Wednesday November 25 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

BMX


Suggest Content
Advertise Here
Gene DB Home
Symbol:BMX
Name(s):BMX non-receptor tyrosine kinase
Type:protein-coding
Organism:Homo sapiens
Synonyms:ETK, PSCTK2, PSCTK3
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18196928 Etk/Bmx may have different biological roles in tumor and nontumor cells, and may be involved in regulating hepatocyte differentiation by c-Fos activation in HCC.
17823122 results demonstrate that Bmx is a critical downstream target of the constitutively active PI 3-kinase in PTEN-deficient PCa cells and further show that Bmx is recruited by the EGF receptor and ErbB3 and activated in response to their respective ligands
16912182 Etk transgenic mouse model may be a useful tool for studying the functions of Etk and identification of new molecular markers and drug targets relevant to human diseases.
14981536 Pim1 and Etk are required for IL6-induced activation of androgen receptor-mediated transcription in prostate cancer.
14676838 Etk activation is essential for transducing the EGF-induced apoptotic signaling in breast cancer cells.
12370298 BMX/Etk is a TNFR2-specific kinase involved in TNF-induced angiogenic events
16932810 Role of Bmx in ischemia-mediated arteriogenesis/angiogenesis: response to ischemia, enhanced in transgenic mice.
16186805 two isoforms of Pim-1 kinase may regulate distinct substrates and the 44 kDa Pim-1 may play a more prominent role in drug resistance in prostate cancer cells and interact directly with tyrosine kinase Etk/BMX
15207703 Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDBone marrow kinase BMXHomo sapiens p21 activated kinase 1B mRNA, complete cds.--Pubmed
HPRDBone marrow kinase BMXcaveolin 1--Pubmed
HPRDBone marrow kinase BMXcaspase 3 preproprotein--Pubmed
HPRDBone marrow kinase BMXproto-oncogene tyrosine-protein kinase SRC--Pubmed
HPRDBone marrow kinase BMXPTK2 protein tyrosine kinase 2 isoform b--Pubmed
HPRDBone marrow kinase BMXsignal transducer and activator of transcription 3 isoform 1--Pubmed
HPRDBMX non-receptor tyrosine kinasec-Src--Pubmed
HPRDBMX non-receptor tyrosine kinaseSTAT3--Pubmed
HPRDBMX non-receptor tyrosine kinaseCaspase 3--Pubmed
HPRDBMX non-receptor tyrosine kinaseFAK--Pubmed

Recent Publications on BMX:

Pubmed Logo
The role of Tec family kinases in mononuclear phagocytes.
Mononuclear phagocytes, including monocytcs, macrophages, and dendritic...
30th September, 2009
Institute of Immunology, Center for Physiology, Pathophysiology and Crit Rev Immunol. 2009;29(4):317-33.
Subclavian artery and jugular vein rupture after a blunt thoracic trauma due to a BMX handlebar.
BACKGROUND: Copy-number variations (CNVs) are structural variations in the...
25th August, 2009
Plastic, Hand and Reconstructive Surgery, Hannover Medical School, Eur J Cardiothorac Surg. 2009 Aug 21.
DOI Direct Link
Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk.
The Tec (tyrosine kinase expressed in hepatocellular carcinoma) family of...
17th April, 2009
National Human Genome Research Institute, National Institutes of Health, Immunol Rev. 2009 Mar;228(1):93-114.
DOI Direct Link
Phylogeny of Tec family kinases identification of a premetazoan origin of Btk, Bmx, Itk, Tec, Txk, and the Btk regulator SH3BP5.
It is generally considered mammals and birds have five Tec family kinases...
27th February, 2009
Institute of Medical Technology, FI-33014 University of Tampere, Finland. Adv Genet. 2008;64:51-80.
DOI Direct Link
Effects of sodium bicarbonate ingestion on performance and perceptual responses in a laboratory-simulated BMX cycling qualification series.
The objective of this study was to examine the effect of sodium...
12th February, 2009
Department of Physical Education and Sport, University of Granada, J Strength Cond Res. 2008 Sep;22(5):1645-53.
DOI Direct Link

View more research publications.

Press Releases on BMX:

BioPortfolio Logo
Tony Hawk and Live Like a Champion Tour Roll Into Magnolia Science Academy to Promote Active Lifestyles 13th November, 2009 Activision Publishing, Inc.
-- Closing Ceremony: Children engage in post-activity stretch exercises and join in an award ceremony, declaring all who participated champions

Tony Hawk:

Largest Organ and Tissue Donation Event in U.S. to Cap April's National Donate Life Month Observances 8th April, 2009 OneLegacy

More than 7,000 Southlanders, Chikezie, Kris Jenner and Khloe Kardashian to Walk in Seventh Annual Donate Life Run/Walk, April 25, Cal State Fullerton

More Than 100

Five U.S. Children Selected to Participate in First-Ever McDonald's Champion Kids(TM) Program 25th July, 2008 McDonald's

OAK BROOK, Ill., July 25 /PRNewswire/ -- Today, at the Junior Olympic Skills Competition in Chicago, McDonald's along with U.S. Olympic wrestler Patricia Miranda announced the selection of

BioNews Results for BMX

: RSS Logo
BioPortfolio Logo
Court: Burglars headed to prison
Individual.com:  Oct 29 2009 5:34PM Matching: bmx
Leatt brings new brand identity on its sports product line
News-Medical.Net:  Oct 24 2009 8:14AM Matching: bmx
Leatt Introduces New Brand Identity
Yahoo! Canada:  Oct 23 2009 6:32PM Matching: bmx
Cancer doesnt stop John Holleman
Siskiyou Daily News:  Oct 21 2009 5:50PM Matching: bmx

Clinical Trials:

Clinical Trials Logo
Study of Surgical Mesh for Inguinal Hernia Repair

Patents:

Patents logo
US Patent No.Title
7354762 Method for producing CE7-specific redirected immune cells
7449582 Compounds and compositions as protein kinase inhibitors
7452887 Quinoline- and isoquinoline-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
7459308 Nucleic acid molecule encoding a CLASP-2 transmembrane protein
7465726 Substituted pyrrolo[2.3-B]pyridines

View more patents.

BMX results (if any) from reagent suppliers

Google CSE Logo
Bmx (N-16) Antibody sc-8873
See how others have used Bmx (N-16): sc-8873 antibody and or Bmx (N-16) ... Western blot analysis of Bmx expression in non-transfected: sc-117752 (A) and
...
http://www.scbt.com/datasheet-8873-bmx-n-16-antibody.html...

Thumbshot
HPA001048 Anti-BMX antibody produced in rabbit Prestige Antibodies ...
HPA001048 Anti-BMX antibody produced in rabbit Prestige Antibodies Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=HPA0...

Thumbshot
Bmx (C-17) Antibody sc-8874
See how others have used Bmx (C-17): sc-8874 antibody and or Bmx (C-17) antibody ... Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and ...
http://www.scbt.com/datasheet-8874-bmx-c-17-antibody.html...

Thumbshot
BMX antibodies: Signal Transduction > Protein Phosphorylation ...
BMX antibodies. ... BMX antibody. WB. Rabbit polyclonal. Reacts with: Hu, Ms, Rb . ab32153 · BMX antibody [Y396]. IP, WB. Images. Rabbit monoclonal ...
http://www.abcam.com/index.html?t=124713&pt=1&c=2119&ei=&mu=...

Thumbshot
Bmx (H-220) Antibody sc-20711
Bmx shRNA (h) Lentiviral Particles, sc-38941-V, 200 µl ... Bmx (H-220): sc-20711 . Western blot analysis of Bmx expression in non-transfected: sc-117752 (A) ...
http://www.scbt.com/datasheet-20711-bmx-h-220-antibody.html...

Thumbshot
BMX protein (Active) (ab60877) | Abcam
BMX protein (Active). Tyrosine kinases are either receptor molecules, which contain transmembrane and extracellular domains, or nonreceptor proteins, ...
http://www.abcam.com/BMX-protein-Active-ab60877.html...

Thumbshot
Bmx Antibody / Bmx Antibodies
Bmx Antibody / Bmx Antibodies. ... Bmx specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-bmx.html...

Thumbshot

Search Bioportfolio and other Life Science Sites for BMX, or search for BMX on BioPortfolio's antibody search engine.
This page has been viewed 547 times
Recent Search Terms used to find this page:
txk, a member of tec tyrosine kinase | BMX kinase | Cytoplasmic tyrosine-protein kinase BMX cell types | BMX bone | bmx roles | non-receptor tyrosine kinase | interaction receptor tyrosine kinase vs non-receptor tyrosine kinase | function of BMX kinase | txk, member of tec tyrosine kinase | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.