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SMARCA2
| Symbol: | SMARCA2 | | Name(s): | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | BAF190, BRM, FLJ36757, MGC74511, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16749937 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17938176 |
p53 activity is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes |
| 18082132 |
C/EBPbeta and GATAs may developmentally regulate the expression of brm by mutually exclusive binding. |
| 18006815 |
Brm is required for villin expression, a definitive marker of intestinal metaplasia and differentiation |
| 17546055 |
Loss of BRM through epigenetic silencing is associated with neoplasms |
| 11850427 |
Brm-containing SWI/SNF complex subfamily (trithorax-G) and a complex including YY1 and HDACs (Polycomb-G) counteract each other to maintain transcription of exogenously introduced genes |
| 14657023 |
Cell culture in the presence of HDAC inhibitors facilitates the isolation of clones overexpressing Brm. |
| 12566296 |
This report provides supportive evidence that BRG1 and BRM act as tumor suppressor proteins and implicates a role for their loss in the development of non-small cell lung cancers. |
| 15240517 |
BRM and BRG1 participate in two distinct chromosome remodeling complexes that are functionally complementary in non-small cell lung cancer |
| 11719516 |
Brm could also drive expression of CD44; Brm can compensate for BRG-1 loss as pertains to RB sensitivity | →View more information from publications. |
Recent Publications on SMARCA2: |  |
Involvement of the chromatin-remodeling factor BRG1/SMARCA4 in human cancer.
The SWI/SNF complex is a chromatin-remodeling complex that uses the energy... | 17th July, 2008
| Department of Molecular, Cellular and Developmental Biology, Yale
| Epigenetics. 2008 Mar-Apr;3(2):64-8. Epub 2008 Apr 17.
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ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation.
The immunodeficiency, centromeric region instability, and facial anomalies... | 5th June, 2008
| Hayward Human Genetics Program, Tulane Medical School, New Orleans, LA
| Autoimmunity. 2008 May;41(4):253-71.
DOI Direct Link |
Regulation of apoptotic and growth inhibitory activities of C/EBPalpha in different cell lines.
C/EBPalpha is expressed in many tissues and inhibits cell growth. In this... | 24th May, 2008
| Department of Pathology, Baylor College of Medicine, One Baylor Plaza,
| Exp Cell Res. 2008 Apr 15;314(7):1626-39. Epub 2008 Feb 13.
DOI Direct Link |
Brm transactivates the telomerase reverse transcriptase (TERT) gene and modulates the splicing patterns of its transcripts in concert with p54(nrb).
We report that a DBHS (Drosophila behaviour, human splicing) family... | 16th April, 2008
| Division of Host-Parasite Interaction, Department of Microbiology and
| Biochem J. 2008 Apr 1;411(1):201-9.
DOI Direct Link |
The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development.
ATP-dependent chromatin-remodeling complexes contribute to the proper... | 9th April, 2008
| Department of Genetics, University of North Carolina at Chapel Hill,
| Development. 2008 Feb;135(3):493-500. Epub 2007 Dec 19.
DOI Direct Link |
→View more research publications. |
SMARCA2 results (if any) from reagent suppliers | 
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SMARCA2 antibody (ab42551) datasheet | Abcam
Rabbit polyclonal to SMARCA2 / BRM. A transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation.
http://www.abcam.com/?datasheet=42551...
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SMARCA2/BRM Antibody Bethyl Laboratories
Rabbit anti-SMARCA2/BRM Antibody, Affinity Purified.
http://www.bethyl.com/go/?product/A301-015A...
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SMARCA2 SWI/SNF related, matrix associated, actin dependent ...
SMARCA2; BAF190; BRM; FLJ36757; HBRM; HSNF2A; MGC74511; SNF2; SNF2L2; SNF2LA; STH1P; SWI2. Other Designations. SNF2-alpha; SNF2-like 2; SNF2/SWI2-like ...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...
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NatuTec - Antibodies Cell Surface, FoxP3, Trueblot, Cell ...
SMARCA2/BRM Antibody AbVantage(TM) Pack, 1 pack, A310-327A. Informationen anfordern. SNF2h/ISWI Antibody AbVantage(TM) Pack, 1 pack, A310-328A ...
http://www.natutec.de/search.php?level1=&level2=&level3=&que...
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GRAA2 Panorama Antibody Microarray Gene Regulation I Kit
... PRMT1(3276), PRMT3(10196), PRMT5(10419), PRMT6(55170), PTX3(5806), RAN(5901), SMARCA2(6595), SMARCA4(6597), SMARCB1(6598), SP1(6667), SUV39H1(6839), ...
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...
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H9662 Anti hBRM hSNF2a LG 14 antibody produced in rabbit IgG ...
application(s). immunoblotting: 1:1000 using extracts of 293T cells transfected with hBRM. Gene Information. human ... SMARCA2(6595). shipped in ...
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...
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XP725 Panorama Antibody Microarray XPRESS Profiler725 Kit
... SMAD4(4089), SMARCA2(6595), SMARCA4(6597), SMARCB1(6598), SMARCE1(6605), SMC1A(8243), SMN1(6606), SMN2(6607), SNAP23(8773), SNAP25(6616), SNCA(6622), ...
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...
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Antibodies to Transcription Regulators
SMARCA2(6595), human, ARR, IF (i), WB. H9662, Anti-hBRM/hSNF2α (LG-14) antibody produced in rabbit, IgG fraction of antiserum, human ... SMARCA2(6595) ...
http://www.sigmaaldrich.com/catalog/search/TablePage/1383597...
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Search Bioportfolio and other Life Science Sites for SMARCA2
Recent Search Terms used to find this page: 6595 | Involvement of the chromatin-remodeling factor BRG1 SMARCA4 in human cancer | SWI SNF-related matrix-associated actin-dependent regulator of chromatin a2 isoform a | Involvement of the chromatin-remodeling factor BRG1 SMARCA4 in human cancer | purified chromatin suppliers | swi snf chip | HDAC1 antibody ChIP | mouse brm variant 3 | smarca2 gene | .
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