibody [MM0055-3E12]. IHC-P, WB. Images. Mouse monoclonal. Reacts with: Hu. Terms and conditions · Legal · Privacy policy ...
http://www.abcam.com/index.html?t=47981&pt=1&c=3547&ei=&mu=r...
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Transforming Growth Factor beta (TGF-beta)
B0937, Anti-BMPR1B (151-165) antibody produced in rabbit, (polyclonal), IgG fraction of antiserum, human ... BMPR1B(658) ...
https://www.sigmaaldrich.com/etc/controller/controller-page....
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Abgent - Stem Cell
AP2004f, BMPR1A Antibody (N-term), WB, E, H. AP2005b, BMPR1B Antibody (C-term), WB, IHC, E, H. AP2005a, BMPR1B Antibody (N-term K15), WB, E, H, M ...
http://www.abgent.com/products/category/stem_cell...
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TGFβ RI (T-19) Antibody sc-402
Human, BMPR1B, 658, 4q22.3, NM_001130916, NM_004612 · O00238 · 603248. Human, TGFBR1, 7046, 9q22.33, NM_004612 · P36897 ...
http://www.scbt.com/datasheet-402-tgfbeta-ri-t-19-antibody.h...
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BMPR2 antibody (ab10862) | Abcam
The bone morphogenetic protein (BMP) receptors belong to a family of transmembrane serine/threonine kinases including the type I receptors BMPR1A and
BMPR1B ...
http://www.abcam.com/BMPR2-antibody-ab10862.html...
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BMPR-IB (H-44) Antibody sc-25455
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, BMPR1B, 658, 4q22.3, NM_001203 ...
http://www.scbt.com/datasheet-25455-bmpr-ib-h-44-antibody.ht...
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BMPR1A antibody (ab10861) | Abcam
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B ...
http://www.abcam.com/BMPR1A-antibody-ab10861.html...
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