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TYMS


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Symbol:TYMS
Name(s):thymidylate synthetase
Type:protein-coding
Organism:Homo sapiens
Synonyms:HsT422, MGC88736, TMS, TS, TSase
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18322994 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18203297 Observational study of gene-disease association. (HuGE Navigator)
18221821 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18245544 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18267032 Observational study of gene-disease association. (HuGE Navigator)
18274813 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18285546 Observational study of gene-disease association. (HuGE Navigator)
18299612 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17716232 single nucleotide polymorphism of thymidylate synthase in colorectal cancer (Review)
14578129 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDE2F transcription factor 1Homo sapiens chromosome 18, reference assembly.E2F1 interacts with the TYMS chromatin.-Pubmed
BINDE2F transcription factor 4Homo sapiens chromosome 18, reference assembly.E2F4 interacts with the TYMS chromatin.-Pubmed

Recent Publications on TYMS:

Pubmed Logo
Association of Molecular Markers With Toxicity Outcomes in a Randomized Trial of Chemotherapy for Advanced Colorectal Cancer: The FOCUS Trial.
PURPOSE: Predicting efficacy and toxicity could potentially allow...
28th October, 2009
Oncology & Clinical Research and Pathology & Tumour Biology Sections, J Clin Oncol. 2009 Oct 26.
DOI Direct Link
The Role of Pemetrexed in Advanced Non Small-Cell Lung Cancer: Special Focus on Pharmacology and Mechanism of Action.
Pemetrexed is a newer antifolate drug that has been approved as first-line...
21st October, 2009
Department of Medical Oncology&Hematology, Cantonal Hospital, Curr Drug Targets. 2009 Sep 19.
Transcription factors LSF and E2Fs: tandem cyclists driving G0 to S?
Cell cycle progression in mammalian cells from G(1) into S phase requires...
21st October, 2009
Department of Biology and Program in Molecular Biology, Cell Biology and Cell Cycle. 2009 Jul 15;8(14):2146-51. Epub 2009 Jul 21.
Polymorphisms in one-carbon metabolism pathway genes and risk for bladder cancer in a Tunisian population.
Cigarette smoking is the most important risk factor for bladder cancer....
20th October, 2009
Laboratory of Genetics, Immunology and Human Pathology, Faculty of Cancer Genet Cytogenet. 2009 Nov;195(1):43-53.
DOI Direct Link
Pharmacogenetics in Oncology: A Promising Field.
Pharmacogenetics is a rapidly developing field, especially in oncology. In...
20th October, 2009
Department of Clinical Oncology, PO Box 9600, 2300 RC Leiden, Leiden Curr Pharm Des. 2009 Oct 15.

View more research publications.

BioNews Results for TYMS

: RSS Logo
BioPortfolio Logo
Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: The FOCUS Trial
MDLinx:  Oct 30 2009 9:27AM Matching: tyms

Clinical Trials:

Clinical Trials Logo
A Phase I Trial of ZD1694 (TOMUDEX), an Inhibitor of Thymidylate Synthase, in Pediatric Patients With Advanced Neoplastic Disease

Patents:

Patents logo
US Patent No.Title
5300659 Heptitols
5670144 Anti-herpes virus and cytomegalovirus polyester oligomers
5670489 Oligonucleotide analogues
5672625 Sulfonic stilbene derivatives in the treatment of viral diseases
5728731 Anti-herpes virus and cytomegalovirus polyamide oligomers

View more patents.

TYMS results (if any) from reagent suppliers

Google CSE Logo
Protein Modification - Methylation Antibody
AP6746bNEW, TRMT5 Antibody (C-term), WB, E, H. AT4425aNEW, TYMS monoclonal antibody (M01), ELISA,IF,IHC-P,S-ELISA,WB-Ce,WB-Re, H ...
http://www.abgent.com/products/category/protein_modification...

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TS (J-25) Antibody sc-134130
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, TYMS, 7298, 18p11.32, P04818 ...
http://www.scbt.com/datasheet-134130-ts-j-25-antibody.html...

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Thymidylate Synthase Antibody #3766
This process is catalyzed by thymidylate synthase (TS or TYMS), a homodimer composed of two 30 kDa subunits. TS is an intracellular enzyme that provides the
...
http://www.cellsignal.com/products/3766.html...

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TYSY Antibody (C-term)
Thymidylate synthase; TSase; TS; TYMS. Application Data: Calculated MW: 35716 Da . TYSY Antibody (C-term). Western blot analysis of TYSY antibody (C-term) ...
http://www.abgent.com/products/catalog_no/AP6682b_TYSY_Antib...

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Thymidylate Synthase Antibody
dylate synthase (TS or TYMS), a homodimer composed of two 30 kDa subunits. TS is an intracellular enzyme that provides the sole de novo source of ...
http://www.cellsignal.com/pdf/3766.pdf...

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Antibody Products - IgG Polyclonal Antibodies - GenWay
TYMS; TS - Rabbit anti Thymidylate Synthase; TSase; TS; EC 2.1.1.45; Thymidylate synthase, IgG Polyclonal ELISA, IHC, IP , WB, Source: Rabbit ...
https://www.genwaybio.com/all_polyclonal_antibodies.php?fl=R...

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TS Antibody / TS Antibodies
PRODUCT NAME, CATALOG #, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. TS (2D8.D11) Antibody, sc-66091, mouse IgG1, FL (h), WB, IF, IHC(P), human ...
http://www.scbt.com/table-ts.html...

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