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STAT5A
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18023521 |
IL-2 selectively enhanced production of IL-10 in HOZOT primarily through activation of STAT5, which synergistically acts with NF-kappaB/NFAT activation, implying a novel regulatory mechanism of IL-10 production in Treg cells. |
| 17938255 |
Following cell exposure to IL-15, phosphorylation of STAT5 was predominantly observed, whereas, following stimulation with IL-21, there was predominant STAT1 and STAT3 activation. |
| 15063762 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17639043 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17846080 |
after tyrosine phosphorylation, STAT5a accumulates in the nucleus because of its retention by DNA binding |
| 18172316 |
The work presented here provides the first evidence of synergy between AR and the prolactin signaling protein Stat5a/b in human prostate cancer cells. |
| 17666591 |
analysis of STAT5, CIS, and SOCS2 interactions with the growth hormone receptor |
| 17922009 |
Acts as a key tumor suppressor by reciprocally inhibiting expression of oncogenic nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) in T-cell anaplastic large cell lymphomas. |
| 17913706 |
Myc down-regulation is a mechanism to activate the Rb pathway in STAT5A-induced senescence |
| 17726024 |
the phosphorylation of Tyr(1077) on LepRb during receptor activation, substantiate the hypothalamic regulation of STAT5 and S6 by leptin, and define the alternate LepRb signaling pathways | →View more information from publications. |
Recent Publications on STAT5A: |  |
A Novel Distal Enhancer Mediates Cytokine Induction of Mouse Rankl Gene Expression.
Chronic inflammatory states are associated with increased bone loss. This... | 3rd November, 2009
| Department of Biochemistry, University of Wisconsin-Madison, Madison,
| Mol Endocrinol. 2009 Oct 30.
DOI Direct Link |
A novel splicing variant form suppresses the activity of full-length signal transducer and activator of transcription 5A.
Signal transducers and activators of transcription (STATs) regulate a... | 29th October, 2009
| Department of Cell Biology, Research Institute for Neurological Diseases
| FEBS J. 2009 Nov;276(21):6312-23. Epub 2009 Sep 28.
DOI Direct Link |
Repeated Treatment with Subtoxic Doses of TRAIL Induces Resistance to Apoptosis through Its Death Receptors in MDA-MB-231 Breast Cancer Cells.
Recombinant human tumor necrosis factor-related apoptosis-inducing ligand... | 22nd October, 2009
| Office of Biotechnology Products, Center for Drug Evaluation and Research,
| Mol Cancer Res. 2009 Oct 20.
DOI Direct Link |
Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A.
Mammary alveologenesis is abrogated in the absence of the transcription... | 17th October, 2009
| Laboratory of Genetics and Physiology, National Institute of Diabetes and
| Genes Dev. 2009 Oct 15;23(20):2382-7.
DOI Direct Link |
Insulin, a key regulator of hormone responsive milk protein synthesis during lactogenesis in murine mammary explants.
Murine milk protein gene expression requires insulin, hydrocortisone, and... | 16th October, 2009
| CRC for Innovative Dairy Products, Department of Zoology, University of
| Funct Integr Genomics. 2009 Oct 15.
DOI Direct Link |
→View more research publications. |
STAT5A results (if any) from reagent suppliers | 
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