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TP53
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17975552 |
the potential use of R-Roscovitine as a bitargeted anticancer drug that functions by simultaneously causing p53 activation and NF-kappaB suppression. |
| 18025081 |
DEC1 is induced by the p53 family and DNA damage in a p53-dependent manner. p53 family proteins bind to, and activate, the promoter of the DEC1 gene. |
| 18238895 |
p53-mediated apoptosis occurs by a PIDD- and caspase 2-dependent mechanism, and p53's full transcriptional regulatory functions may be required only for events that are downstream of cytochrome c release |
| 18282133 |
the functions of p53 play substantial roles in many other pathologies as well as in the aging process [review] |
| 17683074 |
results suggest that gene-smoking and gene-gene interactions may impact the prevalence of p53 mutations in breast tumors |
| 17849423 |
p53 codon-249 mutations are associated with X-ray repair cross complementing protein 1 polymorphism Arg399Gln among the Guangxi population of China. |
| 17849424 |
p53 mutations at CpG dinucleotides provide further evidence for a molecular link between chronic inflammation and esophageal malignancy. |
| 17918207 |
among p53 Arg/Arg carriers, HPV infection, smoking, and drinking might further increase the risk of esophageal squamous cell carcinoma development |
| 17970695 |
These data suggest a more complex role for TRIM22 during T lymphocyte activation than merely as an antiproliferative factor. |
| 18038118 |
mutant p53 loses its ability to suppress DNMT1 expression, and thus enhances methylation levels of the p16 ( ink4A ) promoter and subsequently down-regulates p16(ink4A )protein. | →View more information from publications. |
Recent Publications on TP53: |  |
The emerging role of the distal Fallopian tube and p53 in pelvic serous carcinogenesis.
In their paper in this issue of the Journal, Xian et al have analysed in... | 3rd November, 2009
| Bute Medical School, University of St Andrews and Department of Pathology,
| J Pathol. 2009 Sep 25.
DOI Direct Link |
Detailed haplotype analysis at the TP53 locus in p.R337H mutation carriers in the population of Southern Brazil: evidence for a founder effect.
Due to patterns of migration, selection, and population expansion, founder... | 31st October, 2009
| International Agency for Research on Cancer (IARC), Lyon, Rhone, 69372,
| Hum Mutat. 2009 Oct 29.
DOI Direct Link |
Concurrent sequence variation of TP53 and TP73 genes in anaplastic astrocytoma.
Disruption or loss of tumor suppressor gene TP53 is implicated in the... | 31st October, 2009
| Departamento de Genetica, Laboratorio de Oncogenetica, Faculdade de
| Genet Mol Res. 2009 Oct 20;8(4):1257-63.
DOI Direct Link |
p53 expression by immunohistochemistry is an important determinant of survival in patients with chronic lymphocytic leukemia receiving frontline chemo-immunotherapy.
Although chromosome 17p abnormalities and TP53 mutations have been... | 30th October, 2009
| Department of Hematopathology.
| Leuk Lymphoma. 2009 Oct;50(10):1597-605.
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Benzene-induced mutational pattern in the tumour suppressor gene TP53 analysed by use of a functional assay, the functional analysis of separated alleles in yeast, in human lung cells.
Recent concern has centred on the effects of continuous exposure to low... | 29th October, 2009
| LCE EA2598, Toxicologie Industrielle et Environnementale, Universite du
| Arch Toxicol. 2009 Oct 28.
DOI Direct Link |
→View more research publications. |
TP53 results (if any) from reagent suppliers | 
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TP53 Antibody
Specific antibody for the gene product of TP53, the protein Tumor protein p53. Validated for specificity by gene-silencing with siRNA followed by Western ...
http://www.piercenet.com/products/Browse.cfm?fldID=1F59907A-...
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TP53 monoclonal antibody (M01)
TP53 (AAH03596, 94 a.a. ~ 202 a.a) partial recombinant protein with GST tag. ... Immunofluorescence of monoclonal antibody to TP53 (AT4310a) on A-431 cell . ...
http://www.abgent.com/products/catalog_no/AT4310a_TP53_monoc...
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Polyclonal Antibody to TIGAR (TP53-induced glycolysis and ...
Polyclonal Antibody to TIGAR (TP53-induced glycolysis and apoptosis regulator). Catalog No : IMG-5910A. Formulation : 100 ug in 200 ul PBS containing 0.2% ...
http://www.imgenex.com/tds/IMG-5910A.pdf...
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TP53 protein, p53 Human recombinant protein
Buy quality TP53 protein (e. coli), TP53, p53 Human recombinant protein, (n/an/a ). p53 Protein Human Recombinant; Tumor suppressor p53; Phosphoprotein p53; ...
http://www.genwaybio.com/product_info.php?products_id=45596...
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Antibodies to p53 and Related Proteins
rat ... Tp53(24842) human ... TP53(7157), rat, human, mouse, IHC (p), IP, WB, pricing ... human ... TP53(7157), human, ELISA (i), ICC, IHC, IP, WB, pricing
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http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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TP53 Q9NP68, p53 Mutant Form (361 - 377), Lys371 (Ac)
TP53 Q9NP68, p53 Mutant Form (361 - 377), Lys371 (Ac) Peptide.
http://www.abgent.com/products/catalog_no/SP2288b...
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TP53 Q9NP68, p53 Mutant Form (361-377), Lys371 (Ac)
Peptides , Cancer Research Peptides , TP53 Q9NP68, p53 Mutant Form (361-377), Lys371 (Ac); This peptide is derived from the tumor suppressor p53 mutant with
...
http://www.anaspec.com/products/product.asp?id=44027...
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