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TIMP3
| Symbol: | TIMP3 | | Name(s): | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | HSMRK222, K222, K222TA2, SFD | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18006877 |
Acrolein, a constituent of cigarette smoke and an endogenous mediator of oxidative stress, decreases Timp3 mRNA in mouse lung. |
| 11353449 |
Observational study of gene-disease association. (HuGE Navigator) |
| 14605322 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15223866 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15944607 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17033924 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17893005 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 17901377 |
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) |
| 17676308 |
TIMP3 is uniquely regulated by Oxidised, glycated LDL lipoproteins, which may contribute to microvascular abnormalities in diabetic retinopathy. |
| 17970209 |
Genetic changes in the timp-3 gene (TIMP-3) lead to a shift towards the myofibroblast phenotype in the fibroblast culture. | →View more information from publications. |
Recent Publications on TIMP3: |  |
Increased tumor necrosis factor alpha-converting enzyme activity induces insulin resistance and hepatosteatosis in mice.
Tumor necrosis factor alpha-converting enzyme (TACE, also known as ADAM17)... | 31st October, 2009
| Department of Internal Medicine, University of Rome Tor Vergata, Rome,
| Hepatology. 2009 Aug 25.
DOI Direct Link |
Multigene methylation analysis of conventional renal cell carcinoma.
Renal cell carcinoma (RCC) is the most common malignancy of the kidney.... | 29th October, 2009
| Department of Medical Genetics, Faculty of Medicine, Ege University,
| Urol Int. 2009;83(1):107-12. Epub 2009 Jul 27.
DOI Direct Link |
Spaceflight Modulates Expression of Extracellular Matrix, Adhesion and Profibrotic Molecules in Mouse Lung.
NASA has reported pulmonary abnormalities in astronauts on space missions,... | 24th October, 2009
| Loma Linda University.
| J Appl Physiol. 2009 Oct 22.
DOI Direct Link |
TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1.
OBJECTIVE: Atherosclerosis is accelerated in subjects with type 2 diabetes... | 24th October, 2009
| Department of Internal Medicine, University of Rome Tor Vergata, Rome,
| Diabetes. 2009 Oct;58(10):2396-401. Epub 2009 Jul 6.
DOI Direct Link |
Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia.
BACKGROUND: Translocations of the Mixed Lineage Leukemia (MLL) gene occur... | 20th October, 2009
| DSMZ-German Collection of Microorganisms and Cell Cultures, Braunschweig,
| Mol Cancer. 2009 Oct 16;8:86.
DOI Direct Link |
→View more research publications. |
TIMP3 results (if any) from reagent suppliers | 
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TIMP3 antibody (ab2169) | Abcam
Rabbit polyclonal to TIMP3. The tissue inhibitors of metalloproteinases (TIMPs) are naturally occurring proteins that specifically inhibit matrix ...
http://www.abcam.com/TIMP3-antibody-ab2169.html...
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TIMP-3 (MM0036-7D3) Antibody sc-101578
mouse monoclonal IgG1, 100 µg/ml; raised against recombinant TIMP-3 of human origin; recommended for detection of TIMP-3 of human origin by WB, ...
http://www.scbt.com/datasheet-101578-timp-3-mm0036-7d3-antib...
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The Abcam catalog
TIMP3 antibodies. ... TIMP3 antibody - Aminoterminal end. WB, ELISA. Rabbit polyclonal ... TIMP3 antibody - Loop 2. IHC-P, WB. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=8763&pt=1&c=344...
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TIMP Antibody / TIMP Antibodies
TIMP-3 (C-20) Antibody, sc-6836, goat IgG, C-terminus (h), WB, IP, IF, ELISA ... TIMP-3 (Z188) Antibody, sc-80367, mouse IgG1, FL (h), WB, IP, IF, IHC(P), ...
http://www.scbt.com/table-timp.html...
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OSM Induction of Chondrocyte MMP and TIMP-3 Gene Expression - R&D ...
Oncostatin M (OSM) induces human and bovine chondrocyte MMP-1, MMP-3 and MMP-13, and bovine chondrocyte TIMP-3 mRNA. This induction involves activation of ...
http://www.rndsystems.com/cb_detail_objectname_SU01_OSMInduc...
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Anti-Tissue Inhibitor of Metalloproteinase-4, Second Loop antibody ...
family members (TIMP-1, TIMP-2, and TIMP-3). This ... components (TIMP-3). The MMPs and TIMPs can be divided into two groups ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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TIMP-3 - R&D Systems
TIMP-3. TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. ...
http://www.rndsystems.com/molecule_detail.aspx?m=2179...
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