Wednesday November 25 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

UBE2V1


Suggest Content
Advertise Here
Gene DB Home
Symbol:UBE2V1
Name(s):ubiquitin-conjugating enzyme E2 variant 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:CIR1, CROC-1, CROC1, UBE2V, UEV-1, UEV1, UEV1A
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17709375 modification of proteins with Lys(63)-linked ubiquitin chains occurs through a UEV1A-independent substrate modification and UEV1A-dependent Lys(63)-linked ubiquitin chain synthesis mechanism
16129784 Data demonstrate that divergent activities of Ubc13 rely on its pairing with either of two Uevs, Uev1A or Mms2.
16893187 A structural model for the Ub-hUev1a-hUbc13-Ub tetramer was developed to gain chemical insight into the synthesis of Lys(63)-linked Ubiquitin chains.
17041755 These data provide evidence that Uev1A is a critical regulatory component in the NF-kappaB signaling pathway in response to environmental stresses and identify UEV1A as a potential proto-oncogene.

Recent Publications on UBE2V1:

Pubmed Logo
Origin and evolution of ubiquitin-conjugating enzymes from Guillardia theta nucleomorph to hominoid.
The origin of eukaryotic ubiquitin-conjugating enzymes (E2s) can be traced...
9th October, 2009
State Key Laboratory of Reproductive Biology, Institute of Zoology, Gene. 2009 Nov 15;447(2):72-85. Epub 2009 Aug 5.
DOI Direct Link
Direct activation of protein kinases by unanchored polyubiquitin chains.
TRAF6 is a ubiquitin ligase that is essential for the activation of...
2nd October, 2009
Department of Molecular Biology, University of Texas, Southwestern Medical Nature. 2009 Sep 3;461(7260):114-9. Epub 2009 Aug 12.
DOI Direct Link
Toll-like receptors-related genes in kidney transplant patients with chronic allograft nephropathy and acute rejection.
INTRODUCTION: Toll-like receptors (TLR) comprehend an emerging family of...
18th August, 2009
Laboratory of Clinical and Experimental Immunology - Nephrology Division, Int Immunopharmacol. 2009 Jun;9(6):673-6. Epub 2008 Dec 25.
DOI Direct Link
Leucettamol A: a new inhibitor of Ubc13-Uev1A interaction isolated from a marine sponge, Leucetta aff. microrhaphis.
A compound that inhibits the formation of a complex composed of the...
30th April, 2009
Graduate School of Science, Chiba University, 1-33 Yayoi-cho, Inage-ku, Bioorg Med Chem Lett. 2008 Dec 15;18(24):6319-20. Epub 2008 Oct 31.
DOI Direct Link
Biological significance of structural differences between two highly conserved Ubc variants.
Ubiquitin conjugating enzyme variants (Uev) Uev1 and Mms2 share >90%...
23rd January, 2009
Department of Microbiology and Immunology, University of Saskatchewan, 107 Biochem Biophys Res Commun. 2009 Jan 16;378(3):563-8. Epub 2008 Dec 3.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7598031 Method for the detection of gene transcripts in blood and uses thereof
6919184 Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
6979551 Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
7122345 Nucleic acid encoding a NOVX13 polypeptide

View more patents.

UBE2V1 results (if any) from reagent suppliers

Google CSE Logo
UBE2V1 (CROC1A) Antibody (C-term)
UBE2V1 (CROC1A) Antibody (C-term). Western blot analysis of anti-CROC1A Pab (Cat . #AP2164b) in CEM cell line lysate (35ug/lane). CROC1A(arrow) was detected ...
http://www.abgent.com/products/catalog_no/AP2164b_UBE2V1_CRO...

Thumbshot
UBE2V1 antibodies: Chromatin and Nuclear Signaling > Transcription ...
UBE2V1 antibodies. ... UBE2V1 antibody - Aminoterminal end. WB, ELISA. Images. Rabbit polyclonal. Reacts with: Hu. Terms and conditions · Legal ...
http://www.abcam.com/index.html?t=268981&pt=1&c=3423&ei=&mu=...

Thumbshot
Protein Modification - Ubiquitination Antibody
AP2164b, UBE2V1 (CROC1A) Antibody (C-term), WB, E, H. AP2164a, UBE2V1 (CROC1A) Antibody (N-term), WB, IHC, E, H. AP2157b, UBE2V1 Antibody (C-term), WB, E, H
...
http://www.abgent.com/products/category/protein_modification...

Thumbshot
UBE2V1 protein (His tag) (ab81565) | Abcam
UBE2V1 protein (His tag). Ubiquitin-conjugating E2 enzyme (UBE2V1) is located in the nucleus and can cause transcriptional activation of the human FOS ...
http://www.abcam.com/Ube2V1-protein-His-tag-ab81565.html...

Thumbshot
Ubiquitin (Ub) is a 76 amino acid highly conserved eukaryotic ...
UBE2V1 C-term Antibody. AP2137b. USP8 C-term Antibody. AP2175b. Dsk2 C-term Antibody ... UBE2V1 N-term Antibody. AP2137a. USP8 N-term Antibody. AP2175a ...
http://www.abgent.com/downloads/Ubiquitination.pdf...

Thumbshot
UBE2V2 +UBE2V1 proteins and peptides: Cell Biology > Cell Cycle ...
UBE2V2 +UBE2V1 proteins and peptides. ... Image Abreview Publication. ab81567 · UBE2V2 +UBE2V1 protein (His tag). Conjugation, SDS-PAGE ...
http://www.abcam.com/index.html?t=281110&pt=2&c=3284&ei=&mu=...

Thumbshot
Abgent - Chromatin and Regulation Antibodies - Chromatin_regulation
AM1261a, UBC9 Antibody, WB, E, H, M. AP2164b, UBE2V1 (CROC1A) Antibody (C-term), WB, E, H. AP2164a, UBE2V1 (CROC1A) Antibody (N-term), WB, IHC, E, H ...
http://www.abgent.com/products/category/nuclear_signaling/ch...

Thumbshot

Search Bioportfolio and other Life Science Sites for UBE2V1, or search for UBE2V1 on BioPortfolio's antibody search engine.
This page has been viewed 98 times
Recent Search Terms used to find this page:
uev1a IHC | Ube2v1 | Ube2v1 | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.