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BMPR2
| Symbol: | BMPR2 | | Name(s): | bone morphogenetic protein receptor, type II (serine/threonine kinase) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | BMPR-II, BMPR3, BMR2, BRK-3, FLJ76945, PPH1, T-ALK, TRG10 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18356561 |
Observational study of gene-disease association. (HuGE Navigator) |
| 12358323 |
Observational study of gene-environment interaction. (HuGE Navigator) |
| 12415595 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15235019 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 15358693 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15965979 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 16717148 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18187665 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17700526 |
Conditional inactivation of BMP type II receptor (BMPRII) in the stroma leads to epithelial hyperplasia throughout the colon with increased epithelial cell proliferation. |
| 18159113 |
ALK1 plays as notable a role as BMPR2 in the etiology of PAH. Asymptomatic carriers with the ALK1 mutation within the serine - threonine kinase domain are at risk of developing PAH and hereditary hemorrhagic telangiectasia | →View more information from publications. |
Recent Publications on BMPR2: |  |
Novel Loci Interacting Epistatically With Bone Morphogenetic Protein Receptor 2 Cause Familial Pulmonary Arterial Hypertension.
BACKGROUND: Familial pulmonary arterial hypertension (FPAH) is a rare,... | 30th October, 2009
| Division of Statistical Genetics, Department of Biostatistics, Columbia
| J Heart Lung Transplant. 2009 Oct 26.
DOI Direct Link |
The angiopietin-1-Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice.
The role of the angiopoietin-1 (Ang1)-Tie2 pathway in the pathogenesis of... | 23rd October, 2009
| Laboratory Medicine and Pathobiology, University of Toronto, Toronto,
| J Exp Med. 2009 Sep 28;206(10):2221-34. Epub 2009 Sep 8.
DOI Direct Link |
S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4.
RATIONALE: S100A4/Mts1 is implicated in motility of human pulmonary artery... | 16th October, 2009
| Department of Pediatrics, Stanford University School of Medicine,
| Circ Res. 2009 Sep 25;105(7):639-47, 13 p following 647. Epub 2009 Aug 27.
DOI Direct Link |
Genetics of pulmonary arterial hypertension.
Tremendous progress has been made in understanding the genetics of... | 13th October, 2009
| Department of Pediatrics, Division of Pulmonary, Allergy, and Immunology
| Semin Respir Crit Care Med. 2009 Aug;30(4):386-98. Epub 2009 Jul 24.
DOI Direct Link |
[Bone morphogenetic protein type II receptor gene promoter mutation-142G > A in a patient with familial pulmonary arterial hypertension]
OBJECTIVE: To investigate the relation between bone morphogenetic protein... | 7th October, 2009
| Department of Respiratory Medicine, Chinese PLA General Hospital, Beijing
| Zhonghua Yi Xue Za Zhi. 2009 Feb 3;89(4):230-4.
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→View more research publications. |
BMPR2 results (if any) from reagent suppliers | 
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BMPR2 antibody (ab10862) | Abcam
Goat polyclonal to BMPR2. The bone morphogenetic protein (BMP) receptors belong to a family of transmembrane serine/threonine kinases including the type I ...
http://www.abcam.com/BMPR2-antibody-ab10862.html...
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BMPR2 Antibody (N-term)
BMPR2 Antibody (N-term) Cell Function, BMPR2 Antibody (N-term) Protein Modification, BMPR2 Antibody (N-term) Stem Cell, BMPR2 Antibody (N-term) Cell
...
http://www.abgent.com/products/catalog_no/AP2006a...
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BMPR2 antibody [MM0060-9A10] (ab78422) | Abcam
Mouse monoclonal [MM0060-9A10] to BMPR2. The bone morphogenetic protein (BMP) receptors belong to a family of transmembrane serine/threonine kinases ...
http://www.abcam.com/BMPR2-antibody-MM0060-9A10-ab78422.html...
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Orbigen Inc. - Orbigen Inc.
KLH conjugated synthetic peptide comprised of amino acids 34 - 49 [ CAFKDPYQQDLGIGES] of the human bone morphogenetic protein receptor type II (
BMPR2) ...
http://www.orbigen.com/commerce/catalog/product.jsp?product_...
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BMPR2 antibodies: Signal Transduction > Cytoskeleton / ECM ...
BMPR2 antibodies. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab10862 · BMPR2 antibody. WB, ELISA. Goat polyclonal ...
http://www.abcam.com/index.html?t=47987&pt=1&c=2246&ei=&mu=r...
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Transforming Growth Factor beta (TGF-beta)
B1187, Anti-BMPR2 (631-645) antibody produced in rabbit, (polyclonal), IgG fraction of antiserum, human ... BMPR2(659) ...
https://www.sigmaaldrich.com/etc/controller/controller-page....
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BMPR-II (T-18) Antibody sc-5683
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, BMPR2, 659, 2q33.1, NM_001204 ...
http://www.scbt.com/datasheet-5683-bmpr-ii-t-18-antibody.htm...
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