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SPP1
| Symbol: | SPP1 | | Name(s): | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | BNSP, BSPI, ETA-1, MGC110940, OPN | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18317949 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18335026 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18162078 |
Real-time PCR showed that ETOH significantly altered the expression of genes involved in cell adhesion. There was an increase in the expression of alpha and beta Laminins 1, beta Integrins 3 and 5, Secreted phosphoprotein1 and Sarcoglycan epsilon. |
| 18079410 |
OPN is required for the differentiation and activity of myofibroblasts formed in response to the profibrotic cytokine transforming growth factor-beta1. |
| 16741188 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17170369 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17384004 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17439891 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17496055 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17519954 |
Observational study of gene-disease association. (HuGE Navigator) | →View more information from publications. |
Recent Publications on SPP1: |  |
Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture.
BACKGROUND: Osteoporosis is a highly heritable trait. Many candidate genes... | 3rd November, 2009
| McGill University, Montreal, Quebec, Canada.
| Ann Intern Med. 2009 Oct 20;151(8):528-37.
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Circulating mesenchymal stem cells with abnormal osteogenic differentiation in patients with osteoporosis.
OBJECTIVE: While the role of osteoclasts in bone loss has been well... | 31st October, 2009
| University of Verona, Verona, Italy.
| Arthritis Rheum. 2009 Oct 29;60(11):3356-3365.
DOI Direct Link |
Osteopontin: an early innate immune marker of Escherichia coli mastitis harbors genetic polymorphisms with possible links with resistance to mastitis.
BACKGROUND: Mastitis is the most important disease in dairy cows and it... | 31st October, 2009
| Dairy and Swine Research and Development Centre, Agriculture and Agri-Food
| BMC Genomics. 2009 Sep 18;10:444.
DOI Direct Link |
Evidence for different pathways during horizontal gene transfer in competent Bacillus subtilis cells.
Cytological and genetic evidence suggests that the Bacillus subtilis DNA... | 29th October, 2009
| Mikrobiologie, Fakultat fur Biologie, Universitat Freiburg, Freiburg,
| PLoS Genet. 2009 Sep;5(9):e1000630. Epub 2009 Sep 4.
DOI Direct Link |
Conceptus-uterus interactions in pigs: endometrial gene expression in response to estrogens and interferons from conceptuses.
This review highlights information on conceptus-uterus interactions in the... | 24th October, 2009
| Department of Veterinary Integrative Biosciences, College of Veterinary
| Soc Reprod Fertil Suppl. 2009;66:321-32.
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→View more research publications. |
SPP1 results (if any) from reagent suppliers | 
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Anti-SPP1 Polyclonal Antibody
Polyclonal Antibody against SPP1 for use in Immunohistochemistry (Paraffin), Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...
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SPP1 Antibody (C-term)
Western blot analysis of SPP1 Antibody (C-term) (Cat. #AP6555b) in NCI-H460 cell line lysates (35ug/lane). SPP1 (arrow) was detected using the purified Pab. ...
http://www.abgent.com/products/catalog_no/AP6555b_SPP1_Antib...
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Osteopontin Antibody (CT) Osteopontin / SPP1
Osteopontin antibody was raised against a synthetic peptide near the C-terminus of osteopontin.,
http://www.prosci-inc.com/shop/catalog1/Osteopontin-Antibody...
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OPN (AKm2A1) Antibody sc-21742
Mouse, Spp1, 20750, 5 E5, P10923 ... BACKGROUND, Osteopontin (OPN, also designated Bone Sialoprotein 1, Urinary Stone Protein, spp-1, eta-1,
nephropontin, ...
http://www.scbt.com/datasheet-21742-opn-akm2a1-antibody.html...
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6X His tag® antibody - ChIP Grade (ab9108) reviews | Abcam
Strain expressing an untagged version of Spp1. Additional Data. Rating. Excellent 5 stars (out of 5). Additional notes. The lower band mind also be
specific ...
http://www.abcam.com/index.html?pageconfig=reviews&intAbID=9...
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OPN (LFMb-14) Antibody sc-73631
... Protein Accession #, OMIM™ Number. Human, SPP1, 6696, 4q22.1, NM_000582, NM_001040058, NM_001040060 · P10451 · 166490. Mouse, Spp1, 20750, 5 E5, P10923
...
http://www.scbt.com/datasheet-73631-opn-lfmb-14-antibody.htm...
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Anti-Osteopontin antibody produced in goat (O3389) - Datasheet
phosphoprotein 1 (Spp1), bone sialoprotein-1, and early. T lymphocyte activation protein-1 (ETA-1), is a secreted acidic phosphorylated glycoprotein. ...
https://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashe...
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