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UBA7

Symbol:	UBA7
Name(s):	ubiquitin-like modifier activating enzyme 7
Type:	protein-coding
Organism:	Homo sapiens
Synonyms:	D8, MGC12713, UBA1B, UBE1L, UBE2
Links:	Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications
Publication Link	Summary of findings
14976209	RA treatment of APL and other RA-responsive leukemic cells induced expression of UBE1L and ISG15 as well as intracellular ISG15 conjugates. A physical association was found between UBE1L and ISG15 in vivo.
11891284	UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia

Recent Publications on UBA7:
Deficiency of a potential 3p21.3 tumor suppressor gene UBE1L (UBA7) does not accelerate lung cancer development in K-rasLA2 mice. Genetic lesions in chromosomal region 3p21.3 marks one of the earliest...	11th March, 2009	Department of Molecular and Experimental Medicine, Scripps Research	Lung Cancer. 2009 Feb;63(2):194-200. Epub 2008 Jun 24. DOI Direct Link
The level of hepatitis B virus replication is not affected by protein ISG15 modification but is reduced by inhibition of UBP43 (USP18) expression. Hepatitis B virus (HBV) causes both acute and chronic infection of the...	22nd January, 2009	Department of Molecular and Experimental Medicine, The Scripps Research	J Immunol. 2008 Nov 1;181(9):6467-72.

UBA7 results (if any) from reagent suppliers

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