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VAMP7


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Symbol:VAMP7
Name(s):vesicle-associated membrane protein 7
Type:protein-coding
Organism:Homo sapiens
Synonyms:SYBL1, TI-VAMP, VAMP-7
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11840509 Observational study of gene-disease association. (HuGE Navigator)
18042464 Our results show that VAMP-7 is a crucial component of granzyme B release and target cell killing in the NK cell line YT-Indy.
14672948 results reported here clarify that a Staf-zinc finger family factor is the major nuclear protein bound to the synaptobrevin-like 1 (SYBL1) promoter region and is responsible for its regulation in HeLa cells
12444103 In ICF (immunodeficiency, centromeric instability, facial abnormalities) syndrome SYBL1 escapes from silencing and this correlates with altered patterns of histone methylation and acetylation.
16430921 Data show that the insensitivity of TI-VAMP to botulinum neurotoxin B relies on at least 12 amino acid changes versus VAMP-2, which are scattered along an interface of 22 amino acid residues in length.
11840509 A G-->C transversion in a regulatory region was found to be associated with bipolar affective disorder.
16195891 VAMP-7 is involved in the constitutive exocytosis as a slow, minor v-SNARE, but not in lysosomal transport

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDsynaptosomal-associated protein 25 isoform SNAP25Avesicle-associated membrane protein 7--Pubmed
HPRDsynaptosomal-associated protein 25 isoform SNAP25Avesicle-associated membrane protein 7--Pubmed
HPRDsyntaxin 1Avesicle-associated membrane protein 7--Pubmed
HPRDsyntaxin 1Avesicle-associated membrane protein 7--Pubmed
HPRDsyntaxin 3vesicle-associated membrane protein 7--Pubmed
HPRDSynaptobrevin like protein 1syntaxin 7--Pubmed
HPRDvesicle-associated membrane protein 7Syntaxin 7--Pubmed
BINDvesicle-associated membrane protein 7-SNAP23 interacts with VAMP7.-Pubmed
BINDvesicle-associated membrane protein 7DNAJC5Csp1 interacts with VAMP7. This interaction was modeled on a demonstrated interaction between cow Csp1, and human VAMP7.-Pubmed
HPRDvesicle-associated membrane protein 7synaptosomal-associated protein 23 isoform SNAP23A--Pubmed

Recent Publications on VAMP7:

Pubmed Logo
Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking.
SNARE (Soluble N-ethylmaleimide-sensitive factor attachment protein...
20th October, 2009
Membrane Traffic in Neuronal and Epithelial Morphogenesis', INSERM U950, FEBS Lett. 2009 Oct 20.
DOI Direct Link
TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways.
During reticulocyte maturation, some membrane proteins and organelles that...
29th September, 2009
Laboratorio de Biologia Celular y Molecular, Instituto de Histologia y Biochim Biophys Acta. 2009 Sep 23.
DOI Direct Link
Variations in the requirement for v-SNAREs in GLUT4 trafficking in adipocytes.
Vesicle transport in eukaryotic cells is regulated by SNARE proteins,...
18th September, 2009
National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese J Cell Sci. 2009 Oct 1;122(Pt 19):3472-80.
DOI Direct Link
The delivery of endocytosed cargo to lysosomes.
In mammalian cells, endocytosed cargo that is internalized through...
17th September, 2009
Cambridge Institute for Medical Research and Department of Clinical Biochem Soc Trans. 2009 Oct;37(Pt 5):1019-21.
DOI Direct Link
Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth.
The vesicular soluble N-ethylmaleimide-sensitive factor attachment protein...
12th September, 2009
Membrane Traffic in Neuronal & Epithelial Morphogenesis, INSERM U950, EMBO Rep. 2009 Oct;10(10):1117-24. Epub 2009 Sep 11.
DOI Direct Link

View more research publications.

VAMP7 results (if any) from reagent suppliers

Google CSE Logo
SYBL1 antibody [158.2] (ab36195) | Abcam
Component of the SNARE complex composed of STX7, STX8, VAMP7 and VTI1B that is ... Flowerdew SE & Burgoyne RD A VAMP7/Vti1a SNARE complex distinguishes a ...
http://www.abcam.com/SYBL1-antibody-158-2-ab36195.html...

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Syntaxin Antibody / Syntaxin Antibodies
A proposed SNARE complex between Syntaxin 7 and VAMP7 or VAMP8 may regulate the fusion events that eventually lead to melanogenesis. BACKGROUND REFERENCES ...
http://www.scbt.com/table-syntaxin.html...

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alpha Adaptin antibody [AP6] (ab2730) | Abcam
Molecular basis for the sorting of the SNARE VAMP7 into endocytic clathrin- coated vesicles by the ArfGAP Hrb. Cell 134:817-27 (2008). ICC/IF; Rat. ...
http://www.abcam.com/alpha-adaptin-antibody-ap6-ab2730.html...

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TI-VAMP Antibody / TI-VAMP Antibodies
PRODUCT NAME, CATALOG #, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. TI-VAMP (D-17) Antibody, sc-32593, goat IgG, internal (h), WB, IF, ELISA, m, r, h ...
http://www.scbt.com/table-ti-vamp.html...

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Membrin antibody [4HAD6 ] (ab13511) | Abcam
Flowerdew SE & Burgoyne RD A VAMP7/Vti1a SNARE complex distinguishes a non- conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium
...
http://www.abcam.com/Membrin-antibody-4HAD6-ab13511.html...

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Anti-Vesicle Associated Membrane Protein 4 (V4514) - Datasheet
myotubes (VAMP-5),9 and lysosomes (VAMP-7).6. Reagent. Anti-Vesicle Associated Membrane Protein 4 is supplied as 100 µg of affinity isolated antibody in ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...

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Syntaxin Antibody / Syntaxin Antibodies
A proposed SNARE complex between Syntaxin 7 and VAMP7 or VAMP8 may regulate the fusion events that eventually lead to melanogenesis. Referencias del fondo ...
http://www.scbt.com/es/table-syntaxin.html...

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