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TAF12
| Symbol: | TAF12 | | Name(s): | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | TAF2J, TAFII20 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 12237304 |
Data present the crystal structure of a complex formed by the interacting domains from two subunits of the general transcription factor TFIID, the human TATA binding protein-associated factors hTAF4 (hTAF(II)135) and hTAF12 (hTAF(II)20). |
| 15601843 |
histone fold domain mediated interaction enhances the DNA binding activity of each of the TAF6-TAF9 and TAF4b-TAF12 pairs and of a histone-like octamer complex composed of the four TAFs |
| 17268553 |
TAF12 hitherto regarded as RNA polymerase II (RNAP II)-specific was found to be also involved in RNAP I transcription. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| BIND | Transcription initiation factor TFIID subunit 4B. | TAF12 RNA polymerase II, TATA box binding protein-associated factor, 20 kD | TAF4B (hTAF4b) interacts with TAF12 (hTAF12). | - | Pubmed |
| HPRD | TBP-associated factor 5 | TAF12 RNA polymerase II, TATA box binding protein-associated factor, 20 kD | - | - | Pubmed |
| HPRD | TBP-associated factor 5 | TAF12 RNA polymerase II, TATA box binding protein-associated factor, 20 kD | - | - | Pubmed |
| HPRD | TBP-related factor 10 | Transcription initiation factor TFIID subunit 12 | - | - | Pubmed |
| HPRD | TBP-related factor 10 | TAF12 RNA polymerase II, TATA box binding protein-associated factor, 20 kD | - | - | Pubmed |
| HPRD | TBP-associated factor 11 | TAF12 RNA polymerase II, TATA box binding protein-associated factor, 20 kD | - | - | Pubmed |
| HPRD | TBP-associated factor 11 | TAF12 RNA polymerase II, TATA box binding protein-associated factor, 20 kD | - | - | Pubmed |
| BIND | TAF12 RNA polymerase II, TATA box binding protein-associated factor, 20 kD | activating transcription factor 7 | TAF12 (hsTAF12) interacts ATF7. | - | Pubmed |
Recent Publications on TAF12: |  |
TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes.
The major core promoter-binding factor in polymerase II transcription... | 29th July, 2009
| Department of Biological Chemistry, Weizmann Institute of Science, Rehovot
| J Biol Chem. 2009 Sep 25;284(39):26286-96. Epub 2009 Jul 27.
DOI Direct Link |
Production and isotope labeling of antimicrobial peptides in Escherichia coli by means of a novel fusion partner that enables high-yield insoluble expression and fast purification.
A method is presented that allows efficient production of antimicrobial... | 2nd May, 2009
| Institut de Chimie, Universite Louis Pasteur, CNRS UMR 7177, 67070
| J Pept Sci. 2009 Apr;15(4):278-84.
DOI Direct Link |
TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation.
Many studies have detailed the repressive effects of DNA methylation on... | 28th March, 2009
| Division of Molecular Biology of the Cell II, German Cancer Research
| Mol Cell. 2009 Feb 13;33(3):344-53.
DOI Direct Link |
p38beta2-mediated phosphorylation and sumoylation of ATF7 are mutually exclusive.
The ubiquitous activating transcription factor (ATF) 7 binds as a... | 18th December, 2008
| Universite de Strasbourg I, Institut Gilbert Laustriat, CNRS-UMR7175,
| J Mol Biol. 2008 Dec 26;384(4):980-91. Epub 2008 Oct 11.
DOI Direct Link |
TATA box-binding protein-associated factor 12 is important for RAS-induced transformation properties of colorectal cancer cells.
Activating mutations in the RAS proto-oncogene result in constant... | 30th August, 2008
| Laboratory of Signal Mediated Gene Expression, Institute of Biological
| Mol Cancer Res. 2008 Jun;6(6):1071-83.
DOI Direct Link |
→View more research publications. |
TAF12 results (if any) from reagent suppliers | 
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TAF II p20 siRNA (m) sc-106595
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. マウス, Taf12, 66464, 4 D2.3, Q8VE65 ...
http://www.scbt.com/ja/datasheet-106595-taf-ii-p20-sirna-m.h...
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Abgent - Transcription and Regulation Antibodies ...
AT4141aNEW, TAF11 monoclonal antibody (M06), ELISA,IF,S-ELISA,WB-Ce,WB-Re, H. AT4142aNEW, TAF12 monoclonal antibody (M11), ELISA,WB-Ce,WB-Re, H ...
http://www.abgent.com/products/category/nuclear_signaling/tr...
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TAF II p20 siRNA (h) sc-88359
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, TAF12, 6883, 1p35.3, NM_005644 ...
http://www.scbt.com/ko/datasheet-88359-taf-ii-p20-sirna-h.ht...
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Abcam antibodies and reagents product map
MECT1 antibodies (2) · SNAP45 antibodies (3) · STAF65 gamma antibodies (1) · TAF10 antibodies (4) · TAF11 antibodies (3) · TAF12 antibodies (2) ...
http://www.abcam.com/index.html?c=250...
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TAF Basal Transcription Factor Antibody / TAF Basal Transcription ...
TAF Basal Transcription Factor Antibody / TAF Basal Transcription Factor Antibodies.
http://www.scbt.com/ja/table-taf_basal_transcription_factor....
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TAF II p20 siRNA (m) sc-106595
种属, 基因名称, 基因ID, 染色质位置, 亚型（mRNA）即位号码, 蛋白质即位号码, OMIM™ 号码. 小鼠, Taf12, 66464, 4 D2.3, Q8VE65 ...
http://www.scbt.com/zh/datasheet-106595-taf-ii-p20-sirna-m.h...
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Chromosome 4- Santa Cruz Biotechnology, Inc.
Taf12 · 66464, 4 D2.3, Q8VE65 · TAF II p20 · sc-106595 · NM_025579 · 9530096D07Rik · 242681, 4 D2.3, NP_001075120 · Rab 42 · sc-152647 · NM_001081651
...
http://www.scbt.com/ja/chromosome.php?number=4&page=24&speci...
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