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UBE2G2


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Gene DB Home
Symbol:UBE2G2
Name(s):ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)
Type:protein-coding
Organism:Homo sapiens
Synonyms:UBC7
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16582478 Structural comparison of human UBE2G2 with yeast Ubc7 indicated that the overall structures are similar except for the long loop region and the C-terminal helix.
16407162 interrupting a specific E2-E3 interaction can selectively inhibit endoplasmic reticulum -associated degradation
12869571 Ubc7 mediates inositol 1,4,5-trisphosphate receptor ubiquitination and is a component of the endoplasmic reticulum-associated degradation pathway

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDautocrine motility factor receptorubiquitin-conjugating enzyme E2G 2 isoform 1--Pubmed
HPRDautocrine motility factor receptorubiquitin-conjugating enzyme E2G 2 isoform 1--Pubmed
HPRDCBLubiquitin-conjugating enzyme E2G 2 isoform 1--Pubmed
HPRDUbiquitin conjugating enzyme E2G2ubiquitin protein ligase E3A isoform 2--Pubmed
HPRDUbiquitin conjugating enzyme E2G2ubiquitin conjugating enzyme E2, J2 isoform 1--Pubmed
HPRDubiquitin-conjugating enzyme E2G 2 isoform 1Ubiquitin conjugating enzyme E2 J2--Pubmed
HPRDubiquitin-conjugating enzyme E2G 2 isoform 1UbcH7 associated protein 1--Pubmed
HPRDubiquitin-conjugating enzyme E2G 2 isoform 1Ubiquitin protein ligase E3A--Pubmed

Recent Publications on UBE2G2:

Pubmed Logo
The E3 Ubiquitin Ligases Hrd1 and gp78 Bind to and Promote Cholera Toxin Retro-translocation.
Monitoring Editor: Ramanujan S. Hegde To cause disease, cholera toxin (CT)...
30th October, 2009
Department of Cell and Developmental Biology, University of Michigan Mol Biol Cell. 2009 Oct 28.
DOI Direct Link
The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains.
Ubiquitination plays a major role in many aspects of hematopoiesis....
22nd September, 2009
Central Hematology Laboratory, Nijmegen Centre for Molecular Life Leukemia. 2009 Aug;23(8):1480-9. Epub 2009 Apr 2.
DOI Direct Link
Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78.
The activity of RING finger ubiquitin ligases (E3) is dependent on their...
25th July, 2009
Structural Biophysics Laboratory, Center for Cancer Research, National Mol Cell. 2009 Jun 26;34(6):674-85.
DOI Direct Link
Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2.
Lys-48-linked polyubiquitination regulates a variety of cellular processes...
27th March, 2009
Laboratory of Molecular Biology, National Institute of Diabetes and Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3722-7. Epub 2009 Feb 17.
DOI Direct Link
Thiopurine S-methyltransferase pharmacogenetics: autophagy as a mechanism for variant allozyme degradation.
OBJECTIVE: Thiopurine S-methyltransferase (TPMT)*3A is degraded much more...
7th March, 2009
Division of Clinical Pharmacology, Department of Molecular Pharmacology Pharmacogenet Genomics. 2008 Dec;18(12):1083-94.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7598031 Method for the detection of gene transcripts in blood and uses thereof
6919184 Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
6979551 Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
7132234 Methods and compositions for the identification of anti-poxvirus agents
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

View more patents.

UBE2G2 results (if any) from reagent suppliers

Google CSE Logo
UBE2G2 (2E6) Antibody sc-100613
UBE2G2 (2E6): sc-100613. Immunoperoxidase staining of formalin-fixed, paraffin- embedded human liver tissue showing cytoplasmic localization. ...
http://www.scbt.com/datasheet-100613-ube2g2-2e6-antibody.htm...

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UBE2G2 Antibody (N-term)
UBE2G2 Antibody (N-term). The anti-UBE2G2 Pab (Cat. #AP2123a) is used in Western blot to detect UBE2G2 in Jurkat cell lysate. ...
http://www.abgent.com/products/catalog_no/AP2123a_UBE2G2_Ant...

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UBE2G2 siRNA (h) sc-76788
Click here for details. suitable control antibody: UBE2G2 (2E6): sc-100613; sqRT -PCR Primer also available: UBE2G2 (h)-PR: sc-76788-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-76788-ube2g2-sirna-h.html...

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Protein Modification - Ubiquitination Antibody
AP2123b, UBE2G2 Antibody (C-term), WB, E, H ... AT4436aNEW, UBE2G2 monoclonal antibody (M01), ELISA,IHC-P,S-ELISA,WB-Ce,WB-Re, H ...
http://www.abgent.com/products/category/protein_modification...

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UBE2G2 (2E6) Antibody sc-100613
UBE2G2 (2E6) Antikörper sc-100613 UBE2G2 (2E6) Antibody sc-100613.
http://www.scbt.com/de/datasheet-100613-ube2g2-2e6-antibody....

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Ubiquitin (Ub) is a 76 amino acid highly conserved eukaryotic ...
UBE2G2 C-term Antibody. AP2131a. USP2 N-term Antibody. AP2153a. USP29 N-term Antibody ... UBE2G2 N-term Antibody. AP2132b. USP3 C-term Antibody. AP2167b ...
http://www.abgent.com/downloads/Ubiquitination.pdf...

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UBE2G2 (m): 293T Lysate sc-124414
100 µg protein in 200 µl SDS-PAGE buffer; suitable as Western Blotting control for UBE2G2 antibodies; mouse UBE2G2 transfected 293T lysate; suitable control
...
http://www.scbt.com/ko/datasheet-124414-ube2g2-m-293t-lysate...

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