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TAF1


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Symbol:TAF1
Name(s):TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
Type:protein-coding
Organism:Homo sapiens
Synonyms:BA2R, CCG1, CCGS, DYT3, KAT4, N-TAF1, NSCL2, OF, P250, TAF2A, TAFII250
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17952504 Thirty-eight exons code for TAF1. Five downstream exons of yet unknown function can either form transcripts with TAF1 exons or be transcribed independently. Splice variants can include d plus at least 12 TAF1 exons.
16113828 Observational study of gene-disease association. (HuGE Navigator)
16155788 Observational study of gene-disease association. (HuGE Navigator)
17327284 Observational study of gene-disease association. (HuGE Navigator)
15978108 Observational study of gene-disease association. (HuGE Navigator)
12876631 Observational study of gene-disease association. (HuGE Navigator)
12958613 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
14651335 Observational study of gene-disease association. (HuGE Navigator)
14717966 Observational study of gene-disease association. (HuGE Navigator)
14719174 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDHuman bax gene, 5' region.-TAF1 (TAFII250) interacts with the Bax promoter.-Pubmed
HPRDcyclin D1TBP-associated factor 1 isoform 1--Pubmed
HPRDcyclin D1TBP-associated factor 1 isoform 1--Pubmed
BINDcyclin D1TBP-associated factor 1 isoform 2TAFII250 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between TAFII250 from human and Cyclin D1 from mouse.-Pubmed
HPRDcyclin ATBP-associated factor 1 isoform 1--Pubmed
HPRDcyclin ATBP-associated factor 1 isoform 1--Pubmed
HPRDEwing sarcoma breakpoint region 1 isoform EWSTBP-associated factor 1 isoform 1--Pubmed
HPRDEwing sarcoma breakpoint region 1 isoform EWSTBP-associated factor 1 isoform 1--Pubmed
HPRDc-FosTBP-associated factor 1 isoform 1--Pubmed
HPRDv-fos FBJ murine osteosarcoma viral oncogene homologTFIID--Pubmed

Recent Publications on TAF1:

Pubmed Logo
The monogenic primary dystonias.
Presently, 17 distinct monogenic primary dystonias referred to as...
30th October, 2009
Institut fur Humangenetik, Justus-Liebig-Universitat, Schlangenzahl 14, Brain. 2009 Aug;132(Pt 8):2005-25. Epub 2009 Jul 3.
DOI Direct Link
Cooperative binding of two acetylation marks on a histone tail by a single bromodomain.
A key step in many chromatin-related processes is the recognition of...
17th October, 2009
European Molecular Biology Laboratory, Grenoble Outstation, 6 rue Jules Nature. 2009 Oct 1;461(7264):664-8.
DOI Direct Link
D-Serine exposure resulted in gene expression changes implicated in neurodegenerative disorders and neuronal dysfunction in male Fischer 344 rats.
D-Serine, an endogenous amino acid, is involved in many physiological...
7th August, 2009
Oak Ridge Institute for Science and Education, Columbus, OH 43201, USA. Arch Toxicol. 2009 Aug;83(8):747-62. Epub 2009 Feb 11.
DOI Direct Link
Complicated recessive dystonia parkinsonism syndromes.
In addition to pure PD and pure dystonic syndromes, there are a group of...
29th July, 2009
Sobell Department of Motor Neuroscience and Movement Disorders, Institute Mov Disord. 2009 Mar 15;24(4):490-9.
DOI Direct Link
Control of alternative splicing by signal-dependent degradation of splicing-regulatory proteins.
Alternative pre-mRNA splicing is a major gene expression regulatory...
19th June, 2009
Department of Pharmacology, University of Wisconsin School of Medicine and J Biol Chem. 2009 Apr 17;284(16):10737-46. Epub 2009 Feb 13.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
4761064 Color-corrected lens systems
5870228 Projection lenses having larger back focal length to focal length ratios
5877202 Indole derivatives useful to treat estrogen-related neoplasms and disorders
5900987 Zoom projection lenses for use with pixelized panels
5910412 Method for identifying the sex of spinach by DNA markers

View more patents.

TAF1 results (if any) from reagent suppliers

Google CSE Logo
TAF1 antibody, TAF1 (TAF1 RNA polymerase II. TATA box binding ...
Buy quality rabbit TAF1 antibody (interacts with human), anti-TAF1, TAF1 (TAF1 RNA polymerase II. TATA box binding protein (TBP)-associated factor.
http://www.genwaybio.com/product_info.php?products_id=42223...

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KAT4 / TBP Associated Factor 1 antibody - ChIP Grade (ab28450) | Abcam
KAT4 / TAF1 also known as TBP Associated Factor 1 is the largest subunit of the transcription factor TFIID. Studies have shown that KAT4 has serine/th...
http://www.abcam.com/KAT4-TBP-Associated-Factor-1-antibody-C...

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TAF1 monoclonal antibody (M01)
TAF1 (NP_004597, 1784 a.a. ~ 1894 a.a) partial recombinant protein with GST tag. ... Detection limit for recombinant GST tagged TAF1 is approximately ...
http://www.abgent.com/products/catalog_no/AT4136a_TAF1_monoc...

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TAF1 48 antibodies: Chromatin and Nuclear Signaling ...
TAF1 48 antibodies. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab37430 · TAF1 48 antibody. WB. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=159510&pt=1&c=900&ei=&mu=r...

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Certificate of Analysis Product: Affinity Purified Anti ...
Subunit 1 (TAF1) is the largest component and core scaffold of ... RB1, interacts with the N-terminal domain of TAF1 and inhibits its ...
http://www.rockland-inc.com/objects/catalog/product/extras/1...

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RB1 antibody, retinoblastoma 1 (including osteosarcoma) (RB1 ...
Inhibits the intrinsic kinase activity of TAF1. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally ...
http://www.genwaybio.com/product_info.php?products_id=60054...

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Protein Modification - Ubiquitination Antibody
AT4136aNEW, TAF1 monoclonal antibody (M01), ELISA,S-ELISA,WB-Re, H. AT4137aNEW, TAF1 monoclonal antibody (M02), ELISA,WB-Ce,WB-Re, H ...
http://www.abgent.com/products/category/protein_modification...

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