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SNCG


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Symbol:SNCG
Name(s):synuclein, gamma (breast cancer-specific protein 1)
Type:protein-coding
Organism:Homo sapiens
Synonyms:BCSG1, SR
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11585599 Observational study of gene-disease association. (HuGE Navigator)
14556204 Observational study of gene-disease association. (HuGE Navigator)
17373700 Observational study of gene-disease association. (HuGE Navigator)
17681534 A comparison of the structural and dynamic properties of the free states of all three synucleins, is reported in order to shed light on differences that may help to explain their different propensities to aggregate.
17534899 SNCG is a new unfavorable prognostic marker for breast cancer progression and a potential target for breast cancer treatment.
17369845 tobacco exposure induces the abnormal expression of SNCG in lung cancer cells through downregulation of DNMT3B
16821081 This study suggests that the expression of SNCG is an independent predictive marker for recurrence and metastasis in breast cancer progression.
16596223 Inducing demethylation of SNCG by hepatocarcinogens may represent one underlying mechanism for the aberrant expression of SNCG in hepatoma.
15596044 Up-regulation of gamma-synuclein is associated with bladder cancer
12121974 role in promoting cancer cell survival and inhibition of stress- and chemotherapy drug-induced apoptosis by modulating MAPK pathways

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDMitotic checkpoint kinase MAD3Lsynuclein, gamma--Pubmed
HPRDBUB1 budding uninhibited by benzimidazoles 1 homolog betasynuclein, gamma--Pubmed
HPRDG protein coupled receptor kinase 5synuclein, gamma--Pubmed
HPRDG protein-coupled receptor kinase 5Synuclein, gamma--Pubmed
HPRDmitogen-activated protein kinase 8 isoform JNK1 alpha2synuclein, gamma--Pubmed
HPRDmitogen-activated protein kinase 8 isoform JNK1 alpha2synuclein, gamma--Pubmed

Recent Publications on SNCG:

Pubmed Logo
[Identification of antigenic epitope regions recognized by anti-synuclein-gamma monoclonal antibodies]
OBJECTIVE: To identify the antigenic epitope regions recognized by...
4th September, 2009
Key laboratory of Carcinogenesis and Translational Research, Department of Beijing Da Xue Xue Bao. 2009 Jun 18;41(3):361-7.
Tumor cell-microenvironment interaction models coupled with clinical validation reveal CCL2 and SNCG as two predictors of colorectal cancer hepatic metastasis.
PURPOSE: This study aimed to identify novel biological markers for the...
27th August, 2009
State Key Laboratory of Molecular Oncology, Cancer Institute (Hospital), Clin Cancer Res. 2009 Sep 1;15(17):5485-93. Epub 2009 Aug 25.
DOI Direct Link
Porcine gamma-synuclein: molecular cloning, expression analysis, chromosomal localization and functional expression.
The gamma-synuclein protein is involved in breast carcinogenesis and has...
25th July, 2009
Department of Genetics and Biotechnology, Faculty of Agricultural Mol Biol Rep. 2009 May;36(5):971-9. Epub 2008 May 7.
DOI Direct Link
Synuclein-gamma (SNCG) may be a novel prognostic biomarker in uterine papillary serous carcinoma.
OBJECTIVES: SNCG in breast cancer is a marker for advanced and aggressive...
8th July, 2009
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Gynecol Oncol. 2009 Aug;114(2):293-8. Epub 2009 May 24.
DOI Direct Link
Endogenous growth hormone in human retinal ganglion cells correlates with cell survival.
PURPOSE: Locally synthesized growth hormone (GH) may act as a survival...
10th June, 2009
Department of Physiology, University of Alberta, Edmonton, Alberta, Mol Vis. 2009;15:920-6. Epub 2009 May 4.

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
6610484 Identifying material from a breast duct

SNCG results (if any) from reagent suppliers

Google CSE Logo
pan Synuclein antibody (ab53726) | Abcam
High levels of expression have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor ...
http://www.abcam.com/pan-Synuclein-antibody-ab53726.html...

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α/β/γ-synuclein (FL-140) Antibody sc-10717
Mouse, Sncg, 20618, 14 B, Q9Z0F7, N/A. Mouse, Sncb, 104069, 13 B1, Q91ZZ3, N/A. Ordering Information. Product Name, Catalog #, Unit, Price, Qty, Wish List ...
http://www.scbt.com/datasheet-10717-alpha-beta-gamma-synucle...

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AnaSpec: Promotions from AnaSpec
These proteins, along with g-synuclein (SNCG), are members of the synuclein family of small proteins expressed primarily in neural tissue and in some ...
http://www.anaspec.com/products/promotions.asp?col=2&row=3...

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< 다음 5 논문 >
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, SNCG, 6623, 10q23.2, NM_003087 ...
http://www.scbt.com/ko/product.php?datasheet=10698&page=2&to...

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Abgent - Cancer Antibodies - Cancer
AT3970aNEW, SNAI2 monoclonal antibody (M05), ELISA,IF,WB-Ce,WB-Re,WB-Ti, H. AT3980aNEW, SNCG monoclonal antibody (M01), ELISA,WB-Re,WB-Tr, H ...
http://www.abgent.com/products/category/cell_function/cancer...

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α/β/γ-synuclein (FL-140) Antibody sc-10717
Mouse, Sncg, 20618, 14 B, Q9Z0F7, 없음. Mouse, Sncb, 104069, 13 B1, Q91ZZ3, 없음 . 주문정보. 제품명, 카탈로그 번호, 단위, 가격, 수량, 관심상품 ...
http://www.scbt.com/ko/datasheet-10717-alpha-beta-gamma-synu...

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γ-synuclein siRNA (m) sc-42290
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Sncg, 20618, 14 B, Q9Z0F7 ...
http://www.scbt.com/datasheet-42290-gamma-synuclein-sirna-m....

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