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TAPBP


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Symbol:TAPBP
Name(s):TAP binding protein (tapasin)
Type:protein-coding
Organism:Homo sapiens
Synonyms:NGS17, TAPA, TPN, TPSN
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18248301 Observational study of gene-disease association. (HuGE Navigator)
18039656 A ternary complex between heavy chain, ERp57, and tapasin was observed and shown to be stabilized by a disulfide between both tapasinheavy chain and tapasin-ERp57.
11132161 Observational study of genotype prevalence. (HuGE Navigator)
15743475 Observational study of gene-disease association. (HuGE Navigator)
17389020 Observational study of gene-disease association. (HuGE Navigator)
11972874 tapasin is not required for calreticulin to bind to the alpha1 domain of MHC class I molecules
11970875 MHC class I molecules can optimize their peptide repertoire over time and that this process is dependent on tapasin.
11823531 recruits MHC class I molecules to TAP complex during antigen processing
17498802 Besides beta(2)m and tapasin, an extra unidentified component is also critical for the expression of certain human class I alleles.
14519625 Defects in tapasin and HLA class I antigen expression in primary maxillary sinus SCC lesions may play a role in the clinical course of the maxillary sinus cancer, because these defects were associated with poor prognosis.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDcalreticulin precursortapasin isoform 1 precursor--Pubmed
HPRDcoatomer protein complex, subunit betatapasin isoform 1 precursor--Pubmed
HPRDmajor histocompatibility complex, class I, A precursortapasin isoform 1 precursor--Pubmed
HPRDtransporter 1, ATP-binding cassette, sub-family Btapasin isoform 1 precursor--Pubmed
HPRDtransporter 2, ATP-binding cassette, sub-family B isoform 1tapasin isoform 1 precursor--Pubmed
HPRDtapasin isoform 1 precursorcoatomer protein complex, subunit gamma 1--Pubmed
HPRDtapasin isoform 1 precursorcoatomer protein complex, subunit gamma 1--Pubmed

Recent Publications on TAPBP:

Pubmed Logo
STAT1-dependent and STAT1-independent gene expression in murine immune cells following stimulation with interferon-alpha.
PURPOSE: The precise molecular targets of interferon-alpha (IFN-alpha)...
27th October, 2007
Integrated Biological Sciences Graduate Program, The Ohio State University Cancer Immunol Immunother. 2007 Nov;56(11):1845-52. Epub 2007 May 15.
DOI Direct Link
Genomic organization of duplicated major histocompatibility complex class I regions in Atlantic salmon (Salmo salar).
BACKGROUND: We have previously identified associations between major...
19th September, 2007
Department of Basic Science and Aquatic Medicine, Norwegian School of BMC Genomics. 2007 Jul 25;8:251.
DOI Direct Link
Transcriptome profiling of the small intestinal epithelium in germfree versus conventional piglets.
BACKGROUND: To gain insight into host-microbe interactions in a piglet...
19th September, 2007
Department of Animal Sciences, University of Illinois, Urbana, Illinois BMC Genomics. 2007 Jul 5;8:215.
DOI Direct Link
Cloning and expression analysis of an Atlantic salmon (Salmo salar L.) tapasin gene.
Loading of the major histocompatibility complex (MHC) class I molecule...
18th July, 2007
Department of Pharmaceutical Biosciences, School of Pharmacy, University Dev Comp Immunol. 2007;31(7):708-19. Epub 2006 Nov 20.
DOI Direct Link
Sequence variation within the major histocompatibility complex subregion centromeric of HLA class II in type 1 diabetes.
The extended major histocompatibility complex (xMHC) has been studied...
27th June, 2007
Department of Immunohaematology and Blood Transfusion, Leiden University Tissue Antigens. 2007 Apr;69(4):348-53.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
7598080 Diagnostic assay for source of inflammation
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7550300 Prediction of bare metal stent restenosis

View more patents.

TAPBP results (if any) from reagent suppliers

Google CSE Logo
TAPBP Antibody / TAPBP Antibodies
TAPBP Antibody / TAPBP Antibodies. ... TAPBP specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-tapbp.html...

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Baculo-EZ Expression Ready Clones
TAP binding protein (TAPBP), BVC-10062, $395.00. TNF-alpha, BVC-10264, $395.00. TNF-beta, BVC-10268, $395.00. TNF-beta, BVC-10309, $395.00 ...
http://www.orbigen.com/dictionary/cat1068.htm...

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TAPBP Antibody / TAPBP Antibodies
TAPBP Antibody / TAPBP Antibodies. ... TAPBP specific siRNA, sHRNA Plasmid과 shRNA Lentiviral Particles gene silencers 도 제공합니다. ...
http://www.scbt.com/ko/table-tapbp.html...

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TAPBPL (42-L) Antibody sc-100290
home » Lymphocyte Signaling » TAPBP Antibody / TAPBP Antibodies » TAPBPL (42-L): sc-100290 ... Additional TAPBP Antibodies . ...
http://www.scbt.com/datasheet-100290-tapbpl-42-l-antibody.ht...

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TAPBP Antibody / TAPBP Antibodies
TAPBP Antibody / TAPBP Antibodies. ... TAPBP 特异siRNA, shRNA 质粒和shRNA 慢病毒 颗粒基因沉默子均有产品提供。 产品包括: ...
http://www.scbt.com/zh/table-tapbp.html...

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TAPBPL siRNA (m) sc-154069
home » Lymphocyte Signaling » TAPBP Antibody / TAPBP Antibodies » TAPBPL siRNA ( m): sc-154069. TAPBPL siRNA, shRNA and Lentiviral Particle Gene Silencers ...
http://www.scbt.com/datasheet-154069-tapbpl-sirna-m.html...

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