Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18333897 |
SOX9 expression is a general feature of basal cell carcinomas and adnexal skin neoplasms, suggesting a contribution of SOX9 to the pathogenesis of these tumors. |
| 18087279 |
The association of SOX9 hypermethylation with tumour progression and clinical outcome suggests its relevant clinical implications at stratifying patients affected with bladder cancer. |
| 15266301 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17615267 |
SOX9 signaling is not essential for LE135-induced chondrogenesis in mesenchymal stem cells derived from osteoarthritis patients. |
| 17532558 |
The embryonic male prostaglandin D synthase (Pgds)/SOX9 pathway is expressed at both the RNA and protein levels in different types of human ovarian tumors. |
| 17702866 |
role of SOX9 in pigmentation emphasizes the impact of SOX proteins in adult tissues. |
| 17360815 |
Sox9 transcriptionally regulates furin expression during chondrogenesis. |
| 11754051 |
A chromosomally normal boy with ACD and his clinical follow-up up to the age of 2 years, in whom a heterozygous SOX9 missense mutation (H165Y) was identified. |
| 12783851 |
Loss of DNA-dependent dimerization of the transcription factor SOX9 as a cause for campomelic dysplasia |
| 15456769 |
SOX9 is a key regulator of CRTL1 |
| 15922909 |
SOX9 may play an important role in the transcriptional activation of the newest collagen gene, COL27A1. |
| 17551083 |
These findings suggest that non-syndromic PRS may be caused by both SOX9 and KCNJ2 dysregulation. |
| 12935820 |
no positive correlation between SOX9 and COL2A1 expression was observed in articular chondrocytes--to the contrary, the expression of COL2A1 was significantly increased in the diseased cells |
| 15896776 |
The SOX9, as a potential melanogenic transcriptional regulator, as its expression level is increased following the down-regulation of BRN2 in differentiated melanoblasts. |
| 12713737 |
SOX9 exerts a bifunctional effect on COL2A1 gene expression in chondrocytes depending on the differentiation state. |
| 15694126 |
the ubiquitin-proteasome proteolytic system degrades Sox9 and regulates its transcriptional activity |
| 15623506 |
Smad3 induces chondrogenesis through the activation of SOX9 via CREB-binding protein/p300 recruitment |
| 15781631 |
Transcription factor SOX9 down-regulates CEA gene expression and, as a probable consequence, induces apoptosis in the human colon carcinoma cell line HT29Cl.16E. |
| 17197889 |
Sox9 is variably expressed in ovarian Sertoli cell tumor and other tumors that are in the differential diagnosis |
| 12128229 |
novel potential role for SOX9 in pancreas development during human embryogenesis and early foetal life |
| 12673561 |
mesenchymal chondrosarcoma showed positive nuclear staining in both primitive mesenchymal and cartilaginous components for Sox9 protein |
| 15192080 |
It is revealed with an in vitro sumoylated Ad4BP/SF-1 that DNA binding activity and interaction with Sox9 ware unaffected. |
| 16109717 |
Sox9 and p300 interact with chromatin and activates transcription via regulation of chromatin modification |
| 17234760 |
Results indicate that SOX9 in prostate basal cells supports the development and maintenance of the luminal epithelium and that a subset of prostate cancer cells may escape basal cell requirements through SOX9 expression. |
| 17409199 |
data support a direct molecular link between the Hh signaling pathway and SOX9 regulation, wherein SHH stimulates SOX9 through its mediator GLI1, and are consistent with a mechanism of SOX9 regulation through distal chromatin interactions |
| 16554309 |
by controlling the cellular concentrations of SOX9, PIAS proteins and sumoylation may be part of a major regulatory system of SOX9 functions |
| 11707075 |
Sequence analysis of the intergenic regions revealed five regulatory elements, E1-E5, 5' to SOX9 and three such elements, E6-E8, 3' to SOX9. |
| 15908194 |
Sox9 promoter is regulated by CCAAT-binding factor through its interaction with two functional CCAAT boxes. |
| 12420222 |
RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition. |
| 12111997 |
demonstration that a novel human gene, KIAA0800, is preferentially expressed in the testis and is transactivated by Sox9 |
| 15240568 |
SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes |
| 15240557 |
Results suggest that SOX9 is necessary and sufficient to specify pyloric sphincter epithelial properties. |
| 11990798 |
discussion of molecular action (REVIEW) |
| 12732631 |
CBP and p300 function as co-activators of Sox9 for cartilage tissue-specific gene expression and chondrocyte differentiation. |
| 15077158 |
SOX9 contributes to growth regulation by mac25 via inhibition of cell growth and promotion of differentiation in prostate tumor |
| 16155402 |
Human SOX9 in undifferentiated mouse ES cells might have dual potentials to induce both chondrogenic commitment and growth capacity in the undifferentiated status. |
| 16791471 |
pediatric and adult high grade tumors display strong nuclear staining for SOX9 |
| 17050539 |
SOX9 mRNA regulation in human articular chondrocytes involves p38 MAPK activation and mRNA stabilization |
| 17289023 |
Here we report that the human SOX9 proximal promoter is also regulated by the cyclic-AMP response element binding protein (CREB) and Sp1. |
