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TAC3
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17175032 |
Observational study and meta-analysis of gene-disease association. (HuGE Navigator) |
| 17448763 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17561251 |
Placental mRNA expression of NKB was significantly higher after term and preterm labor (P<0.001) than cesarean section, and highest after preterm labor |
| 16709596 |
Results determined the placenta to be the main site of TAC3 expression with levels 2.6-fold higher than the brain and TAC3 expression was found to be significantly higher in pre-eclamptic placenta (1.7-fold, P < 0.05) than in normal controls. |
| 14634580 |
Higher neurokinin B concentrations in normotensive pregnant women may be due to the advanced gestational age and/or the result of a negative interaction of other vasoactive substances. The role of neurokinin B in preeclampsia remains to be determined. |
| 15317475 |
three-dimensional structure |
| 12727971 |
study demonstrates a paracrine role for neurokinin B in the regulation of fetal placental vascular tone |
| 14700748 |
NKB plays a role in the maintenance of high placental blood flow in normal pregnancy |
| 15123623 |
mode of vascular regulation in which GATA-1 controls NK-B synthesis in erythroid cells |
Recent Publications on TAC3: |  |
The human neurokinin B gene, TAC3, and its promoter are regulated by Neuron Restrictive Silencing Factor (NRSF) transcription factor family.
We have previously shown that one of the major determinants directing the... | 15th October, 2009
| Department of Human Anatomy and Cell Biology, School of Biomedical
| Neuropeptides. 2009 Aug;43(4):333-40. Epub 2009 Jun 17.
DOI Direct Link |
The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism.
Idiopathic hypogonadotropic hypogonadism (IHH) has an incidence of 1-10... | 27th August, 2009
| Department of Molecular and Cellular Pharmacology, Leonard M. Miller
| Nat Rev Endocrinol. 2009 Oct;5(10):569-76. Epub 2009 Aug 25.
DOI Direct Link |
The genetics of idiopathic hypogonadotropic hypogonadism:unraveling the biology of human sexual development.
Idiopathic Hypogonadotropic Hypogonadism (IHH), a syndrome of GnRH... | 22nd May, 2009
| Pediatric Endocrine Division, Department of Pediatrics, Brooklyn, New York
| Pediatr Endocrinol Rev. 2009 Mar;6(3):395-404.
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TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction.
The timely secretion of gonadal sex steroids is essential for the... | 3rd April, 2009
| Cukurova University, Faculty of Medicine, Department of Pediatric
| Nat Genet. 2009 Mar;41(3):354-8. Epub 2008 Dec 11.
DOI Direct Link |
Laminin-1-derived scrambled peptide AG73T disaggregates laminin-1-induced ovarian cancer cell spheroids and improves the efficacy of cisplatin.
We found previously that the laminin-1-derived synthetic peptide AG73... | 28th May, 2008
| Department of Obstetrics and Gynecology, Faculty of Medical Science,
| Int J Oncol. 2008 Mar;32(3):673-81.
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→View more research publications. |
TAC3 results (if any) from reagent suppliers | 
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eHandbook 001_050.indd
encoded by three genes named TAC1, TAC3 and TAC4 by the Human Genome Organiza- ... is the only tachykinin derived from the TAC3. (PPT-B) gene. ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/RBI_Hand...
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Neurokinin B siRNA (h) sc-106300
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, TAC3, 6866, 12q13.3, NM_001006667, ...
http://www.scbt.com/ko/datasheet-106300-neurokinin-b-sirna-h...
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CPG1000 dA(tac)
Sigma-Aldrich Online Catalog Product List: CPG1000 dA(tac)
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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Preprotachykinin Antibody / Preprotachykinin Antibodies
Preprotachykinin Antibody / Preprotachykinin Antibodies.
http://www.scbt.com/pt/table-preprotachykinin.html...
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CPG1000 dG(tac)
Sigma-Aldrich Online Catalog Product List: CPG1000 dG(tac)
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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