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TAP1
| Symbol: | TAP1 | | Name(s): | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | ABC17, ABCB2, APT1, D6S114E, FLJ26666, FLJ41500, PSF1, RING4, TAP1*0102N, TAP1N | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18248301 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18342853 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17875943 |
Data suggest that CBP-mediated histone H3 acetylation normally relaxes the chromatin structure around the TAP-1 promoter region, allowing transcription. |
| 11096258 |
Observational study of gene-disease association. (HuGE Navigator) |
| 11194890 |
Observational study of gene-disease association. (HuGE Navigator) |
| 11250043 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 11250044 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 11591192 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 11737038 |
Observational study of gene-disease association. (HuGE Navigator) |
| 11775239 |
Observational study of genotype prevalence and gene-disease association. (HuGE Navigator) | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | protein disulfide isomerase-associated 3 precursor | Transporter 1 ATP binding cassette, subfamily B | - | - | Pubmed |
| HPRD | major histocompatibility complex, class I, F precursor | transporter 1, ATP-binding cassette, sub-family B | - | - | Pubmed |
| HPRD | major histocompatibility complex, class I, G precursor | transporter 1, ATP-binding cassette, sub-family B | - | - | Pubmed |
| HPRD | transporter 1, ATP-binding cassette, sub-family B | tapasin isoform 1 precursor | - | - | Pubmed |
Recent Publications on TAP1: |  |
TLR9 activation increases TAP-independent vesicular MHC class I processing in vivo.
Cross-presentation of soluble protein antigens on major histocompatibility... | 31st October, 2009
| Microbiology, Tumor and Cell Biology (MTC), Karolinska Institute, 171 77
| Scand J Immunol. 2009 Nov;70(5):431-8.
DOI Direct Link |
What is the role of alternate splicing in antigen presentation by major histocompatibility complex class I molecules?
The expression of major histocompatibility complex (MHC) class I molecules... | 16th October, 2009
| Department of Immunology, Roswell Park Cancer Institute, Elm and Carlton
| Immunol Res. 2009 Oct 15.
DOI Direct Link |
Association of HLA class I antigen abnormalities with disease progression and early recurrence in prostate cancer.
Defects in HLA class I antigen processing machinery (APM) component... | 13th October, 2009
| Institute of Medical Immunology, Martin Luther University
| Cancer Immunol Immunother. 2009 Oct 7.
DOI Direct Link |
Specific CD8 T Cells in Ige-mediated Allergy Correlate with Allergen Dose and Allergic Phenotype.
RATIONALE: Studies in humans and rodents have indicated a causative role... | 10th October, 2009
| Department of Dermatology and Allergy, Biederstein, Technische Universitat
| Am J Respir Crit Care Med. 2009 Oct 8.
DOI Direct Link |
Maturation pathways of dendritic cells determine TAP1 and TAP2 levels and cross-presenting function.
Ability to cross-present exogenous antigens in the human leukocyte antigen... | 9th October, 2009
| Department of Otolaryngology, University of Pittsburgh Cancer Institute,
| J Immunother. 2009 Jun;32(5):465-73.
DOI Direct Link |
→View more research publications. |
TAP1 results (if any) from reagent suppliers | 
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Search Bioportfolio and other Life Science Sites for TAP1,
or search for TAP1 on BioPortfolio's antibody search engine.
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