Recent Publications on : |  |
Genetic variants of BLM interact with RAD51 to increase breast cancer susceptibility.
The role of the familial breast cancer susceptibility genes, BRCA1 and...
Direct Link | 1st November, 2008
| Department of Nursing, Kang-Ning Junior College of Medical Care and
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| Gene-environment interactions in breast cancer.
| 1st November, 2008
| Centre for Molecular Epidemiology, National University of Singapore,
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Skewed X Chromosome Inactivation and Breast and Ovarian Cancer Status: Evidence for X-Linked Modifiers of BRCA1.
Background X chromosome inactivation, which silences gene expression from...
Direct Link | 30th October, 2008
| Affiliations of authors: Cancer and Cell Biology Division (FL, GFK, ABS)
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"BRCAness" Syndrome in Ovarian Cancer: A Case-Control Study Describing the Clinical Features and Outcome of Patients With Epithelial Ovarian Cancer Associated With BRCA1 and BRCA2 Mutations.
PURPOSE: We evaluated the clinical impact of germ-line BRCA1/2 mutations...
Direct Link | 29th October, 2008
| Gynaecological Oncology and Cancer Genetics Units, Royal Marsden Hospital,
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Linking the Cellular Functions of BRCA Genes to Cancer Pathogenesis and Treatment.
Single-gene disorders that predispose to cancer afford a unique window...
Direct Link | 29th October, 2008
| Department of Oncology, University of Cambridge, and the Medical Research
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Classification of rare missense substitutions, using risk surfaces, with genetic- and molecular-epidemiology applications.
Many individually rare missense substitutions are encountered during deep...
Direct Link | 28th October, 2008
| International Agency for Research on Cancer (IARC), Lyon, France.
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Assessment of functional effects of unclassified genetic variants.
Inherited predisposition to disease is often linked to reduced activity of...
Direct Link | 28th October, 2008
| Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester,
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Tumor characteristics as an analytic tool for classifying genetic variants of uncertain clinical significance.
It is important to identify a germline mutation in a patient with an...
Direct Link | 28th October, 2008
| Department of Genetics, University Medical Center Groningen and University
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Locus-specific databases and recommendations to strengthen their contribution to the classification of variants in cancer susceptibility genes.
Locus-specific databases (LSDBs) are curated collections of sequence...
Direct Link | 28th October, 2008
| Vermont Cancer Center and Department of Medicine, University of Vermont,
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In Response.
Concerns have been raised from some investigators about the positive...
Direct Link | 25th October, 2008
| Departments of Obstetrics, Gynecology and Reproductive Science, Yale
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Diagnostic Markers for Ovarian Cancer Screening: Not Ready for Routine Clinical Use.
To the Editor: Given the number of women who are diagnosed with ovarian...
Direct Link | 25th October, 2008
| National Office of Public Health Genomics, Centers for Disease Control and
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The role of magnetic resonance imaging in screening women at high risk of breast cancer.
Most women at very high risk of breast cancer because of a mutation in the...
Direct Link | 23rd October, 2008
| Division of Medical Oncology, Sunnybrook Health Sciences Centre, Toronto,
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| Risk-reduction surgery in BRCA mutation carriers in a Spanish population: adherence and results.
| 23rd October, 2008
| Medical Oncology (Genetic Counselling Unit), Hospital Clinico San Carlos,
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Restoration of CAPAN-1 cells with functional BRCA2 provides insight into the DNA repair activity of individuals who are heterozygous for BRCA2 mutations.
Mutations in the BRCA2 gene are associated with inherited, early-onset...
Direct Link | 23rd October, 2008
| Department of Pathology, University of Colorado Health Sciences Center,
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Prevalence and characteristics of pancreatic cancer in families with BRCA1 and BRCA2 mutations.
A growing body of research describes cancers other than breast and ovarian...
Direct Link | 16th October, 2008
| School of Medicine, University of California, San Francisco, San
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