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UBE2D2
| Symbol: | UBE2D2 | | Name(s): | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15001359 |
Data show that binding of the CNOT4 RING finger to the ubiquitin-conjugating enzyme (E2) UbcH5B is highly selective. |
| 15280377 |
UbcH5B/C are E2s for Mdm2, which contribute to the maintenance of low levels of p53 and Mdm2 in unstressed cells; inhibition of p53 ubiquitination and degradation by targeting UbcH5B/C is not sufficient to up-regulate p53 transcriptional activity. |
Recent Publications on UBE2D2: |  |
Origin and evolution of ubiquitin-conjugating enzymes from Guillardia theta nucleomorph to hominoid.
The origin of eukaryotic ubiquitin-conjugating enzymes (E2s) can be traced... | 9th October, 2009
| State Key Laboratory of Reproductive Biology, Institute of Zoology,
| Gene. 2009 Nov 15;447(2):72-85. Epub 2009 Aug 5.
DOI Direct Link |
A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.
Covalent attachment of ubiquitin to substrates is crucial to protein... | 20th August, 2009
| Division of Biomedical Genetics, Department of Physiological Chemistry,
| Mol Syst Biol. 2009;5:295. Epub 2009 Aug 18.
DOI Direct Link |
Direct characterization of E2-dependent target specificity and processivity using an artificial p27-linker-E2 ubiquitination system.
Little attention has been paid to the specificity between E2 and the... | 7th March, 2009
| Korea Basic Science Institute, Korea.
| BMB Rep. 2008 Dec 31;41(12):852-7.
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E2-c-Cbl recognition is necessary but not sufficient for ubiquitination activity.
The E2 ubiquitin-conjugating enzymes UbcH7 and UbcH5B both show specific... | 4th February, 2009
| Department of NMR Spectroscopy, Bijvoet Center for Biomolecular Research,
| J Mol Biol. 2009 Jan 16;385(2):507-19. Epub 2008 Nov 1.
DOI Direct Link |
Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation.
c-Cbl is the E3 ubiquitin ligase that ubiquitinates the epidermal growth... | 23rd December, 2008
| Department of Cellular Regulation, Research Institute for Microbial
| Mol Biol Cell. 2008 Aug;19(8):3454-62. Epub 2008 May 28.
DOI Direct Link |
→View more research publications. |
UBE2D2 results (if any) from reagent suppliers | 
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UBE2D2 antibody (ab58248) | Abcam
Mouse monoclonal to UBE2D2. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins ...
http://www.abcam.com/UBE2D2-antibody-ab58248.html...
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UBE2D2 siRNA (m) sc-154851
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: UBE2D2 ...
http://www.scbt.com/ja/datasheet-154851-ube2d2-sirna-m.html...
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All Ubiquitin E2 Enzymes | Abcam
UBE2D2 protein (Human). Conjugation, SDS-PAGE. ab81575 · UBE2D2 protein (Tagged) . Conjugation, SDS-PAGE. ab59313 · UBE2D2 protein (Tagged). SDS-PAGE ...
http://www.abcam.com/index.html?c=1039...
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UBE2D (C-15) Antibody sc-15000
Western blot analysis of UBE2D2 expression in non-transfected: sc-117752 (A) and mouse UBE2D2 transfected: sc-124411 (B) 293T whole cell lysates and rat ...
http://www.scbt.com/datasheet-15000-UBE2D-c-15-antibody.html...
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Protein Modification - Ubiquitination Antibody
AT4431aNEW, UBE2D1 monoclonal antibody (M01), ELISA,IHC-P,S-ELISA,WB-Re, H. AT4432aNEW, UBE2D2 monoclonal antibody (M02), ELISA,IHC-P,S-ELISA,WB-Ce,WB-Re, H
...
http://www.abgent.com/products/category/protein_modification...
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UBE2D2 (Y-20) Antibody sc-100617
UBE2D2 (Y-20) Anticorps sc-100617 UBE2D2 (Y-20) Antibody sc-100617.
http://www.scbt.com/fr/datasheet-100617-UBE2D2-y-20-antibody...
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FabGennix Inc. International >> Products
The Nedd3 interacts with several partners including SCNN1A, SCNNiB, UBE2D2 etc., via ww2 and ww3 domains. Nedd4 has at least 2 homologues, ...
http://www.fabgennix.com/prod_details.asp?myproduct=E3%20ubi...
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