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UBE2D3
| Symbol: | UBE2D3 | | Name(s): | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | E2(17)KB3, MGC43926, MGC5416, UBC4/5, UBCH5C | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17420285 |
Knocking down UBE2D3 by RNA interference leads to blockage oof retinoic acid induced chclin D1 degradation and cell cycle arrest. |
| 15280377 |
UbcH5B/C are E2s for Mdm2, which contribute to the maintenance of low levels of p53 and Mdm2 in unstressed cells; inhibition of p53 ubiquitination and degradation by targeting UbcH5B/C is not sufficient to up-regulate p53 transcriptional activity. |
| 12215439 |
Transducin beta-gamma is a substrate of UbcH5c (UBE2D3), UbcH7 (UBE2L3) and the ubiquitin-proteasome pathway only following the dissociation of transducin alpha from beta-gamma. Transducin beta-gamma is protected from ubiquitylation by phosducin. |
Recent Publications on UBE2D3: |  |
Origin and evolution of ubiquitin-conjugating enzymes from Guillardia theta nucleomorph to hominoid.
The origin of eukaryotic ubiquitin-conjugating enzymes (E2s) can be traced... | 9th October, 2009
| State Key Laboratory of Reproductive Biology, Institute of Zoology,
| Gene. 2009 Nov 15;447(2):72-85. Epub 2009 Aug 5.
DOI Direct Link |
Direct activation of protein kinases by unanchored polyubiquitin chains.
TRAF6 is a ubiquitin ligase that is essential for the activation of... | 2nd October, 2009
| Department of Molecular Biology, University of Texas, Southwestern Medical
| Nature. 2009 Sep 3;461(7260):114-9. Epub 2009 Aug 12.
DOI Direct Link |
PCNA is ubiquitinated by RNF8.
The ubiquitination of PCNA is an essential event in the operation of the... | 12th February, 2009
| Department of Biochemistry and Molecular Biology, New York Medical
| Cell Cycle. 2008 Nov 1;7(21):3399-404.
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A ubiquitin-conjugating enzyme, ube2d3.2, regulates xMLK2 and pronephros formation in Xenopus.
The Jun N-terminal kinase kinase kinase MLK2 is required for the formation... | 9th August, 2008
| Department of Medical Biology, Cancer Research Centre, Laval University,
| Differentiation. 2008 Apr;76(4):431-41. Epub 2007 Nov 15.
DOI Direct Link |
Physical and functional interactions between ZIP kinase and UbcH5.
Zipper-interacting protein kinase (ZIPK) is a widely expressed... | 25th July, 2008
| Department of Immunology, Graduate School of Pharmaceutical Sciences,
| Biochem Biophys Res Commun. 2008 Aug 8;372(4):708-12. Epub 2008 Jun 2.
DOI Direct Link |
→View more research publications. |
UBE2D3 results (if any) from reagent suppliers |
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UBE2D (C-15) Antibody sc-15000
Western blot analysis of UBE2D3 expression in non-transfected: sc-117752 (A) and mouse UBE2D3 transfected: sc-124412 (B) 293T whole cell lysates. Download ...
http://www.scbt.com/datasheet-15000-UBE2D-c-15-antibody.html...
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All Ubiquitin E2 Enzymes | Abcam
UBE2D3 protein (Human). Conjugation, SDS-PAGE. ab81571 · UBE2D3 protein (Tagged) . Conjugation, SDS-PAGE. ab59314 · UBE2D3 protein (Tagged). SDS-PAGE ...
http://www.abcam.com/index.html?c=1039...
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UBE Antibody / UBE Antibodies
UBE2D3 (Y-25) 抗体, sc-100618, mouse IgG1, FL (h), WB, IP, ELISA, human .... UBE2D3 shRNA Plasmid (h): sc-41681-SH. UBE2D3 shRNA (h) ...
http://www.scbt.com/ja/table-ube.html...
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Protein Modification - Ubiquitination Antibody
AT4432aNEW, UBE2D2 monoclonal antibody (M02), ELISA,IHC-P,S-ELISA,WB-Ce,WB-Re, H . AT4433aNEW, UBE2D3 monoclonal antibody (M01), ELISA,S-ELISA,WB-Ce,WB-Re, H ...
http://www.abgent.com/products/category/protein_modification...
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UBE2D3 siRNA (h) sc-41681
Click here for details. contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: UBE2D3 (h)-PR: sc-41681-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-41681-UBE2D3-sirna-h.html...
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Cell Biology: primary antibodies, proteins, peptides, kits | Abcam
... UBE2D1 proteins and peptides (5) · UBE2D2 antibodies (2) · UBE2D2 proteins and peptides (3) · UBE2D3 antibodies (2) · UBE2D3 proteins and peptides (3) ...
http://www.abcam.com/index.html?cl=246&pageconfig=productmap...
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UBE2D3 (m): 293T Lysate sc-124412
UBE2D3 (Y-25): sc-100618. Western blot analysis of UBE2D3 expression in non- transfected: sc-117752 (A) and mouse UBE2D3 transfected: sc-124412 (B) 293T ...
http://www.scbt.com/ko/datasheet-124412-ube2d3-m-293t-lysate...
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