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UBE2B


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Symbol:UBE2B
Name(s):ubiquitin-conjugating enzyme E2B (RAD6 homolog)
Type:protein-coding
Organism:Homo sapiens
Synonyms:E2-17kDa, HHR6B, HR6B, RAD6B, UBC2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
14981545 MCF10A cells stably transfected with antisense RAD6B display hypersensitivity to damage-inducing drugs.
17050667 These data reveal a potentially important role for transcriptionally active beta-catenin in the regulation of Rad6B gene expression, and link aberrant beta-catenin signaling with transcriptional deregulation of Rad6B and breast cancer development.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDUbiquitin conjugating enzyme E2Bubiquitin protein ligase E3 component n-recognin 2--Pubmed
HPRDubiquitin-conjugating enzyme E2BC6orf133 protein--Pubmed
HPRDubiquitin-conjugating enzyme E2Bpostreplication repair protein hRAD18p--Pubmed
HPRDubiquitin-conjugating enzyme E2Bpostreplication repair protein hRAD18p--Pubmed

Recent Publications on UBE2B:

Pubmed Logo
RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells.
H2B ubiquitylation has been implicated in active transcription but is not...
6th August, 2009
The Rockefeller University, New York, NY 10065, USA. Cell. 2009 May 1;137(3):459-71.
DOI Direct Link
Direct characterization of E2-dependent target specificity and processivity using an artificial p27-linker-E2 ubiquitination system.
Little attention has been paid to the specificity between E2 and the...
7th March, 2009
Korea Basic Science Institute, Korea. BMB Rep. 2008 Dec 31;41(12):852-7.
Expression of atrophy mRNA relates to tendon tear size in supraspinatus muscle.
Skeletal muscle atrophy and fatty infiltration develop after tendon...
12th February, 2009
Department of Orthopedics, University Hospital Balgrist, University of Clin Orthop Relat Res. 2009 Feb;467(2):457-64. Epub 2008 Oct 22.
DOI Direct Link
Novel variants in UBE2B gene and idiopathic male infertility.
The UBE2B gene encodes ubiquitin-conjugating enzyme, which is involved in...
10th October, 2008
Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad-500 007, J Androl. 2008 Sep-Oct;29(5):564-71. Epub 2008 May 22.
DOI Direct Link
Novel UBE2B-associated polymorphisms in an azoospermic/oligozoospermic population.
AIM: To assess whether abnormalities exist in the UBE2B gene in a...
19th August, 2008
Division of Reproductive Endocrinology, 30 North Medical Drive, University Asian J Androl. 2008 May;10(3):461-6.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7598080 Diagnostic assay for source of inflammation
6706867 DNA array sequence selection
6753314 Protein-protein complexes and methods of using same
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
6919184 Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents

View more patents.

UBE2B results (if any) from reagent suppliers

Google CSE Logo
UBE2B Antibody (N-term)
UBE2B Antibody (N-term). The anti-UBE2B Pab (Cat. #AP2115a) is used in Western blot to detect UBE2B in Jurkat cell lysate. ...
http://www.abgent.com/products/catalog_no/AP2115a_UBE2B_Anti...

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Ube2B proteins and peptides: Cell Biology > Proteolysis ...
Ube2B proteins and peptides. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab73536 · Ube2B protein (His tag). SDS-PAGE ...
http://www.abcam.com/index.html?t=14180&pt=2&c=1039&ei=&mu=r...

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Protein Modification - Ubiquitination Antibody
AP2115b, UBE2B Antibody (C-term), WB, IHC, E, H. AP2115a, UBE2B Antibody (N-term ) ... AT4428aNEW, UBE2B monoclonal antibody (M06), ELISA,WB-Re,WB-Tr, H ...
http://www.abgent.com/products/category/protein_modification...

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UBE Antibody / UBE Antibodies
UBE2B shRNA Plasmid (h): sc-106915-SH. UBE2B shRNA (h) Lentiviral Particles: sc- 106915-V. UBE2B ... UBE2B shRNA Plasmid (m): sc-154849-SH. UBE2B shRNA (m) ...
http://www.scbt.com/ja/table-ube.html...

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Ubiquitin (Ub) is a 76 amino acid highly conserved eukaryotic ...
UBE2B C-term Antibody. AP2128b. UCHL5 C-term Antibody. AP2147b. USP21 N-term Antibody ... UBE2B N-term Antibody. AP2128a. UCHL5 N-term Antibody. AP2148a ...
http://www.abgent.com/downloads/Ubiquitination.pdf...

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UBE2B siRNA (h) sc-106915
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: UBE2B ...
http://www.scbt.com/pt/datasheet-106915-ube2b-sirna-h.html...

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All Ubiquitin E2 Enzymes | Abcam
UBCH6/UBE2E1 protein (His tag). Conjugation, SDS-PAGE. ab81569 · UBCH6/UBE2E1 protein (His tag). Conjugation, SDS-PAGE. ab67118 · Ube2B antibody ...
http://www.abcam.com/index.html?c=1039...

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