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TAL1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17910069 |
characterize the assembly of a five-component complex containing TAL1, LMO2, Ldb1, E12, and DNA. The bHLH domains of TAL1 and E12 alone primarily formed helical homodimers, but together formed heterodimers, to which LMO2 bound with high affinity |
| 17962192 |
Operation of cullin-based ubiquitin ligase complexes and potential means by which Notch and Tal1/SCL regulate eukaryotic development. |
| 17878155 |
the SCL-LMO2 interaction couples protein stabilization with higher order protein complex assembly, thus providing a powerful means of modulating the stoichiometry and spatiotemporal activity of SCL complexes |
| 17507663 |
CD3epsilon-mediated signal transduction pathway is essential for this transformation process |
| 16298389 |
PU.1, in addition to its positive role in TAL-1 expression in early hematopoietic progenitors, may also act as a mediator of TAL-1 silencing in some hematopoietic lineages |
| 16778171 |
TAL1 modulates NFKB1 expression and an NF-kappaB-dependent transcriptional program in a subset of human T-cell leukemia cells. |
| 16621969 |
TAL1 may act as a bifunctional transcriptional regulator (activator and repressor) at the top of a complex regulatory network that disrupts normal T-cell homeostasis and contributes to leukemogenesis. |
| 15086455 |
Possible role for SCL in renal vasculogenesis. Undifferentiated mesenchymal cells expressing SCL during early nephrogenesis might represent putative progenitors that can simultaneously give rise to kidney, blood, and endothelium. |
| 12010791 |
SCL locus can rescue knockout scl(-/-) mice |
| 12239153 |
regulates c-kit expression in hematopoietic cells through functional interaction with Sp1 | →View more information from publications. |
Recent Publications on TAL1: |  |
Scl regulates the quiescence and the long-term competence of hematopoietic stem cells.
The majority of long term reconstituting hematopoietic stem cells (LT-HSC)... | 24th October, 2009
| Institute of Research in Immunology and Cancer (IRIC), Montreal, Canada;
| Blood. 2009 Oct 22.
DOI Direct Link |
E box motifs as mediators of proviral latency of human retroviruses.
The palindromic sequence motifs (CANNTG) known as E boxes are considered... | 17th October, 2009
| Institut de Biologia Molecular Barcelona IBMB-CSIC, Parc Cientific de
| Retrovirology. 2009 Sep 16;6:81.
DOI Direct Link |
Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors.
The TAL1 (or SCL) gene, originally discovered through its involvement by a... | 6th October, 2009
| Department of Medicine, Vanderbilt University Medical Center, Nashville,
| Biochem Biophys Res Commun. 2009 Dec 11;390(2):295-301. Epub 2009 Sep 30.
DOI Direct Link |
Analysis of circulating hem-endothelial marker RNA levels in preterm infants.
BACKGROUND: Circulating endothelial cells may serve as novel markers of... | 3rd October, 2009
| Neonatal Department, Chaim Sheba Medical Center, Tel Aviv University, Tel
| BMC Pediatr. 2009 Jun 25;9:42.
DOI Direct Link |
A novel translocation t(1;5)(p32;q31) that was not associated with the TAL1 rearrangement in a case of T lymphoblastic leukemia/lymphoma.
Chromosome 1 band p32 (1p32) aberrations are common in T lymphoblastic... | 26th September, 2009
| Department of Laboratory Medicine, Yeungnam University College of
| Korean J Lab Med. 2009 Jun;29(3):199-203.
DOI Direct Link |
→View more research publications. |
TAL1 results (if any) from reagent suppliers | 
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p-TAL1 (Ser 122) Antibody sc-12962
TAL1 shRNA (h) Lentiviral Particles, sc-36608-V, 200 µl, $595. TAL1 shRNA (m) Lentiviral Particles, sc-36609-V, 200 µl ...
http://www.scbt.com/datasheet-12962-p-tal1-ser-122-antibody....
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TAL1 Antibody (T90)
Western blot analysis of anti-TAL1 Antibody (T90) (Cat.#AP2754a) in Jurkat cell line lysates (35ug/lane). TAL1 (arrow) was detected using the purified Pab. ...
http://www.abgent.com/products/catalog_no/AP2754a_TAL1_Antib...
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Tal1 antibodies: Stem Cells > Hematopoietic Progenitors ...
Tal1 antibodies. ... Tal1 antibody. IHC-P, WB, ELISA. Images. Rabbit polyclonal. Reacts with: Hu, Ms. Terms and conditions · Legal · Privacy policy ...
http://www.abcam.com/index.html?t=73445&pt=1&c=4530&ei=&mu=r...
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TAL Antibody / TAL Antibodies
TAL1 (C-21) Antibody, sc-12984, goat IgG, C-terminus (h), WB, IP, IF, ... p-TAL1 (Ser 122) Antibody, sc-12962, goat IgG, Ser 122 (h), WB, IF, ELISA, m, r, h ...
http://www.scbt.com/table-tal.html...
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SCL/Tal1 - R&D Systems
SCL, also known as Tal1 (T cell acute lymphocytic leukemia-1 protein), is a basic helix-loop-helix transcription factor. It regulates hematopoiesis ...
http://www.rndsystems.com/molecule_detail.aspx?m=3109...
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p-TAL1 (Ser 122) Antibody sc-12962
p-TAL1 (Ser 122) P, sc-12962 P (peptide), 100 µg/0.5 ml, $58. p-TAL1 (Ser 122) X , sc-12962 X ... TAL1 shRNA (h) Lentiviral Particles, sc-36608-V, 200 µl ...
http://www.scbt.com/ko/datasheet-12962-p-tal1-ser-122-antibo...
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Human SCL MAb (Clone 333803)
leukemia 1 (Tal1), is a basic helix-loop-helix transcription factor. Its expression is essential for hematopoietic lineage commitment of the
hemangioblast. ...
http://www.rndsystems.com/pdf/MAB3360.pdf...
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