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TEGT


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Symbol:TEGT
Name(s):testis enhanced gene transcript (BAX inhibitor 1)
Type:protein-coding
Organism:Homo sapiens
Synonyms:BI-1, TMBIM6
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17526500 BI-1 can inhibit the endoplasmic reticulum stress proteins as well as the accumulation of Rreactive oxygen species, thereby protecting the cells.
12875974 Results indicate that the human Bax inhibitor-1 gene may serve as a prostate cancer expression marker based on its overexpression in prostate carcinoma and prostate cancer cell lines.
16353209 BI-1 gene expression is conserved evolutionarily and may act as a key regulator of the apoptotic pathway in bronchiolalveolar carcinoma

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDBcl 2testis enhanced gene transcript--Pubmed
HPRDB-cell lymphoma protein 2 alpha isoformBax inhibitor 1--Pubmed
HPRDBCLXtestis enhanced gene transcript--Pubmed
HPRDBCL2-like 1 isoform 1Bax inhibitor 1--Pubmed

Recent Publications on TEGT:

Pubmed Logo
ERBB2 induces an antiapoptotic expression pattern of Bcl-2 family members in node-negative breast cancer.
PURPOSE: Members of the Bcl-2 family act as master regulators of...
14th January, 2010
Department of Obstetrics and Gynecology, University Medical Center of the Clin Cancer Res. 2010 Jan 15;16(2):451-60. Epub 2010 Jan 12.
DOI Direct Link
Characterization of BAX inhibitor-1 as a novel leukemia-associated antigen.
Using dendritic cells (DCs) electroporated with whole RNA isolated from...
6th November, 2009
Department of Hematology, Oncology, Rheumatology and Immunology, Leukemia. 2009 Oct;23(10):1818-24. Epub 2009 Jul 16.
DOI Direct Link
Turning off the unfolded protein response: an interplay between the apoptosis machinery and ER stress signaling.
Using dendritic cells (DCs) electroporated with whole RNA isolated from...
29th July, 2009
Cell Cycle. 2009 Jun 1;8(11):1643-4. Epub 2009 Jun 5.
Bax inhibitor 1 regulates ER-stress-induced ROS accumulation through the regulation of cytochrome P450 2E1.
This study investigated the molecular mechanism by which Bax inhibitor 1...
12th June, 2009
Department of Dental Pharmacology, School of Dentistry, Wonkwang J Cell Sci. 2009 Apr 15;122(Pt 8):1126-33.
DOI Direct Link
Refolding and reconstitution of human recombinant Bax inhibitor-1 into liposomes from inclusion bodies expressed in Escherichia coli.
In this study, we report the simultaneous refolding and reconstitution of...
3rd June, 2009
Department of Biochemistry, College of Veterinary Medicine, Chonnam Protein Expr Purif. 2009 Jul;66(1):35-8. Epub 2009 Jan 22.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
6545128 Anti-bax inhibitor protein antibodies
7034122 Antibodies to PRO1159 polypeptides
7034136 Nucleic acids encoding PRO1159 polypeptides
7037679 Nucleic acids encoding PRO1184 polypeptides
7039238 Data relationship model

View more patents.

TEGT results from Abnova

Google CSE Logo

Sponsored Results:

Abnova Logo
TEGT purified MaxPab mouse polyclonal antibody (B01P)
Mouse polyclonal antibody raised against a full-length human TEGT protein.
Symbol: TEGT  Alias: BI-1, TMBIM6
http://www.abnova.com/products/products_detail.asp?catalog_id=H00007009-B01P
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Abnova Logo
TEGT Recombinant Protein (P01)
TEGT( AAH00916.1, 1 a.a. - 237 a.a.) full-length recombinant protein with GST tag.
Symbol: TEGT  Alias: BI-1, TMBIM6
http://www.abnova.com/products/products_detail.asp?catalog_id=H00007009-P01
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Abnova Logo
TEGT monoclonal antibody, clone 20F248
Mouse monoclonal antibody raised against synthetic peptides of TEGT.
Symbol: TEGT  Alias: BI-1, TMBIM6
http://www.abnova.com/products/products_detail.asp?catalog_id=MAB0106
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Search for TEGT products at Abnova.

TEGT results (if any) from reagent suppliers

Google CSE Logo
BI-1 (FL-237) Antibody sc-28225
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, TEGT, 7009, 12q13.13, NM_003217 ...
http://www.scbt.com/el/datasheet-28225-bi-1-fl-237-antibody....

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Table of Contents
Bax inhibitor-1 originally called TEGT (testis enhanced gene transcript) inhibits the death inducing function of Bax. BI-1 is one of the few Bcl-2 family
...
http://www.invitrogen.com/etc/medialib/en/filelibrary/pdf.Pa...

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BI-1 siRNA (m) sc-37299
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Tegt, 110213, 15 F1, Q9D2C7 ...
http://www.scbt.com/datasheet-37299-bi-1-sirna-m.html...

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BI-1 (20F430) Antibody sc-73483
Humain, TEGT, 7009, 12q13.13, NM_003217 · P55061 · 600748. Souris, Tegt, 110213, 15 F1, Q9D2C7, Non disponible. Produits disponibles ...
http://www.scbt.com/fr/datasheet-73483-bi-1-20F430-antibody....

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Chromosome 15- Santa Cruz Biotechnology, Inc.
Tegt · 110213, 15 F1, Q9D2C7 · BI-1 · sc-37299 · NM_026669. C230021P08Rik, 380969, 15 F1, Q6GQX2, C230021P08Rik, sc-141881 · NM_001001884 ...
http://www.scbt.com/chromosome.php?number=15&page=17&species...

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Chromosome 12- Santa Cruz Biotechnology, Inc.
FMNL3 · sc-62329 · NM_198900, n/a. TEGT · 7009, 12q13.13, P55061 · BI-1 · sc- 37298 · NM_003217 · 600748 · KIAA1602 · 57701, 12q13.13, Q9HCH0 ...
http://www.scbt.com/chromosome.php?number=12&page=11&species...

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BI-1 Antibody / BI-1 Antibodies
製品名, カタログ番号, アイソタイプ, エピトープ, アプリケーション, 動物種. BI-1 ( G-19) 抗体, sc-12394, goat IgG, C-terminus (h), WB, IF, ELISA, m, r, h, pig ...
http://www.scbt.com/ja/table-bi-1.html...

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inhibitor 1 testis | bax inhibitor isoform | Bax expression in testes | bax inhibitor 1 antibodies | http://www.google.com/custom?q=Search tegt m | bax inhibitor | testis enhanced gene transcript | similar to testis enhanced gene transcript-like protein | Mol Cell. 2009 Mar 27 33 6 669-70. | .


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