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TIAM1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17702746 |
CD44 is an important regulator of HGF/c-Met-mediated in vitro and in vivo barrier enhancement, a process with essential involvement of Tiam1, Rac1, dynamin 2, and cortactin. |
| 18006851 |
16k PRL inhibits cell migration by blocking the Ras-Tiam1-Rac1-Pak1 signaling pathway in endothelial cells |
| 15295645 |
expression level of Tiam1 in two giant-cell lung carcinoma cell strains with high or low metastasis potential |
| 15899863 |
Tiam1 activates Rac and contributes to Rac signaling specificity through binding to IRSp53. |
| 15242348 |
Distinct phosphoinositides regulate different functions of Tiam1. |
| 15340013 |
Results suggest a role for Tiam1/Rac signaling in the control of cell-cell contacts through a novel ALCAM-mediated mechanism. |
| 17132223 |
Tiam1 plays a causal role in the metastasis of colorectal cancer |
| 17376711 |
Tiam1 transfection in colorectal cancer cells could upregulate the expression of Fascin-1, heat shock protein 27 (HSP27), high-mobility group box 1 (HMGB1), glutathione S-transferase omega 1 (GSTO1) and downregulate the expression of annexin IV. |
| 12446731 |
Tiam1 is c-Myc regulator, working in the nuclei to control c-Myc-related apoptosis |
| 12810717 |
Vav2 and Tiam1 may act as downstream effectors of Src, thereby regulating Rac1-dependent pathways that participate in Src-induced cell transformation | →View more information from publications. |
Recent Publications on TIAM1: |  |
Prognostic value of Tiam1 and Rac1 overexpression in nasopharyngeal carcinoma.
PURPOSE: This study is designed to investigate the roles of Tiam1 and Rac1... | 9th October, 2009
| Department of Otorhinolaryngology Head and Neck Surgery, XuanWu Hospital,
| ORL J Otorhinolaryngol Relat Spec. 2009;71(3):163-71. Epub 2009 Jun 9.
DOI Direct Link |
Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways.
Summary K-ras mutations are found in 40-50% of human colorectal adenomas... | 22nd September, 2009
| Department of Pathology, Addenbrooke's Hospital, University of Cambridge,
| Int J Exp Pathol. 2009 Oct;90(5):558-74.
DOI Direct Link |
A cell active chemical GEF inhibitor selectively targets the Trio/RhoG/Rac1 signaling pathway.
RhoGEFs (guanine nucleotide exchange factors of the Rho GTPase family) are... | 11th September, 2009
| Centre de Recherche de Biochimie Macromoleculaire, Universites Montpellier
| Chem Biol. 2009 Jun 26;16(6):657-66.
DOI Direct Link |
Expression of Tiam1 and VEGF-C correlates with lymphangiogenesis in human colorectal carcinoma.
OBJECTIVE: To investigate the relationship between Tiam1 and... | 6th August, 2009
| Department of Oncology, Southwest Hospital, Third Military Medical
| Cancer Biol Ther. 2009 Apr;8(8):689-95. Epub 2009 Apr 9.
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Distinct {beta}1 and {beta}3 integrin pathways converge to regulate cross-linked actin network (CLAN) formation in human trabecular meshwork (HTM) cells.
Purpose: Determine the beta1/beta3 integrin-mediated pathways that... | 1st August, 2009
| Ophthalmology & Visual Sciences, University of Wisconsin, Madison,
| Invest Ophthalmol Vis Sci. 2009 Jul 30.
DOI Direct Link |
→View more research publications. |
TIAM1 results (if any) from reagent suppliers | 
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TIAM1 antibody (ab54458) | Abcam
Rabbit polyclonal to TIAM1. TIAM1 modulates the activity of RHO like proteins and connects extracellular signals to cytoskeletal activities.
http://www.abcam.com/TIAM1-antibody-ab54458.html...
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Tiam1 (C-16) Antibody sc-872
See how others have used Tiam1 (C-16): sc-872 antibody and or Tiam1 (C-16) ... The Rac activator Tiam1 controls efficient T-cell trafficking and route of ...
http://www.scbt.com/datasheet-872-tiam1-c-16-antibody.html...
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Clone: 18F6 Isotype: IgG1 Kappa antibody reacts specifically with ...
Fleming, I.N., et al, (1999) Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation. J. Biol. Chem. ...
http://www.rockland-inc.com/objects/catalog/product/extras/2...
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Tiam1 (N-15) Antibody sc-871
See how others have used Tiam1 (N-15): sc-871 antibody and or Tiam1 (N-15) ... Guanine nucleotide exchange factor, Tiam1, directly binds to c-Myc and ...
http://www.scbt.com/datasheet-871-tiam1-n-15-antibody.html...
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10. Esufali,S. and Bapat,B. (2004) Cross-talk between Rac1
nucleotide exchange region of Tiam1. Nature 408, 682-688. 7. Eden,S., Rohatgi,R. , Podtelejnikov,A.V., Mann,M. and. Kirschner,M.W. (2002) Mechanism of ...
http://www.hypromatrix.com/Products/Primary_Antibody/Rac1.pd...
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Tiam1 siRNA (m) sc-36670
Click here for details. suitable control antibody: Tiam1 (C-16): sc-872; sqRT- PCR Primer also available: Tiam1 (m)-PR: sc-36670-PR, 20 µl ...
http://www.scbt.com/datasheet-36670-tiam1-sirna-m.html...
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2009 Addendum Non-priced.indd
TIAM1. Human/Mouse. Sheep IgG. AF5038. 100 µg. TOB1. Human. Goat IgG. AF5228. 100 µg. Uromodulin. Human. Sheep IgG. AF5144B ...
http://www.rndsystems.com/DAM_public/6139.pdf...
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