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TIMP1


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Symbol:TIMP1
Name(s):TIMP metallopeptidase inhibitor 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:CLGI, EPA, EPO, FLJ90373, HCI, TIMP
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17998244 TIMP-1 carries independent prognostic information when measured in blood, especially plasma.
18214300 Immunoassays showed significantly elevated content type 1 tissue inhibitor of metalloproteinases in tumors compared to adjacent histologically unchanged mucosa of patients with colorectal cancer.
12082592 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
12218659 Observational study of gene-disease association. (HuGE Navigator)
14605322 Observational study of gene-disease association. (HuGE Navigator)
15944607 Observational study of gene-disease association. (HuGE Navigator)
16061701 Observational study of gene-disease association. (HuGE Navigator)
16935611 Observational study of gene-disease association. (HuGE Navigator)
16940985 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16960901 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDmatrix metalloproteinase 1 preproproteintissue inhibitor of metalloproteinase 1 precursor--Pubmed
HPRDmatrix metalloproteinase 1 preproproteintissue inhibitor of metalloproteinase 1 precursor--Pubmed
HPRDmatrix metalloproteinase 3 preproproteintissue inhibitor of metalloproteinase 1 precursor--Pubmed
HPRDmatrix metalloproteinase 3 preproproteintissue inhibitor of metalloproteinase 1 precursor--Pubmed

Recent Publications on TIMP1:

Pubmed Logo
mRNA expression of matrix metalloproteinases (MMPs) 2 and 9 and tissue inhibitor of matrix metalloproteinases (TIMPs) 1 and 2 in childhood acute lymphoblastic leukemia: Potential role of TIMP1 as an adverse prognostic factor.
This study evaluates the mRNA expression profile of genes TIMP1, TIMP2,...
31st October, 2009
Department of Pediatrics, University of Sao Paulo, Ribeirao Preto, SP, Leuk Res. 2009 Oct 27.
DOI Direct Link
Age-associated changes in cardiac gene expression after preconditioning.
BACKGROUND: Cardiac protection afforded by ischemic preconditioning (IPC)...
28th October, 2009
Department of Anesthesiology, Stony Brook University School of Medicine, Anesthesiology. 2009 Nov;111(5):1052-64.
DOI Direct Link
Amphetamine and environmentally induced hyperthermia differentially alter the expression of genes regulating vascular tone and angiogenesis in the meninges and associated vasculature.
An amphetamine (AMPH) regimen that does not produce a prominent...
27th October, 2009
US Food and Drug Administration, National Center for Toxicological Synapse. 2009 Oct;63(10):881-94.
DOI Direct Link
Examining communication between ultraviolet (UV)-damaged cutaneous nerve cells and epidermal keratinocytes in vitro.
The exposure of the skin to Ultraviolet (UV) radiation is a stressful...
20th October, 2009
Arch Personal Care Products, L.P., 70 Tyler Place, South Plainfield, NJ Toxicol Ind Health. 2009 May-Jun;25(4-5):225-30.
DOI Direct Link
Novel strategy to identify genetic risk factors for COPD severity: a genetic isolate.
Studies using genetic isolates with limited genetic variation may be...
3rd October, 2009
University Medical Center Groningen, University of Groningen, Groningen, Eur Respir J. 2009 Sep 24.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Matrix Metalloproteinase-1/Tissue Inhibitor of Metalloproteinase-1 (MMP-1/TIMP-1) Ratio and Diabetic Foot Ulcers

Patents:

Patents logo
US Patent No.Title
7070976 Matrix metalloproteinase polypeptide
7273612 Soluble inhibitors of vascular endothelial growth factor and use thereof
7291461 Methods for identifying small molecules that modulate premature translation termination and nonsense mRNA decay
7332328 Microcolumn-platform based array for high-throughput analysis
7335357 Antagonists of neuropilin receptor function and use thereof

View more patents.

TIMP1 results (if any) from reagent suppliers

Google CSE Logo
The Abcam catalog
TIMP1 antibodies. ... TIMP1 antibody. Neut, WB, I-ELISA, sELISA. Rabbit polyclonal ... TIMP1 antibody - Carboxyterminal end. IP, WB, ELISA ...
http://www.abcam.com/index.html?t=1234&pt=1&c=344...

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Purified Anti-TIMP-1 Antibody - BioLegend
Purified Anti-TIMP-1 Antibody - TIMP-1 (Tissue inhibitor of metalloproteinase 1) is a glycoprotein that belongs to the protease inhibitor I35 (TIMP) family.
http://www.biolegend.com/purified-anti-timp-1-antibody-4466....

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TIMP1 antibody [102D1] (ab1827) | Abcam
Mouse monoclonal [102D1] to TIMP1. Tissue inhibitor of metalloproteinases 1 ( TIMP1) and Tissue inhibitor of metalloproteinases 2 (TIMP 2) have similar ...
http://www.abcam.com/TIMP1-antibody-102D1-ab1827.html...

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TIMP-1 (SPM355) Antibody sc-56489
Western blot analysis of TIMP-1 expression in non-transfected: sc-117752 (A) and human TIMP-1 transfected: sc-110547 (B) 293T whole cell lysates and ...
http://www.scbt.com/datasheet-56489-timp-1-spm355-antibody.h...

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Anti-TIMP1 Polyclonal Antibody
Polyclonal Antibody against TIMP1 for use in ELISA, Immunohistochemistry ( Paraffin), Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

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TIMP-1 (Yn5) Antibody sc-80365
TIMP-1 shRNA (h) Lentiviral Particles, sc-29505-V, 200 µl ... TIMP-1 (Yn5): sc- 80365. Western blot analysis of TIMP-1 expression in non-transfected: ...
http://www.scbt.com/datasheet-80365-timp-1-yn5-antibody.html...

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TIMP1 Antibody (N-term)
TIMP1 Antibody (N-term) Cell Function, TIMP1 Antibody (N-term) Cell Cycle Regulation.
http://www.abgent.com/products/catalog_no/AP6709a...

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