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TIMP4
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18301898 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18214300 |
Enzyme immunoassays showed the levels of type 4 tissue inhibitor of metalloproteinases were virtually the same in colorectal cancer and mucosa. |
| 16940965 |
Results indicate that MMP-26 and TIMP-4 may play an integral role during the conversion of high-grade prostatic intraepithelial neoplasia to invasive cancer and may also serve as markers for early prostate cancer diagnosis. |
| 12969699 |
Peaks during the early to mid-luteal phase. Seems to play role in hormonal regulation and endometrial tissue remodeling. |
| 15816637 |
TIMP-4 is expressed de novo in cervical cancer |
| 12374789 |
investigation of structural and functional differences between TIMP-4 and TIMP-2 by mutagenesis into C-terminal tails |
| 16809379 |
Maximal expression of TIMP-4 in the early and mid-secretory phase suggests its role during implantation and results show that TIMP-4 control the the relaese of MMP-26 in both stroma and uterine fluid. |
| 12475252 |
Progress curve analysis of MMP inhibition by TIMP-4 indicates that association rate constants and inhibition constants are similar to those for other TIMPs; TIMP-4 has a 5-fold lower binding affinity for proMMP-2 than does TIMP-2. |
| 15713681 |
TIMP-4 displayed negligible activity against TACE, N-TIMP-4 is a slow tight-binding inhibitor with low nanomolar binding affinity |
| 12466243 |
TIMP-4 is the major intraplatelet matrix metalloproteinase inhibitor and it is involved in regulation of platelet aggregation and recruitment. | →View more information from publications. |
Recent Publications on TIMP4: |  |
TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1.
OBJECTIVE: Atherosclerosis is accelerated in subjects with type 2 diabetes... | 24th October, 2009
| Department of Internal Medicine, University of Rome Tor Vergata, Rome,
| Diabetes. 2009 Oct;58(10):2396-401. Epub 2009 Jul 6.
DOI Direct Link |
Chondrogenic differentiation potential of osteoarthritic chondrocytes and their possible use in matrix-associated autologous chondrocyte transplantation.
ABSTRACT: INTRODUCTION: Autologous chondrocyte transplantation (ACT) is a... | 3rd September, 2009
| Tissue Engineering Laboratory and Berlin-Brandenburg Center for
| Arthritis Res Ther. 2009 Sep 2;11(5):R133.
DOI Direct Link |
Donor cell-type specific paracrine effects of cell transplantation for post-infarction heart failure.
Cell transplantation is an emerging therapy for treating post-infarction... | 3rd September, 2009
| Translational Cardiovascular Therapeutics, William Harvey Research
| J Mol Cell Cardiol. 2009 Aug;47(2):288-95. Epub 2009 May 23.
DOI Direct Link |
Promoter polymorphism (rs3755724, -55C/T) of tissue inhibitor of metalloproteinase 4 (TIMP4) as a risk factor for Kawasaki disease with coronary artery lesions in a Korean population.
Kawasaki disease (KD) is an acute febrile vasculitis that predominantly... | 2nd September, 2009
| Kohwang Medical Research Institute, School of Medicine, Kyung Hee
| Pediatr Cardiol. 2009 Apr;30(3):331-5. Epub 2008 Dec 2.
DOI Direct Link |
Activation of MMP8 and MMP13 by angiotensin II correlates to severe intra-plaque hemorrhages and collagen breakdown in atherosclerotic lesions with a vulnerable phenotype.
Angiotensin II (ATII)-mediated hypertension increases the risk for acute... | 6th August, 2009
| Department of Cardiology, Thoraxcenter, Erasmus University Medical Center,
| Atherosclerosis. 2009 May;204(1):26-33. Epub 2009 Jan 24.
DOI Direct Link |
→View more research publications. |
TIMP4 results (if any) from reagent suppliers | 
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TIMP4 antibody (ab2170) | Abcam
Rabbit polyclonal to TIMP4. The tissue inhibitors of metalloproteinases (TIMPs) are naturally occurring proteins that specifically inhibit matrix ...
http://www.abcam.com/TIMP4-antibody-ab2170.html...
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Anti-Tissue Inhibitor of Metalloproteinase-4, Second Loop antibody ...
inhibitor of metalloproteinase-4 gene (TIMP4) and localization of the TIMP4 and Timp4 genes to human chromosome 3p25 and mouse chrom- osome 6, respectively. ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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TIMP4 antibodies: Cardiovascular > Angiogenesis > Adhesion / ECM ...
TIMP4 antibodies. ... TIMP4 antibody - Carboxyterminal end. WB. Images. Rabbit polyclonal ... TIMP4 antibody - Loop 3. WB. Rabbit polyclonal. Reacts with: ...
http://www.abcam.com/index.html?t=8677&pt=1&c=344&ei=&mu=ra...
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TIMP-4 (C-16) Antibody sc-9375
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, TIMP4, 7079, 3p25.2, NM_003256 ...
http://www.scbt.com/ko/datasheet-9375-timp-4-c-16-antibody.h...
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TIMP4 proteins and peptides: Cancer > Invasion/microenvironment ...
TIMP4 proteins and peptides. ... TIMP4 peptide (Carboxyterminal end). WB, ELISA. ab41156 · TIMP4 peptide (Loop 1). WB, ELISA ...
http://www.abcam.com/index.html?t=8677&pt=2&c=4236&ei=&mu=ra...
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TIMP Antibody / TIMP Antibodies
製品名, カタログ番号, アイソタイプ, エピトープ, アプリケーション, 動物種. TIMP-1 (0.N.576) 抗体, sc-73172, mouse IgG1, FL (h), WB, h, r ...
http://www.scbt.com/ja/table-timp.html...
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All Metalloprotease inhibitors | Abcam
TIMP4 antibody. IP, WB, ELISA. Rabbit polyclonal ... TIMP4 antibody - Carboxyterminal end ... TIMP4 antibody - Loop 3. WB. Rabbit polyclonal ...
http://www.abcam.com/index.html?c=4363...
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