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UBE2E2


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Symbol:UBE2E2
Name(s):ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLJ25157, UBCH8
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15545318 Ubiquitin charging can function as a nuclear import trigger, and identify a novel link between E2 regulation and karyopherin-mediated transport.
15485925 Ubc8 is a major ISG15-conjugating enzyme responsible for protein ISGylation upon interferon stimulation
11786535 Siah proteins function as E3 ubiquitin-protein ligases

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDubiquitin-conjugating enzyme E2E 2ring finger protein 8 isoform 1--Pubmed
HPRDubiquitin-conjugating enzyme E2E 2U-box domain containing 5 isoform a--Pubmed

Recent Publications on UBE2E2:

Pubmed Logo
Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes.
BACKGROUND: Ubiquitin (E3) ligases interact with specific ubiquitin...
21st June, 2008
Department of Molecular Cardiology, Lerner Research Institute, The BMC Struct Biol. 2008 May 16;8:26.
DOI Direct Link
E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.
An E3 ubiquitin ligase mediates the transfer of activated ubiquitin from...
29th January, 2008
Department of Biochemistry, University of Washington, Box 357350, Seattle, Nat Struct Mol Biol. 2007 Oct;14(10):941-8. Epub 2007 Sep 16.
DOI Direct Link
Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import.
Ubiquitin is a small polypeptide that is conjugated to proteins and...
20th January, 2005
Department of Cell Biology, University of Oklahoma Health Sciences Center, J Cell Biol. 2004 Nov 22;167(4):649-59. Epub 2004 Nov 15.
DOI Direct Link
The RING finger protein, RNF8, interacts with retinoid X receptor alpha and enhances its transcription-stimulating activity.
Retinoid X receptor alpha (RXR alpha) is a member of the steroid hormone...
21st June, 2004
Department of Molecular Pathobiochemistry, Gifu University School of J Biol Chem. 2004 Apr 30;279(18):18926-34. Epub 2004 Feb 23.
DOI Direct Link
cDNA cloning, characterization, and chromosome mapping of UBE2E3 (alias UbcH9), encoding an N-terminally extended human ubiquitin-conjugating enzyme.
A cDNA encoding a third member of human class III ubiquitin-conjugating...
16th August, 2000
Department of Molecular Pathobiochemistry, Gifu University School of Cytogenet Cell Genet. 1999;84(1-2):99-104.

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

UBE2E2 results (if any) from reagent suppliers

Google CSE Logo
UBE2E2 (S-20) Antibody sc-130052
UBE2E2 (S-20): sc-130052. Immuno-peroxidase staining of formalin fixed, ... Western blot analysis of UBE2E2 expression in Jurkat whole cell lysate. ...
http://www.scbt.com/datasheet-130052-UBE2E2-s-20-antibody.ht...

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UBE2E2 antibodies: Cell Biology > Proteolysis / Ubiquitin ...
UBE2E2 antibodies. ... UBE2E2 antibodies. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication. ab58254 · UBE2E2 antibody ...
http://www.abcam.com/index.html?t=232277&pt=1&c=1039&ei=&mu=...

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UBE2E2 siRNA (m) sc-154846
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: UBE2E2 ...
http://www.scbt.com/ja/datasheet-154846-UBE2E2-sirna-m.html...

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RNF8 antibody (ab15850) | Abcam
It has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ...
http://www.abcam.com/RNF8-antibody-ab15850.html...

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UBE2E2 (S-20) Antibody sc-130052
UBE2E2 (S-20) Anticorpo sc-130052 UBE2E2 (S-20) Antibody sc-130052.
http://www.scbt.com/it/datasheet-130052-UBE2E2-s-20-antibody...

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All Ubiquitin E2 Enzymes | Abcam
UBE2E2 antibody. WB. Images. Mouse monoclonal. Reacts with: Hu. ab66257 · UBE2E3 antibody. WB, ELISA. Images. Mouse polyclonal. Reacts with: Hu. Predicted: ...
http://www.abcam.com/index.html?c=1039...

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Cell Biology: primary antibodies, proteins, peptides, kits | Abcam
... UBE2D4 proteins and peptides (1) · UBE2E2 antibodies (1) · UBE2E3 antibodies (4) · UBE2E3 proteins and peptides (4) · UBE2I / UBC9 antibodies (4) ...
http://www.abcam.com/index.html?cl=246&pageconfig=productmap...

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