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TAP2


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Symbol:TAP2
Name(s):transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Type:protein-coding
Organism:Homo sapiens
Synonyms:ABC18, ABCB3, APT2, D6S217E, PSF2, RING11
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18248301 Observational study of gene-disease association. (HuGE Navigator)
18309376 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18071882 Observational study of gene-disease association. (HuGE Navigator)
11096258 Observational study of gene-disease association. (HuGE Navigator)
11229461 Observational study of gene-disease association. (HuGE Navigator)
11294565 Observational study of genotype prevalence. (HuGE Navigator)
11494532 Observational study of gene-environment interaction. (HuGE Navigator)
11737038 Observational study of gene-disease association. (HuGE Navigator)
11775239 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
11916171 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDmajor histocompatibility complex, class I, C precursortransporter 2, ATP-binding cassette, sub-family B isoform 1--Pubmed
HPRDmajor histocompatibility complex, class I, G precursortransporter 2, ATP-binding cassette, sub-family B isoform 1--Pubmed
HPRDtransporter 2, ATP-binding cassette, sub-family B isoform 1tapasin isoform 1 precursor--Pubmed

Recent Publications on TAP2:

Pubmed Logo
The peptide-loading complex--antigen translocation and MHC class I loading.
A large and dynamic membrane-associated machinery orchestrates the...
3rd November, 2009
Institute of Biochemistry, Biocenter, Center for Membrane Proteomics (CMP) Biol Chem. 2009 Aug;390(8):783-94.
DOI Direct Link
What is the role of alternate splicing in antigen presentation by major histocompatibility complex class I molecules?
The expression of major histocompatibility complex (MHC) class I molecules...
16th October, 2009
Department of Immunology, Roswell Park Cancer Institute, Elm and Carlton Immunol Res. 2009 Oct 15.
DOI Direct Link
Association of HLA class I antigen abnormalities with disease progression and early recurrence in prostate cancer.
Defects in HLA class I antigen processing machinery (APM) component...
13th October, 2009
Institute of Medical Immunology, Martin Luther University Cancer Immunol Immunother. 2009 Oct 7.
DOI Direct Link
MUTYH-associated polyposis carcinomas frequently lose HLA class I expression - a common event amongst DNA-repair-deficient colorectal cancers.
Human leukocyte antigen (HLA) class I expression defects frequently occur...
10th October, 2009
Department of Pathology, Leiden University Medical Center, Leiden, The J Pathol. 2009 Sep;219(1):69-76.
DOI Direct Link
Maturation pathways of dendritic cells determine TAP1 and TAP2 levels and cross-presenting function.
Ability to cross-present exogenous antigens in the human leukocyte antigen...
9th October, 2009
Department of Otolaryngology, University of Pittsburgh Cancer Institute, J Immunother. 2009 Jun;32(5):465-73.
DOI Direct Link

View more research publications.

BioNews Results for TAP2

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BioPortfolio Logo
Association of HLA class I antigen abnormalities with disease progression and early recurrence in prostate cancer
MDLinx:  Oct 21 2009 11:07AM Matching: tap2

Patents:

Patents logo
US Patent No.Title
7208274 Rapid analysis of variations in a genome
7368527 HADDE71 polypeptides
7368531 Human secreted proteins
7378087 Method of enhancing an immune response
7390619 Optimization of immunomodulatory properties of genetic vaccines

View more patents.

TAP2 results (if any) from reagent suppliers

Google CSE Logo
TAP2 (G-20) Antibody sc-11473
TAP2 shRNA (h) Lentiviral Particles, sc-42983-V, 200 µl ... Western blot analysis of TAP2 expression in CTLL-2 whole cell lysate. Download ...
http://www.scbt.com/datasheet-11473-tap2-g-20-antibody.html...

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TAP2 antibodies: Signal Transduction > Protein Trafficking ...
TAP2 antibodies. ... Image Abreview Publication. ab60113 · TAP2 antibody. IHC-P, ELISA. Images. Rabbit polyclonal. Reacts with: ...
http://www.abcam.com/index.html?t=241229&pt=1&c=2377&ei=&mu=...

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TAP2 (H-210) Antibody sc-25612
rabbit polyclonal IgG, 200 µg/ml; epitope corresponding to amino acids 21-230 of TAP2 of human origin; recommended for detection of TAP2 of m, ...
http://www.scbt.com/datasheet-25612-tap2-h-210-antibody.html...

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Cell Surface Molecules / GPCRs
ATP-binding cassette sub-family B (MDR/TAP) transporter 2 (TAP2) polyclonal antibody, PAB-11139, $175.00. ATPase alpha polypeptide Cu++ transporting (ATP7A)
...
http://www.orbigen.com/dictionary/cat1089.htm...

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TAP2 siRNA (h) sc-42983
Click here for details. suitable control antibody: TAP2 (G-20): sc-11473; sqRT- PCR Primer also available: TAP2 (h)-PR: sc-42983-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-42983-tap2-sirna-h.html...

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IHC verified Antibodies - Orbigen Inc. - Orbigen Inc.
PAB-11139, ATP-binding cassette sub-family B (MDR/TAP) transporter 2 (TAP2) polyclonal antibody · NM_000544, 100 µg, $210.00 ...
http://www.orbigen.com/commerce/catalog/spcategory.jsp?categ...

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TAP2 (G-20) Antibody sc-11473
TAP2 (G-20) Anticorpo sc-11473 TAP2 (G-20) Antibody sc-11473.
http://www.scbt.com/it/datasheet-11473-tap2-g-20-antibody.ht...

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