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TAF4
| Symbol: | TAF4 | | Name(s): | TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | FLJ41943, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18206971 |
TAF4b incorporation into TFIID induces an open conformation at the lobe involved in TFIIA & putative activator interactions, correlating with differential activator-dependent transcription & promoter recognition by 4b/4-IID. |
| 12237304 |
Data present the crystal structure of a complex formed by the interacting domains from two subunits of the general transcription factor TFIID, the human TATA binding protein-associated factors hTAF4 (hTAF(II)135) and hTAF12 (hTAF(II)20). |
| 12810884 |
trans-activation of promoters by simian virus 40 small t-antigen may depend on a consensus TATA motif and such promoters recruit the general transcription factor hTAF(II)130/135 |
| 11988536 |
huntingtin interacts with Sp1 and TAFII130; transcriptional activity of SP1 and TAFII130 disrupted in early Huntingtin's Disease |
Recent Publications on TAF4: |  |
TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes.
The major core promoter-binding factor in polymerase II transcription... | 29th July, 2009
| Department of Biological Chemistry, Weizmann Institute of Science, Rehovot
| J Biol Chem. 2009 Sep 25;284(39):26286-96. Epub 2009 Jul 27.
DOI Direct Link |
TAF4 takes flight.
The major core promoter-binding factor in polymerase II transcription... | 28th February, 2009
| Department of Biology and Rosenstiel Basic Medical Sciences Research
| Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1295-6. Epub 2009 Jan 27.
DOI Direct Link |
Wnt signaling targets ETO coactivation domain of TAF4/TFIID in vivo.
Understanding the diverse activities of the multisubunit core promoter... | 14th February, 2009
| Howard Hughes Medical Institute, Li Ka-Shing Center for Biomedical and
| Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):55-60. Epub 2008 Dec 30.
DOI Direct Link |
Structural changes in TAF4b-TFIID correlate with promoter selectivity.
Proper ovarian development requires the cell type-specific transcription... | 22nd March, 2008
| Howard Hughes Medical Institute, Li Ka-Shing Center for Biomedical and
| Mol Cell. 2008 Jan 18;29(1):81-91.
DOI Direct Link |
Retinoic acid induces TGFbeta-dependent autocrine fibroblast growth.
To evaluate the role of murine TFIID subunit TAF4 in activation of... | 7th February, 2008
| Institut de Genetique et de Biologie Moleculaire et Cellulaire,
| Oncogene. 2008 Jan 17;27(4):477-89. Epub 2007 Jul 16.
DOI Direct Link |
→View more research publications. |
TAF4 results (if any) from reagent suppliers |
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Taf4 antibodies: Chromatin and Nuclear Signaling > Transcription ...
Taf4 antibodies. ... Taf4 antibody [305C2a]. WB, Dot. Images. Mouse monoclonal. Reacts with: Hu. Terms and conditions · Legal · Privacy policy ...
http://www.abcam.com/index.html?t=124642&pt=1&c=3579&ei=&mu=...
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TAF II p130 (4A6) Antibody sc-736
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, TAF4, 6874, 20q13.33, NM_003185 ...
http://www.scbt.com/datasheet-736-taf-ii-p130-4a6-antibody.h...
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Yeast research antibodies | Abcam
... SWI2 / SNF2 antibody (ab22012) · SWI2 / SNF2 antibody (ab22013) · TAF10 antibody (ab64061) · TAF11 antibody (ab64066) · Taf4 antibody (ab63910) ...
http://www.abcam.com/index.html?pageconfig=resource&rid=1199...
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TAF II p135 siRNA (h) sc-76626
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, TAF4, 6874, 20q13.33, NM_003185 ...
http://www.scbt.com/ja/datasheet-76626-taf-ii-p135-sirna-h.h...
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Abcam antibodies and reagents product map
... TUSC2 antibodies (1) · TZFP antibodies (2) · TZFP proteins and peptides (1) · Taf4 antibodies (5) · Tbx2 antibodies (6) · Tbx2 proteins and peptides (2) ...
http://www.abcam.com/index.html?c=250...
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TAF II p135 (22) Antibody sc-136093
... Numero de acesso de isoformas de RNA mensageiro, Numero de acesso de proteina, OMIM&trande; Numero. Humano, TAF4, 6874, 20q13.33, O00268 ...
http://www.scbt.com/pt/datasheet-136093-taf-ii-p135-22-antib...
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TAF II p135 (22) Antibody sc-136093
种属, 基因名称, 基因ID, 染色质位置, 亚型(mRNA)即位号码, 蛋白质即位号码, OMIM™ 号码. 人类, TAF4, 6874, 20q13.33, O00268 ...
http://www.scbt.com/zh/datasheet-136093-taf-ii-p135-22-antib...
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